DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment so and six6

DIOPT Version :9

Sequence 1:NP_476733.1 Gene:so / 35662 FlyBaseID:FBgn0003460 Length:416 Species:Drosophila melanogaster
Sequence 2:NP_001093696.1 Gene:six6 / 100101705 XenbaseID:XB-GENE-483146 Length:244 Species:Xenopus tropicalis


Alignment Length:276 Identity:136/276 - (49%)
Similarity:181/276 - (65%) Gaps:56/276 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    98 LPSFGFTQEQVACVCEVLQQAGNIERLGRFLWSLP----QCDKLQLNESVLKAKAVVAFHRGQYK 158
            ||...|:.:|||.|||.|:::|:||||||||||||    .|:.|..|||||:|:|:||||.|.::
 Frog     4 LPILNFSPQQVAGVCETLEESGDIERLGRFLWSLPVAPAACEALNKNESVLRARAIVAFHTGNFR 68

  Fly   159 ELYRLLEHHHFSAQNHAKLQALWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSY 223
            |||.:||:|.|:..::.|||||||:|||.|||||||||||.|.|||||:||||||||||||:.::
 Frog    69 ELYHILENHKFTKDSYTKLQALWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTH 133

  Fly   224 CFKEKSRSVLRDWYSHNPYPSPREKRDLAEATGLTTTQVSNWFKNRRQRDRAAEHKDGSTDKQHL 288
            ||||::|.:||:||..:|||:|.:||:||:|||||.|||.|||||||||||||            
 Frog   134 CFKERTRHLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAA------------ 186

  Fly   289 DSSSDSEMEGSMLPSQSAQHQQQQQQQQHSPGNSSGNNNGLHQQQLQHVAAEQGLQHHPHQP--- 350
                            :|:::.|||......|:|.|.:             |:|      :|   
 Frog   187 ----------------AAKNRLQQQVLSQGTGHSLGPD-------------ERG------EPLGS 216

  Fly   351 --HPASNIANVAATKS 364
              .||:::::.|||.:
 Frog   217 ASSPAASLSSKAATSA 232

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
soNP_476733.1 SIX1_SD 103..212 CDD:293483 72/112 (64%)
homeodomain 223..274 CDD:238039 34/50 (68%)
six6NP_001093696.1 SIX1_SD 9..122 CDD:318970 72/112 (64%)
homeodomain 130..178 CDD:238039 28/47 (60%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X333
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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