Protein Alignment fa2h and SCS7

DIOPT Version :9

• Sequence 1: NP_610279.3
• Gene: fa2h / 35670
• FlyBaseID: FBgn0050502
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_013999.1
• Gene: SCS7 / 855315
• SGDID: S000004885
• Length: 384
• Species: Saccharomyces cerevisiae
• Alignment Length: 388
• Identity: 122/388 - (31%)
• Similarity: 190/388 - (48%)
• Gaps: 75/388 - (19%)

  Fly    13 SNDKFIVKYRQQYYDLSRFMHKHPGGINTLKGLNSGDMTARFLK---APPHSDAAMYLMR-EYKI 73
            :||.::....::.||::||:.:||||..::......|:| ..:|   ...|||:|..::. ||.|
Yeast    23 ANDCWVTYQNRKIYDVTRFLSEHPGGDESILDYAGKDIT-EIMKDSDVHEHSDSAYEILEDEYLI 86

  Fly    74 -----DPEDSR-KPKSSQRETLHHDEDGT-------LRQRPRETE-----DKNNNQVDDSMEH-L 119
                 |.|.:| ....:.:..:....|||       :::.|.|.:     |.:|    |..:| .
Yeast    87 GYLATDEEAARLLTNKNHKVEVQLSADGTEFDSTTFVKELPAEEKLSIATDYSN----DYKKHKF 147

  Fly   120 VDWSKAMLPQIANI---TDCYDEWVHKP-----VDRPLRLFDPWYLEMCTKTPWWLVPLFWIPVI 176
            :|.::.:|.||...   .|.|.:.:|:|     ...|  ||.. :||..|||.||:||:.|:||:
Yeast   148 LDLNRPLLMQILRSDFKKDFYVDQIHRPRHYGKGSAP--LFGN-FLEPLTKTAWWVVPVAWLPVV 209

  Fly   177 VKCAVEEFTTAWQDSNQL-AVFSGYFLFGVLLWSFLEYTLHRWVFHVKLSNKSGSWL------CT 234
                |.....|.::.||| |.|  .|..||.:|:.:||.|||::||.      ..||      ..
Yeast   210 ----VYHMGVALKNMNQLFACF--LFCVGVFVWTLIEYGLHRFLFHF------DDWLPESNIAFA 262

  Fly   235 FHFMIHGLHHKVPFDPMRLVFPPLPGAVLAAVIY------TPLSFVLSHPRVILSGALAGYLCYD 293
            .||::||.||.:|.|..|||.||....:|.|..|      .||.:..:.    .:|.|.||:|||
Yeast   263 THFLLHGCHHYLPMDKYRLVMPPTLFVILCAPFYKLVFALLPLYWAYAG----FAGGLFGYVCYD 323

  Fly   294 MMHYYLHYGNPSLWAFVH-MKRYHHHHHFSHQTLGYGISSPLWDVVFKTRI----HLRKLRYQ 351
            ..|::||:.  .|..|:. :|:||..||:.:..||:|::|..||.||.|.:    .|.|::|:
Yeast   324 ECHFFLHHS--KLPPFMRKLKKYHLEHHYKNYQLGFGVTSWFWDEVFGTYLGPDAPLSKMKYE 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fa2h	NP_610279.3	Cyt-b5	6..73	CDD:278597	19/63 (30%)
		FA_hydroxylase	117..341	CDD:294712	87/246 (35%)
SCS7	NP_013999.1	CYB5	31..224	CDD:227599	57/204 (28%)
		FA_hydroxylase	149..380	CDD:412761	88/251 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344070
Domainoid	1	1.000	105	1.000	Domainoid score	I1472
eggNOG	1	0.900	-	-		E1_COG3000
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56284
Inparanoid	1	1.050	154	1.000	Inparanoid score	I1097
Isobase	1	0.950	-	0	Normalized mean entropy	S2267
OMA	1	1.010	-	-		QHG55743
OrthoFinder	1	1.000	-	-		FOG0004076
OrthoInspector	1	1.000	-	-		oto99931
orthoMCL	1	0.900	-	-		OOG6_103477
Panther	1	1.100	-	-	LDO	PTHR12863
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R279
SonicParanoid	1	1.000	-	-		X2828
TreeFam	1	0.960	-	-
	16	15.740