Protein Alignment Dhx15 and hrpA

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_415931.4
• Gene: hrpA / 948444
• ECOCYCID: G6732
• Length: 1300
• Species: Escherichia coli
• Alignment Length: 701
• Identity: 239/701 - (34%)
• Similarity: 388/701 - (55%)
• Gaps: 61/701 - (8%)

  Fly    12 YGSKAKKDPEASSSSAAAAAGTVAQILGGFVPNK--QPPTMNPLTNTPYSQRYQNLYKKRIALPV 74
            :|.|..|:|:|..:.....|..:.|..|..:..:  :|....| .|.|.||:.|
E. coli    32 HGVKKVKNPDAQQAIFQEMAKEIDQAAGKVLLREAARPEITYP-DNLPVSQKKQ----------- 84

  Fly    75 FEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWCVDFAVSKGRKG-VSCTQPRRVAAMSVAQRV 138
                 |.:..:..||.:::.||||||||||:|:.|::  :.:|.|| :..|||||:||.:||.|:
E. coli    85 -----DILEAIRDHQVVIVAGETGSGKTTQLPKICME--LGRGIKGLIGHTQPRRLAARTVANRI 142

  Fly   139 SEEMDVKLGEEVGYSIRFEDCSTAKTLLKYMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATD 203
            :||:..:.|..:||.:||.|..:..|::|.||||:||.|...|.:|.||..|::||||||:|..|
E. coli   143 AEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNID 207

  Fly   204 ILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQYFDNAPLMKVPGRTHPVEIFYTP------EPER 262
            .|:|.|||::.:|.|||:::.|||:|..:|.::|:|||:::|.|||:|||:.|.|      :.||
E. coli   208 FLLGYLKELLPRRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTER 272

  Fly   263 DYLEAAIRTVIQIHMCEEIEGDILMFLTGQEEIEEACKRIKREIDNLGSEIGELKCIPLYSTLPP 327
            |.|:|....|.:  :.:|..||||:|::|:.||.:....:.:      ..:...:.:|||:.|..
E. coli   273 DQLQAIFDAVDE--LSQESHGDILIFMSGEREIRDTADALNK------LNLRHTEILPLYARLSN 329

  Fly   328 NLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVS 392
            :.|.|:|:        ...||::|::||:||||||:.|:.:|||||.|:...|:.|.:|:.|.:.
E. coli   330 SEQNRVFQ--------SHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIE 386

  Fly   393 PISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVH 457
            |||:|||.||.||.||...|.|.|||:|..|.:. .:.|.|||||:||.:|:||:..||:.|:..
E. coli   387 PISQASANQRKGRCGRVSEGICIRLYSEDDFLSR-PEFTDPEILRTNLASVILQMTALGLGDIAA 450

  Fly   458 FDFMDPPAPETLMRALELLNYLAALDDDG-----NLTDLGAVMSEFPLDPQLAKMLIASCQHNCS 517
            |.|::.|....:...:.||..|.|:..|.     .||.||..:|:.|:||:||:|::.:.:|.|.
E. coli   451 FPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCV 515

  Fly   518 NEILSITAMLSVPQCFVRPNEAKKAADEAKMRFAHIDGDHLTLLNV--YHAFKQSSEDPN----W 576
            .|.:.||:.||:.....||.:.::|:||...||...:.|.|..:|:  |...:|.:...|    .
E. coli   516 REAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSNAFRRL 580

  Fly   577 CYENFINFRSLKSADNVRQQLARIMDRFNLRRTSTEFTSKDYYVNIRKALVQGFFMQVAHLERTG 641
            |..:::|:..::...::..||.:::....:...|.....::.::    ||:.|....:...:...
E. coli   581 CRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHI----ALLTGLLSHIGMKDADK 641

  Fly   642 YYLTIKDNQNVQLHPSTCLDHK-PDWVIYNEFVLTTKNYIRTVTDVKPEWL 691
            ...|...|....:.|.:.|..| |.||:..|.|.|::.:.|....:.|||:
E. coli   642 QEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWV 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	223/638 (35%)
hrpA	NP_415931.4	PRK11131	5..1298	CDD:182986	239/701 (34%)