DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kappaB-Ras and Rala

DIOPT Version :9

Sequence 1:	NP_001137613.1	Gene:	kappaB-Ras / 35667	FlyBaseID:	FBgn0040513	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_525063.1	Gene:	Rala / 31332	FlyBaseID:	FBgn0015286	Length:	201	Species:	Drosophila melanogaster

Alignment Length:	176	Identity:	43/176 - (24%)
Similarity:	77/176 - (43%)	Gaps:	9/176 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KVLVCGMKGVGKTALIEQLVYGHVNPETELHPTIEDIYVASVDTGRGGARETLRIYDTAGLQGEQ 75
            ||::.|..||||:||..|.:|.....:.|  ||..|.|...|..  .|....:.|.|||| |.:.
  Fly    13 KVIMVGSGGVGKSALTLQFMYDEFVEDYE--PTKADSYRKKVVL--DGEEVQIDILDTAG-QEDY 72

  Fly    76 QQLPRHYLQFPDAFVLVYDPMDPRSLDMLADIKADIEKHKEKKEIPVVVLANVRARAAPNPVEKV 140
            ..:..:|.:..:.|:.|:...|..|.....:.:..|.:.|..:.||.:::.|   :...|...||
  Fly    73 AAIRDNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDESIPFLLVGN---KCDLNDKRKV 134

  Fly   141 -MDRANIWCQRERIKHYTVNAMERPSLYEPFTTLCARLHPMQTKST 185
             :....:..|:..:.:...:|..|.::.:.|..|...:...:|:.:
  Fly   135 PLSECQLRAQQWAVPYVETSAKTRENVDKVFFDLMREIRSRKTEDS 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaB-Ras	NP_001137613.1	Ras	11..173	CDD:278499	41/162 (25%)
kappaB-Ras	NP_001137613.1	Ras_like_GTPase	13..174	CDD:206648	39/161 (24%)
Rala	NP_525063.1	RalA_RalB	12..174	CDD:206710	42/168 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453045
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840