Protein Alignment so and Six5

DIOPT Version :9

• Sequence 1: NP_476733.1
• Gene: so / 35662
• FlyBaseID: FBgn0003460
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_035513.1
• Gene: Six5 / 20475
• MGIID: 106220
• Length: 719
• Species: Mus musculus
• Alignment Length: 419
• Identity: 159/419 - (37%)
• Similarity: 201/419 - (47%)
• Gaps: 86/419 - (20%)

  Fly    57 TLDIMAHNGGGAGGGLHLNSSSNGGGGGGVVSGGGSGGRENL----PSFGFTQEQVACVCEVLQQ 117
            ||.........||.|     .:......|..||.|| .||.:    ....|:.||||||||.|.|
Mouse    35 TLQAAEGEAAAAGAG-----DAAAAADSGSPSGPGS-PRETVTEVPTGLRFSPEQVACVCEALLQ 93

  Fly   118 AGNIERLGRFLWSLPQCDKLQLNESVLKAKAVVAFHRGQYKELYRLLEHHHFSAQNHAKLQALWL 182
            ||:..||.|||.:||..::|:.::.||:|:|:|||.||:|.|||:|||...|.|.:||.||.|:|
Mouse    94 AGHAGRLSRFLGALPPAERLRGSDPVLRARALVAFQRGEYAELYQLLESRPFPAAHHAFLQDLYL 158

  Fly   183 KAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRSVLRDWYSHNPYPSPRE 247
            :|.|.|||:.|||.||||.|||:|:|||||:||||||||.|||||:||:.|:..|..|.||:|.|
Mouse   159 RARYHEAERARGRALGAVDKYRLRKKFPLPKTIWDGEETVYCFKERSRAALKACYRGNRYPTPDE 223

  Fly   248 KRDLAEATGLTTTQVSNWFKNRRQRDRAA--------EHKDGSTDKQHLDSSSDSEME---GSM- 300
            ||.||..|||:.|||||||||||||||..        ...||:...:...|.|..::|   .||
Mouse   224 KRRLATLTGLSLTQVSNWFKNRRQRDRTGTGGGAPCKSESDGNPTTEDESSRSPEDLERGVASMA 288

  Fly   301 --LPSQSAQHQQQQQQQQHSPGNSS------------------------------GNNNGL---- 329
              .|:||:............|.:||                              |.|:.|
Mouse   289 AEAPAQSSIFLAGATSPATCPASSSILVNGSFLAASSPPAVLLNGSPVIINSLALGENSSLGPLL 353

  Fly   330 --------HQQQLQHVA-AEQGLQHHPHQPHPASNIANVAATKSSGGGGGGGVSAAAAAQMQMP- 384
                    .|..||.|: |:..|...|.......:.|...|.::.|..|..|.....|....:|
Mouse   354 LTGGSAPQPQPSLQGVSEAKNSLVLDPQTGEVRLDEAQSEAPETKGVHGTTGEEIPGALPQVVPG 418

  Fly   385 -------PLTAAVAYSHLHSVMGAMPMTA 406
                   |||.           ||:|..|
Mouse   419 PPPASTFPLTP-----------GAVPAVA 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
so	NP_476733.1	SIX1_SD	103..212	CDD:293483	64/108 (59%)
		homeodomain	223..274	CDD:238039	34/50 (68%)
Six5	NP_035513.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..73		12/43 (28%)
		SIX1_SD	79..188	CDD:293483	64/108 (59%)
		homeodomain	199..250	CDD:238039	34/50 (68%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	241..287		15/45 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0775
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810