DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhx15 and AT1G26370

DIOPT Version :9

Sequence 1:	NP_001260766.1	Gene:	Dhx15 / 35654	FlyBaseID:	FBgn0033160	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_173961.3	Gene:	AT1G26370 / 839179	AraportID:	AT1G26370	Length:	717	Species:	Arabidopsis thaliana

Alignment Length:	721	Identity:	293/721 - (40%)
Similarity:	431/721 - (59%)	Gaps:	75/721 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 LGGFVPNKQPPTMNPLTNTPYSQRYQNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKT 102
            |..||.|.:|...:| |.:|:|.| |.:.:.|.:||:...:...:..:..:..:::|||||||||
plant     9 LKSFVQNSRPNPKSP-TVSPFSMR-QKIAEHRRSLPIASVEKRLVEEVQKNDILIIVGETGSGKT 71

  Fly   103 TQIPQWCVDFAVSKGRKGVSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLLK 167
            ||:||:..:....:..|.:..|||||:||::||:||:||.:|:||::|||||||:|.::..|.||
plant    72 TQLPQFLYNAGFCREGKMIGITQPRRIAAVTVAKRVAEECEVQLGQKVGYSIRFDDTTSGSTRLK 136

  Fly   168 YMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSD-------------- 218
            |||||:|||||:.||.|.:|.||::||||:|::.||:|:.:||::.|.||.
plant   137 YMTDGLLLREALLDPHLSRYSVIIVDEAHDRSVHTDVLLALLKKIQRTRSQPVSEKTEFGNVASQ 201

  Fly   219 ---------------------------LKLVVMSATLDAGKFQQYFDNAPLMKVPGRTHPVEIFY 256
                                       |||::|||:|||..|.:||..|..:.|.||..||:|.|
plant   202 VQTTTRDANGPQQNGVLKGYQGRKLSPLKLIIMSASLDARVFSEYFGGAKAVHVQGRQFPVDILY 266

  Fly   257 TPEPERDYLEAAIRTVIQIHMCEEIEGDILMFLTGQEEIEEACKRIKREIDNLGSEIGELKCIPL 321
            |..||.||::|.:.|:.|||. ||..||||:|||||:|||...:.::..:.|:..:..:|..:.:
plant   267 TVHPESDYVDATLVTIFQIHF-EEKPGDILVFLTGQDEIESVERLVQERLQNIPEDKRKLLPLAI 330

  Fly   322 YSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRV 386
            :|.||...|.::|.|||    .|.  |||:::|||||||:||.|:.:||||||.|.:.|:|...:
plant   331 FSALPSEQQMKVFAPAP----TGF--RKVILATNIAETSITIPGIRYVIDPGFVKARSYDPSKGM 389

  Fly   387 ESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLG 451
            |||.|.|.|||...||||||||..|||.||||.|:.|: :::|:|.|||.|.||..::||||.||
plant   390 ESLDVVPASKAQTLQRSGRAGREGPGKSFRLYPEREFE-KLEDSTKPEIKRCNLSNIILQLKALG 453

  Fly   452 IDDLVHFDFMDPPAPETLMRALELLNYLAALDDDGNLTD-LGAVMSEFPLDPQLAKMLIASCQHN 515
            |||:|.|||:|.|:...:::||..|:.|.||.|||.|.: :|..||..||:|..:|.||.:.|.|
plant   454 IDDIVGFDFIDKPSRGAIIKALAELHSLGALADDGKLENPVGYQMSRLPLEPVYSKALILANQFN 518

  Fly   516 CSNEILSITAMLSVPQCFVRPNEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQSSED------- 573
            |..|:|...|:|||...|..|.|.::.|..:|..||.::|||||.|:||....:..|.
plant   519 CLEEMLITVAVLSVESIFYDPREKREEARTSKNHFASVEGDHLTYLSVYRESDEFLEKRKAAGSG 583

  Fly   574 -------PNWCYENFINFRSLKSADNVRQQLARIMDR--FNLRRTSTEFTSKDYYVNIRKALVQG 629
                   ..||.||::|.||||.|.::.:|:...:::  ||:.....:..:      .|:.|...
plant   584 NNIDKIMKKWCKENYVNSRSLKHARDIYRQIREHVEQIGFNVSSCGNDMLA------FRRCLAAS 642

  Fly   630 FFMQVAHLERTGYYLTIKDNQNVQLHPSTCLDH-KPDWVIYNEFVLTTKNYIRTVTDVKPEWLCC 693
            ||::.|..:..|.|..::..:.|.:||::.|.. ||:.||:||.:.|:|.||:.:|.:...||..
plant   643 FFLKAAQRQLDGTYRALESGEVVHIHPTSVLFRAKPECVIFNELMQTSKKYIKNLTIIDSLWLSE 707

  Fly   694 LAPQYY 699
            |||.::
plant   708 LAPHHF 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_001260766.1	Motor_domain	50..>102	CDD:277568	16/51 (31%)
		DEXDc	67..255	CDD:214692	91/228 (40%)
		DEXDc	91..228	CDD:238005	76/177 (43%)
		HELICc	315..408	CDD:197757	46/92 (50%)
		HA2	478..561	CDD:214852	37/83 (45%)
		OB_NTP_bind	595..698	CDD:285018	30/105 (29%)
AT1G26370	NP_173961.3	HrpA	31..714	CDD:224557	284/698 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53574
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730