DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fa2h and FAH1

DIOPT Version :9

Sequence 1:	NP_610279.3	Gene:	fa2h / 35670	FlyBaseID:	FBgn0050502	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_181023.1	Gene:	FAH1 / 818042	AraportID:	AT2G34770	Length:	237	Species:	Arabidopsis thaliana

Alignment Length:	232	Identity:	90/232 - (38%)
Similarity:	129/232 - (55%)	Gaps:	23/232 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 VDWSKAMLPQIANITDCYDEWVHKPV---DRPLRLFDPWYLEMCTKTPWWLVPLFWIPVIVKCAV 181
            ||..|.::.|:.::.:.|:||||:|:   :.| |.|...:.|..|.|.||.||:.|:||:|.|..
plant     8 VDLKKPLVFQVGHLGEDYEEWVHQPIATKEGP-RFFQSDFWEFLTLTVWWAVPVIWLPVVVWCIS 71

  Fly   182 EEFTTAWQDSNQLAVFSGYFLFGVLLWSFLEYTLHRWVFHVKLSNKSGSWLCTFHFMIHGLHHKV 246
            ...:...    .|.......:.|:.:|:|.||.|||:|||:|..:   .|..|.|::|||.|||.
plant    72 RSVSMGC----SLPEIVPIVVMGIFIWTFFEYVLHRFVFHIKTKS---YWGNTAHYLIHGCHHKH 129

  Fly   247 PFDPMRLVFPPLPGAVL-------AAVIYTPLSFVLSHPRVILSGALAGYLCYDMMHYYLHYGNP 304
            |.|.:||||||...|:|       |..|.||     |....:..|.:.||:.||:.|||||:..|
plant   130 PMDHLRLVFPPTATAILCFPFWNIAKAISTP-----STAPALFGGGMLGYVMYDVTHYYLHHAQP 189

  Fly   305 SLWAFVHMKRYHHHHHFSHQTLGYGISSPLWDVVFKT 341
            :.....::|:||.:|||..|..|:||:|.|||:||.|
plant   190 TRPVTKNLKKYHLNHHFRIQDKGFGITSSLWDIVFGT 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fa2h	NP_610279.3	Cyt-b5	6..73	CDD:278597
fa2h	NP_610279.3	FA_hydroxylase	117..341	CDD:294712	89/230 (39%)
FAH1	NP_181023.1	PLN02434	1..237	CDD:178053	90/232 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	143	1.000	Domainoid score	I1503
eggNOG	1	0.900	-	-		E1_COG3000
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56284
Inparanoid	1	1.050	180	1.000	Inparanoid score	I1461
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1049908at2759
OrthoFinder	1	1.000	-	-		FOG0004076
OrthoInspector	1	1.000	-	-		otm3094
orthoMCL	1	0.900	-	-		OOG6_103477
Panther	1	1.100	-	-	LDO	PTHR12863
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2828
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.830