Protein Alignment kappaB-Ras and Rasd2

DIOPT Version :10

• Sequence 1: NP_610278.1
• Gene: kappaB-Ras / 35667
• FlyBaseID: FBgn0040513
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_083458.1
• Gene: Rasd2 / 75141
• MGIID: 1922391
• Length: 266
• Species: Mus musculus
• Alignment Length: 207
• Identity: 51/207 - (24%)
• Similarity: 85/207 - (41%)
• Gaps: 50/207 - (24%)

  Fly     2 LNAKIGKVGKVLVCGMKGVGKTALIEQLVYGHVNPETELHPTIEDIY--VASVDTGRGGARETLR 64
            ||.......:::|.|...|||::::.:.:.|..  |.:..|||||.:  |.::.    |....|.
Mouse    12 LNVPAKNSYRMVVLGASRVGKSSIVSRFLNGRF--EDQYTPTIEDFHRKVYNIH----GDMYQLD 70

  Fly    65 IYDTAGLQGEQQQLPRHYLQFP----------DAFVLVYDPMDPRSLD-------MLADIKADIE 112
            |.||:|         .|  .||          |.|:||:......|.|       .:.::|:.::
Mouse    71 ILDTSG---------NH--PFPAMRRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVKSCLK 124

  Fly   113 -KHKEKKEIPVVVLANVR-----ARAAPNPVEKVMDRANIWCQRERIKHYTVNAMERPSLYEPFT 171
             |.||..|:|:|:..|..     .|..|     .|:...:....|...::.|:|.:..::.|.|.
Mouse   125 NKTKEAAELPMVICGNKNDHSELCRQVP-----AMEAELLVSGDENCAYFEVSAKKNTNVNEMFY 184

  Fly   172 TL--CARL-HPM 180
            .|  .|:| |.|
Mouse   185 VLFSMAKLPHEM 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaB-Ras	NP_610278.1	Ras_like_GTPase	13..174	CDD:206648	45/187 (24%)
Rasd2	NP_083458.1	Rhes_like	20..266	CDD:133343	49/199 (25%)
		Effector region	48..56		5/7 (71%)
		Interaction with GNB1, GNB2 and GNB3. /evidence=ECO:0000250	189..235		4/8 (50%)