Protein Alignment so and Six2

DIOPT Version :10

• Sequence 1: NP_476733.1
• Gene: so / 35662
• FlyBaseID: FBgn0003460
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_038968544.1
• Gene: Six2 / 366542
• RGDID: 1310792
• Length: 298
• Species: Rattus norvegicus
• Alignment Length: 324
• Identity: 185/324 - (57%)
• Similarity: 220/324 - (67%)
• Gaps: 40/324 - (12%)

  Fly    98 LPSFGFTQEQVACVCEVLQQAGNIERLGRFLWSLPQCDKLQLNESVLKAKAVVAFHRGQYKELYR 162
            ||:|||||||||||||||||.||||||||||||||.|:.|..||||||||||||||||.::|||:
  Rat     4 LPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYK 68

  Fly   163 LLEHHHFSAQNHAKLQALWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKE 227
            :||.|.||..||||||.|||||||:||||||||||||||||||||||||||:|||||||||||||
  Rat    69 ILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKE 133

  Fly   228 KSRSVLRDWYSHNPYPSPREKRDLAEATGLTTTQVSNWFKNRRQRDRAAEHKDG-STDKQHLDSS 291
            |||||||:||:|||||||||||:|||||||||||||||||||||||||||.|:. ..:.::.:||
  Rat   134 KSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERYEENSENSNSS 198

  Fly   292 SDSEMEGSMLPSQSAQHQQQQQQQQHSPGNSSGNNNGLHQQQLQHVAAEQGLQHHPHQP------ 350
            |.:.:..|:  :.|.:......:.:.:|..:.           .|.::...|...|..|
  Rat   199 SHNPLASSL--NGSGKSVLGSSEDEKTPSGTP-----------DHSSSSPALLLSPPPPPGLPSL 250

  Fly   351 HPASNIANVAATKSSGGGGGGGVSAAAAAQMQMPPLTAAVAYSHLHSVMGAM--PMTA-MYDMG 411
            |...:....:|......||||.           .||      .|.||:..::  ||:| :.|:|
  Rat   251 HSLGHPPGPSAVPVPVPGGGGA-----------DPL------QHHHSLQDSILNPMSANLVDLG 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
so	NP_476733.1	SIX1_SD	103..212	CDD:465293	91/108 (84%)
		homeodomain	223..274	CDD:238039	47/50 (94%)
Six2	XP_038968544.1	SIX1_SD	9..118	CDD:465293	91/108 (84%)
		homeodomain	129..180	CDD:238039	47/50 (94%)