DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhx15 and EMB3011

DIOPT Version :9

Sequence 1:	NP_001260766.1	Gene:	Dhx15 / 35654	FlyBaseID:	FBgn0033160	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_196805.2	Gene:	EMB3011 / 831141	AraportID:	AT5G13010	Length:	1255	Species:	Arabidopsis thaliana

Alignment Length:	676	Identity:	305/676 - (45%)
Similarity:	449/676 - (66%)	Gaps:	32/676 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 QNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWCVD--FAVSKGRKG-VSCT 124
            :.:.::|..||:|..:.:.::::..:|.||:|||||||||||:.|:..:  :.::    | |.||
plant   549 KTMAEQRQYLPIFSVRDELLQVIRENQVIVVVGETGSGKTTQLTQYLHEDGYTIN----GIVGCT 609

  Fly   125 QPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLLKYMTDGMLLREAMSDPMLDQYQV 189
            |||||||||||:||||||:.:||:::||:|||||.:...|::||||||:||||.:.|..||:|:|
plant   610 QPRRVAAMSVAKRVSEEMETELGDKIGYAIRFEDVTGPNTVIKYMTDGVLLRETLKDSDLDKYRV 674

  Fly   190 ILLDEAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQYFDNAPLMKVPGRTHPVEI 254
            :::||||||:|.||:|.|:||:|:.:|.|.||:|.||||:|.||..:|.:.|:..:||||.||.|
plant   675 VVMDEAHERSLNTDVLFGILKKVVARRRDFKLIVTSATLNAQKFSNFFGSVPIFNIPGRTFPVNI 739

  Fly   255 FYTPEPERDYLEAAIRTVIQIHMCEEIEGDILMFLTGQEEIEEACKRIKREIDNLGS----EIGE 315
            .|:..|..||:|||::..:.||:... .||||:|:|||:|||.||..:|..::.|.|    ||..
plant   740 LYSKTPCEDYVEAAVKQAMTIHITSP-PGDILIFMTGQDEIEAACFSLKERMEQLVSSSSREITN 803

  Fly   316 LKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVY 380
            |..:|:||.||.:||.:||:..    .:||  ||.:|:|||||||||:||:.:|||.|:.|.||:
plant   804 LLILPIYSQLPADLQAKIFQKP----EDGA--RKCIVATNIAETSLTVDGIYYVIDTGYGKMKVF 862

  Fly   381 NPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGTVVL 445
            |||:.:::|.|.|||:|::.||:||||||.||.|:|||||.|:.|||..:..|||.|:|||.|||
plant   863 NPRMGMDALQVFPISRAASDQRAGRAGRTGPGTCYRLYTESAYLNEMLPSPVPEIQRTNLGNVVL 927

  Fly   446 QLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALDDDGNLTDLGAVMSEFPLDPQLAKMLIA 510
            .||.|.||:|:.|||||||..|.::.::..|..|.||::.|.|||||..|.||||||.|||||:.
plant   928 LLKSLKIDNLLDFDFMDPPPQENILNSMYQLWVLGALNNVGGLTDLGWKMVEFPLDPPLAKMLLM 992

  Fly   511 SCQHNCSNEILSITAMLSVPQCFVRPNEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQSSEDPN 575
            ..:.:|.:|:|:|.:|||||..|.||.|..:.:|.|:.:|...:.|||||||||..:|:.....:
plant   993 GERLDCIDEVLTIVSMLSVPSVFFRPKERAEESDAAREKFFVPESDHLTLLNVYQQWKEHDYRGD 1057

  Fly   576 WCYENFINFRSLKSADNVRQQLARIMDRFNLRRTSTEFTSKDYYVNIRKALVQGFFMQVAHLERT 640
            ||.::::..:.|:.|..||.||..|:.:..:...|   ...|:.: :|||:...:|...|.|:..
plant  1058 WCNDHYLQVKGLRKAREVRSQLLDILKQLKIELRS---CGPDWDI-VRKAICSAYFHNSARLKGV 1118

  Fly   641 GYYLTIKDNQNVQLHPSTC---LDHKPDWVIYNEFVLTTKNYIRTVTDVKPEWLCCLAPQYYDLN 702
            |.|:..:......||||:.   |.:.||:|:|:|.:||||.|::..|.|:|.||..|.|.::.:.
plant  1119 GEYVNCRTGMPCHLHPSSALYGLGYTPDYVVYHELILTTKEYMQCATSVEPHWLAELGPMFFSVK 1183

  Fly   703 NFPQCEAKRQLELLQQRLETKQYQKG 728
            :       ....:|:.:.:.|:.:.|
plant  1184 D-------SDTSMLEHKKKQKEEKSG 1202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_001260766.1	Motor_domain	50..>102	CDD:277568	14/38 (37%)
		DEXDc	67..255	CDD:214692	99/190 (52%)
		DEXDc	91..228	CDD:238005	81/139 (58%)
		HELICc	315..408	CDD:197757	47/92 (51%)
		HA2	478..561	CDD:214852	41/82 (50%)
		OB_NTP_bind	595..698	CDD:285018	35/105 (33%)
EMB3011	NP_196805.2	DUF1777	158..>247	CDD:285811
		DEXDc	553..739	CDD:214692	99/189 (52%)
		DEXDc	575..713	CDD:238005	82/141 (58%)
		HELICc	806..892	CDD:197757	48/91 (53%)
		HA2	961..1043	CDD:214852	41/81 (51%)
		OB_NTP_bind	1077..1177	CDD:285018	34/103 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X141
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720