DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11125 and Enkd1

DIOPT Version :9

Sequence 1:	NP_001260771.1	Gene:	CG11125 / 35669	FlyBaseID:	FBgn0033174	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_001099650.1	Gene:	Enkd1 / 291975	RGDID:	1307357	Length:	346	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	90/393 - (22%)
Similarity:	146/393 - (37%)	Gaps:	114/393 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 KLAAKEPTRPKWMPP-LRRSSSVMGDSKAEKPAAKGKTIKQNSLQNGRSTSRSQHQLAVAVPAEG 108
            :::...|..|...|. .||.:|..|       ..:|..:|.:.|.:||....|        |..|
  Rat     7 RISGPIPPDPTLCPDYYRRPASAQG-------RLEGNALKLDLLTSGRDLDSS--------PPRG 56

  Fly   109 ERFDGLEERNPILYDPSENLESENLQEPSSDTDIDRCQSCGTNRSSTSIAIQTEDITDELYLTNA 173
            .|.                       .|.:...::|.|     |....:.:|...|:    |.:.
  Rat    57 PRI-----------------------RPGAREILERGQ-----RGVGDVLLQLGGIS----LGSG 89

  Fly   174 LKKCNFDARSILEESGAKYGENYKPMQYENEEDLEQL---PLSARSNSSK----QSRFNMSEMEA 231
            :.....|.:...:|:..:..|..:..| :.|...||.   ||.|...|.|    :||......|.
  Rat    90 VSPKRKDPKDHEKENLRRIKEIQRRFQ-DQERSREQAQPKPLKALWRSPKYDSVESRVKARMKEL 153

  Fly   232 MPMTEAEPANYGASDDEAPLSARSRF--------TTASNVTTISSKSK----------------R 272
            .|.:..|||.:        |.|.||.        .::..:|...||:|                :
  Rat   154 GPASVTEPAQF--------LRAHSRCGPGLPPSRASSPQLTLPGSKAKGPGLGVDFISHNARAAK 210

  Fly   273 REHKLGSRDEVRLPRYLEKQK-------------------------REKAVAKQLAESLDPDCPR 312
            |..:..||....|.:.||:|:                         |::|.|::.::. ||..|.
  Rat   211 RAPRRHSRSLQVLAQVLEQQRQAQEHYNATQKGHVPHYLLERRDLWRKEAEARKRSQP-DPSMPP 274

  Fly   313 GHVLLSDQDRLTHLTNAKKRYEQLVNELNHMPMTAQTLRVRNRKAEIDKELTTVEEDIRIYSKAK 377
            ||.|:.:..||..|.|..:...:|:.||..:|..|.:||.:..:||:|::|..:||.|:|:|:.|
  Rat   275 GHTLMPENQRLETLNNLLQSQSKLLRELVLLPAGADSLRAQGYRAELDRKLVQIEEAIKIFSRPK 339

  Fly   378 VFV 380
            |||
  Rat   340 VFV 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11125	NP_001260771.1	Enkurin	284..375	CDD:290575	32/115 (28%)
Enkd1	NP_001099650.1	Enkurin	243..337	CDD:290575	28/94 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353815
Domainoid	1	1.000	60	1.000	Domainoid score	I10333
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1383928at2759
OrthoFinder	1	1.000	-	-		FOG0009640
OrthoInspector	1	1.000	-	-		oto97654
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR21490
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	9.000