DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sPLA2 and Pla2g3

DIOPT Version :9

Sequence 1:	NP_001014501.1	Gene:	sPLA2 / 35665	FlyBaseID:	FBgn0033170	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_766379.2	Gene:	Pla2g3 / 237625	MGIID:	2444945	Length:	504	Species:	Mus musculus

Alignment Length:	138	Identity:	40/138 - (28%)
Similarity:	58/138 - (42%)	Gaps:	16/138 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EDEDIYNQALPPVPH----TGITVPGTKWCGPGNTAANFEDLGRERETDKCCRAHDHCDEIIESH 86
            |...|.....|...|    .|.|:|||.|||.||:|.|..:||.....|.|||.||.|.:.|...
Mouse   126 EKRAIEQSGAPDREHRRRRRGWTIPGTLWCGVGNSAENASELGVFHGPDLCCREHDQCPQTISPL 190

  Fly    87 GALHGLPTNTDWFPILKCTCEQQFINCLQAVNSITAKTLGRIYYG----------SRSRCFANGH 141
            ...:|: .|..:..|..|.|:.:|..||::.....:..:|..::.          .:..|.| .:
Mouse   191 QYNYGI-RNFRFHTISHCDCDARFQQCLRSQGDSISDIMGVAFFNVLEIPCFVLKEQEACVA-WN 253

  Fly   142 PTTGCKQY 149
            ...||:.|
Mouse   254 WWGGCRAY 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sPLA2	NP_001014501.1	PLA2_bee_venom_like	43..139	CDD:153093	31/105 (30%)
Pla2g3	NP_766379.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	115..143		4/16 (25%)
		Phospholipase A2-like. /evidence=ECO:0000250\|UniProtKB:Q9NZ20	146..287		36/118 (31%)
		PLA2_bee_venom_like	147..243	CDD:153093	30/96 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	285..350
		PLA2_group_III_like	295..422	CDD:153094
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835949
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8069
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.850