Protein Alignment so and SIX4

DIOPT Version :9

• Sequence 1: NP_476733.1
• Gene: so / 35662
• FlyBaseID: FBgn0003460
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_059116.3
• Gene: SIX4 / 51804
• HGNCID: 10890
• Length: 781
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 170/422 - (40%)
• Similarity: 211/422 - (50%)
• Gaps: 117/422 - (27%)

  Fly    30 SPTGLSGSVALHNNNNNNSSTSNNNNSTLDIMAHNGGGAGGGLH--------------LNSSSNG 80
            ||||...|.|.....|...|.|....:..::    .|||..||.              ..:::..
Human     5 SPTGQIASAADIKQENGMESASEGQEAHREV----AGGAAVGLSPPAPAPFPLEPGDAATAAARV 65

  Fly    81 GGGGGVVSGGGSG-------------GRENLPS-------FGFTQEQVACVCEVLQQAGNIERLG 125
            .|..|.|:...:|             ||.:..:       ..|:.:.||||||.|||.||::||.
Human    66 SGEEGAVAAAAAGAAADQVQLHSELLGRHHHAAAAAAQTPLAFSPDHVACVCEALQQGGNLDRLA 130

  Fly   126 RFLWSLPQCDKLQLNESVLKAKAVVAFHRGQYKELYRLLEHHHFSAQNHAKLQALWLKAHYVEAE 190
            ||||||||.|.|:.|||:|||:|:||||:|.|.|||.:||.|.|.:.||..||.||.||.|.|||
Human   131 RFLWSLPQSDLLRGNESLLKARALVAFHQGIYPELYSILESHSFESANHPLLQQLWYKARYTEAE 195

  Fly   191 KLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRSVLRDWYSHNPYPSPREKRDLAEAT 255
            :.||||||||.|||:||||||||||||||||.||||||||:.|::.|..|.||||.|||.||:.|
Human   196 RARGRPLGAVDKYRLRRKFPLPRTIWDGEETVYCFKEKSRNALKELYKQNRYPSPAEKRHLAKIT 260

  Fly   256 GLTTTQVSNWFKNRRQRDR------AAEHKDGS------TDKQH-------LDSSSD-------- 293
            ||:.|||||||||||||||      :....||:      :.|.|       |.||||
Human   261 GLSLTQVSNWFKNRRQRDRNPSETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLS 325

  Fly   294 SEME----------------------GSMLPSQSAQHQQQQQQQQHSPGNSSGNN---------- 326
            |.||                      ||::|:.:            ||...:||:
Human   326 SHMEPVYMQQIGNAKISLSSSGVLLNGSLVPAST------------SPVFLNGNSFIQGPSGVIL 378

  Fly   327 NGLHQQQLQHVAAEQGLQHHPHQPHPASNIAN 358
            |||:....|.||.        :.|..:|||.:
Human   379 NGLNVGNTQAVAL--------NPPKMSSNIVS 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
so	NP_476733.1	SIX1_SD	103..212	CDD:293483	72/108 (67%)
		homeodomain	223..274	CDD:238039	36/50 (72%)
SIX4	NP_059116.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55		14/53 (26%)
		SIX1_SD	108..217	CDD:293483	72/108 (67%)
		homeodomain	228..282	CDD:238039	38/53 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..321		19/50 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0775
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810