Protein Alignment Dhx15 and ECM16

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_013847.1
• Gene: ECM16 / 855158
• SGDID: S000004735
• Length: 1267
• Species: Saccharomyces cerevisiae
• Alignment Length: 894
• Identity: 260/894 - (29%)
• Similarity: 400/894 - (44%)
• Gaps: 242/894 - (27%)

  Fly    61 RYQNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWCVDFAVS-------KGR 118
            |...:.|.||.||||..:...|..:..:..:::.||||||||||:||:..:....       .|.
Yeast   380 RSDEIQKARIQLPVFGEEHKIMEAIHHNDVVIICGETGSGKTTQVPQFLYEAGFGAEDSPDYPGM 444

  Fly   119 KGVSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLLKYMTDGMLLREAMSDPM 183
            .|:  ||||||||:|:|:||:.|:. ..|.:|||.|||:..:...|.:|:||||:||||.|.|..
Yeast   445 VGI--TQPRRVAAVSMAERVANELG-DHGHKVGYQIRFDSTAKEDTKVKFMTDGVLLREMMHDFK 506

  Fly   184 LDQYQVILLDEAHERTLATDILMGVLKEVIRQRS-----------DLKLVVMSATLDAGKFQQ-- 235
            |.:|..|::||||||.:.||||:|:|...:|.|:           .|||::|||||....|.:
Yeast   507 LTKYSSIIIDEAHERNINTDILIGMLSRCVRLRAKLHKENPIEHKKLKLIIMSATLRVSDFSENK 571

  Fly   236 -YFDNA-PLMKVPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEIEGDILMFLTGQEEIEEA 298
             .|..| |:::|..|..||.|.:......:|.:.|.|...:||. :...|.||:|||||:||...
Yeast   572 TLFPIAPPVLQVDARQFPVSIHFNRRTAFNYTDEAFRKTCKIHQ-KLPPGAILVFLTGQQEITHM 635

  Fly   299 CKRIKREI------------------------------------------DNLGSEI-------- 313
            .||:::|.                                          |...|.|
Yeast   636 VKRLRKEFPFKKNSKYNKDLETPVSKMGINSKTTDLEAEDIDFSVQVIDQDKFKSAIRYEEDEGN 700

  Fly   314 ---GE-----------------------LKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVV 352
               ||                       |..:||||.||...|.|:|:  .||..:    |..:|
Yeast   701 SGNGEDEEDEEEEGFEEVLTEGQTANDPLYVLPLYSLLPTKEQMRVFQ--KPPQGS----RLCIV 759

  Fly   353 STNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRL 417
            :||:|||||||.||.:|:|.|.:|::.||....|:|..|..:|||||.|||||||||.||.|:||
Yeast   760 ATNVAETSLTIPGVRYVVDSGRSKERKYNESNGVQSFEVGWVSKASANQRSGRAGRTGPGHCYRL 824

  Fly   418 YTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAAL 482
            |:...|:::.:..:.|||||..:.::|||:|.:.|.::::|.|..||....|.:|::||.||.||
Yeast   825 YSSAVFEHDFEQFSKPEILRMPVESIVLQMKSMAIHNIINFPFPTPPDRVALSKAIQLLQYLGAL 889

  Fly   483 DDDGNLTDLGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFV------------R 535
            |:...:|:.|..||.|||.|:.:|||:.|.:..|...|::|.:.|||...|:            :
Yeast   890 DNKEMITEDGKKMSLFPLSPRFSKMLLVSDEKACLPYIVAIVSALSVGDPFINEFELGINEISRK 954

  Fly   536 PNEAKKAAD-------------------------EAKMRFAHID--GDHLTLLNVYHAFKQSSED 573
            ||..:...|                         :::.:|:.:|  .|...||:|..|.....::
Yeast   955 PNPDENLDDKIREHDESTPGMDPELKKELRSKFYKSRSQFSKLDKFSDVFRLLSVVSAMDYVPKE 1019

  Fly   574 PNWCY--ENFINFRSLKSADNVRQQLARIMDRFNLRRTSTE-----FTSKDYYVNI--------- 622
            ....:  :||:..:.::....:|:||..|:.    ..||.|     ..::|...:|
Yeast  1020 QKEIFMKKNFLRGKLMEEIVKLRKQLMYIIK----SNTSKENIAVVIRNEDLKSDIPSVIQIKLL 1080

  Fly   623 RKALVQGFFMQVA------------HLERTGY----YLTIKDNQN-------VQLHPSTCLDH-- 662
            ::.:..||...||            ...||..    |:.:...:.       |.:||::.|::
Yeast  1081 KQMICAGFVDHVAVRADVLFPDDAKITNRTSIINIPYIPVLATRTPNIEDCFVYIHPTSILNNLG 1145

  Fly   663 --KPDWVIYNEFVL--TTKNYIRTVTDV------------------KP--------------EWL 691
              .|.:::|....|  ..|..:.|:.|:                  ||              |..
Yeast  1146 EMPPKYMLYYSLHLGGNNKTRMNTLCDIASTPLANIARKGLLLTYSKPLTGQGLKTVNLSPTERY 1210

  Fly   692 CCLAPQY-----------YDLNNFPQCEAKRQLELLQQRLETKQYQKGF 729
            |.:.|::           :|||.....:.|::.:....:..|:   |||
Yeast  1211 CYVVPRFGSTVDNDLKIGWDLNPIAVHQKKQKGQWTVIKFITR---KGF 1256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	246/833 (30%)
ECM16	NP_013847.1	HrpA	390..>940	CDD:441249	204/559 (36%)
		HA2	879..1006	CDD:461295	33/126 (26%)
		OB_NTP_bind	1080..1184	CDD:400182	17/103 (17%)