DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fa2h and Cyb5b

DIOPT Version :9

Sequence 1:	NP_610279.3	Gene:	fa2h / 35670	FlyBaseID:	FBgn0050502	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_079834.2	Gene:	Cyb5b / 66427	MGIID:	1913677	Length:	146	Species:	Mus musculus

Alignment Length:	189	Identity:	35/189 - (18%)
Similarity:	60/189 - (31%)	Gaps:	75/189 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DIPKEAESNDKFIVKYRQQYYDLSRFMHKHPGGINTLKGLNSGDMTARFLKAPPHSDAAMYLMRE 70
            ::.|...:.:.::| ...:.||::||:.:||||...|......|.|..| :...||..|..::::
Mouse    27 EVAKRNSAEETWMV-IHGRVYDITRFLSEHPGGEEVLLEQAGADATESF-EDVGHSPDAREMLKQ 89

  Fly    71 Y---KIDPEDSRKPKSSQRETLHHDEDGTLRQRPRETEDKNNNQVDDSMEHLVDWSKAMLPQIAN 132
            |   .:.|.| .|||...::                 ..|||:
Mouse    90 YYIGDVHPSD-LKPKGDDKD-----------------PSKNNS---------------------- 114

  Fly   133 ITDCYDEWVHKPVDRPLRLFDPWYLEMCTKTPWWLVPLFWIPVIVKCAVEEFTTAWQDS 191
               |...|.                       :|.||:.. .:::......|   |.||
Mouse   115 ---CQSSWA-----------------------YWFVPIVG-AILIGFLYRHF---WADS 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fa2h	NP_610279.3	Cyt-b5	6..73	CDD:278597	18/69 (26%)
fa2h	NP_610279.3	FA_hydroxylase	117..341	CDD:294712	9/75 (12%)
Cyb5b	NP_079834.2	Cyt-b5	22..95	CDD:278597	18/69 (26%)
Cyb5b	NP_079834.2	MIP	<119..139	CDD:294134	4/43 (9%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R279
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030