Protein Alignment so and Six4

DIOPT Version :10

• Sequence 1: NP_476733.1
• Gene: so / 35662
• FlyBaseID: FBgn0003460
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_061513992.1
• Gene: Six4 / 1270857
• VectorBaseID: AGAMI1_001860
• Length: 425
• Species: Anopheles gambiae
• Alignment Length: 338
• Identity: 151/338 - (44%)
• Similarity: 195/338 - (57%)
• Gaps: 52/338 - (15%)

  Fly    33 GLSGSVALHN---NNNNNSSTSNNNNSTLDIMAH-----NGGGAGGGLHLNSSSNGGG------- 82
            |..||..|.|   ||.|.|||.::||:..:::|:     ||..:.|.|....::|...
Mosquito   106 GSPGSGVLVNGSSNNTNGSSTGSSNNNGGNLLANNSVVPNGLPSCGALPRTDNNNSSYLQSLQPP 170

  Fly    83 ------GGGVVSGGGSGGRENLP--------SFGFTQEQVACVCEVLQQAGNIERLGRFLWSLPQ 133
                  .....|||...|..|.|        .|.|:.||:.|:||.|||.|::|:|..|||||..
Mosquito   171 PPHPQLPASAASGGHPLGSSNGPIGPDLERKCFSFSPEQIQCMCEALQQEGDLEKLATFLWSLSP 235

  Fly   134 CDKLQLNESVLKAKAVVAFHRGQYKELYRLLEHHHFSAQNHAKLQALWLKAHYVEAEKLRGRPLG 198
            .|.:..|||:|:|:|:||:|||.|.|||.:||.|.||.:.||.|||||.||||.||||:||||||
Mosquito   236 SDLISGNESLLRARALVAYHRGLYHELYAVLESHFFSPKYHADLQALWFKAHYREAEKVRGRPLG 300

  Fly   199 AVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRSVLRDWYSHNPYPSPREKRDLAEATGLTTTQVS 263
            ||.|||:|:|:|||:||||||||.||||||||:.|:|.|:.|.||:|.||:.||:.||||.||||
Mosquito   301 AVDKYRLRKKYPLPKTIWDGEETVYCFKEKSRNALKDCYTRNRYPTPDEKKTLAKKTGLTLTQVS 365

  Fly   264 NWFKNRRQRDRAAEHKDGSTDKQHLDSSSDSEMEGSMLP----SQSAQHQQQQQQQQHSPGNSSG 324
            |||||||||||..:             ||..::..|:||    .....:|:......:.|.
Mosquito   366 NWFKNRRQRDRTPQ-------------SSRPDLMMSVLPVTPDQMDGSYQRLFNVANYGPA---- 413

  Fly   325 NNNGLHQQQLQHV 337
              :|.|...:..|
Mosquito   414 --HGYHANDMYAV 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
so	NP_476733.1	SIX1_SD	103..212	CDD:465293	67/108 (62%)
		homeodomain	223..274	CDD:238039	36/50 (72%)
Six4	XP_061513992.1	None