Protein Alignment ced-9 and Buffy

DIOPT Version :9

• Sequence 1: NP_499284.1
• Gene: ced-9 / 3565776
• WormBaseID: WBGene00000423
• Length: 280
• Species: Caenorhabditis elegans
• Sequence 2: NP_523702.1
• Gene: Buffy / 36251
• FlyBaseID: FBgn0040491
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 307
• Identity: 58/307 - (18%)
• Similarity: 110/307 - (35%)
• Gaps: 85/307 - (27%)

 Worm    20 MATGEMKEFLGIKGTEPTDFGI---NSDAQDLPSPSRQASTRRMS-IGESIDGKIN---DWEEPR 77
            |||.:.:..|..:......|..   ::...::....::.:.||:| :.:::..|::   .|:..:
  Fly    19 MATTQSERLLQAQNRRKFSFPATLHSASLLEVGGGPKETTRRRLSNVSDAVTRKLSYTIGWKAAQ 83

 Worm    78 LDIEGFVVD-------YFTHRIRQNGM-----------EWFGAPGLPCGVQPEHEMMRVMGTIFE 124
            :..:..:..       |...|:|::|:           ...|:..:.. |:.....::|:|...|
  Fly    84 IPAQDIISQGRCLCGHYIKRRLRRSGLFNKKLGLQRIRSILGSTSMGI-VRDVFPAVQVLGDELE 147

 Worm   125 KKHAENFETFCEQLLAVPRISFSLYQDVVRTV-----GNAQTDQCPMSYGRLIGLISFGGFVAAK 184
            :.|              |||    |..|.|.:     |...|   |.:...|:|.:       .:
  Fly   148 RMH--------------PRI----YNGVARQICRNPGGEFHT---PDAVSLLLGAV-------GR 184

 Worm   185 MMESVELQ-GQVRNLFVYTSLFIKTRIRNNWKEHNRSWDDFMTLGKQMKEDYERAEAEKVGRRKQ 248
            .:..||:. .:|.:||..........:|....|:         |.|.|:...|..|.|.|....:
  Fly   185 ELFRVEITWSKVISLFAIAGGLSVDCVRQGHPEY---------LPKLMESVSEVIEDELVPWINE 240

 Worm   249 NRRWSMIGAGV------------TAGAIGIV-GVVVCG---RMMFSL 279
            |..||.|...|            |...||:| |:::..   |.:|:|
  Fly   241 NGGWSGINTHVLPTTNSLNPLEWTTLVIGVVFGLILVFMILRFIFNL 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ced-9	NP_499284.1	Bcl-2_like	86..227	CDD:132900	28/164 (17%)
Buffy	NP_523702.1	Bcl-2_like	99..250	CDD:132900	39/188 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4728
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6964
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760