DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhx15 and AT4G16680

DIOPT Version :9

Sequence 1:	NP_001260766.1	Gene:	Dhx15 / 35654	FlyBaseID:	FBgn0033160	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001329688.1	Gene:	AT4G16680 / 827370	AraportID:	AT4G16680	Length:	796	Species:	Arabidopsis thaliana

Alignment Length:	764	Identity:	354/764 - (46%)
Similarity:	487/764 - (63%)	Gaps:	70/764 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KRRIEVG-ETY-----------GSKAKKDPEASSSSAAAAAGTVAQI----------LGGFVPNK 45
            |:|.:|. |.|           ..:|.:|.:|..:.....|....|:          |.|||..
plant    44 KKRFDVAKERYCERRRSGRVVTEQEAWEDHQAQKARVRFGAKDKKQVVDGYEFVFDDLTGFVEE- 107

  Fly    46 QPPTMNPLTNTPYSQRYQNLYKKRIA---------LPVFEYQADFMRLLSLHQCIVLVGETGSGK 101
                    ::...:.:::..|.|..|         ||:..|:.:.::|:..:|.:|:||||||||
plant   108 --------SSEAETGKHRGCYSKTAAEKAREGREFLPIHGYREELLKLIEENQVLVIVGETGSGK 164

  Fly   102 TTQIPQWCVDFAVSKGRKGVSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLL 166
            ||||||:..:...:| |..:.|||||||||||||.||::|:.||||.|||||||||||::.||::
plant   165 TTQIPQYLQEAGYTK-RGKIGCTQPRRVAAMSVASRVAQEVGVKLGHEVGYSIRFEDCTSEKTVI 228

  Fly   167 KYMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAG 231
            |||||||||||.:.:|.||.|.||::||||||||:||||..::|:|.:.|.||:|::.||||:|.
plant   229 KYMTDGMLLRELLIEPKLDSYSVIIIDEAHERTLSTDILFALVKDVAKVRPDLRLIISSATLEAK 293

  Fly   232 KFQQYFDNAPLMKVPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEIEGDILMFLTGQEEIE 296
            ||.:|||:|.:..:|||.:|||..:...||.||||..||||:|||..|.| ||||:|||||||||
plant   294 KFSEYFDSARIYLIPGRRYPVEKLFRKCPEPDYLETVIRTVVQIHQTEAI-GDILVFLTGQEEIE 357

  Fly   297 EACKRIKREIDNLGSEIGELKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSL 361
            .....:||.:.:||::..|:...|:||.||..||.::|||||...      ||||::||||||||
plant   358 TVETNLKRRMMDLGTKGSEIIICPIYSNLPTPLQAKVFEPAPKGT------RKVVLATNIAETSL 416

  Fly   362 TIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNE 426
            |||||.:|||||:.|...||||..:|||||:|||||||.||:||:|||.||||||||..|    :
plant   417 TIDGVKYVIDPGYCKINSYNPRTGMESLLVTPISKASAAQRAGRSGRTGPGKCFRLYNIK----D 477

  Fly   427 MQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALDDDGNLTDL 491
            ::..|.|||.|:||.:|||.||.|||.|:.:|||||||....|::|||||..|.|||:.|.:|.:
plant   478 LEPTTIPEIQRANLASVVLTLKSLGIQDVFNFDFMDPPPENALLKALELLYALGALDEIGEITKV 542

  Fly   492 GAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSV-PQCFVRPNEAKKAADEAKMRFAHID- 554
            |..|.|||:||.|:||::.|.::.||.||::|.||||| ...|.||...:..||:|:|.| :.|
plant   543 GERMVEFPVDPMLSKMIVGSEKYKCSKEIITIAAMLSVGNSVFYRPKNQQVFADKARMDF-YEDT 606

  Fly   555 ---GDHLTLLNVYHAFKQSSEDPNWCYENFINFRSLKSADNVRQQLARIMDRFNLRRTSTEFTSK 616
               |||:.||.||:::|:.:....||.|.||..:|:|.|.::|.||..::::..:     |.||.
plant   607 ENVGDHIALLRVYNSWKEENYSTQWCCEKFIQSKSMKRARDIRDQLLGLLNKIGV-----ELTSN 666

  Fly   617 DYYVN-IRKALVQGFFMQVAHLERTGYYLTIKDNQNVQLHPSTCL-DHKPD-WVIYNEFVLTTKN 678
            ...:: |:||::.|||...|.|::.|.|..:|:.|.|.:||::.| ...|. |::|:|.|||||.
plant   667 PNDLDAIKKAILAGFFPHSAKLQKNGSYRRVKEPQTVYVHPNSGLFGASPSKWLVYHELVLTTKE 731

  Fly   679 YIRTVTDVKPEWLCCLAPQYYDLNNFPQCEAKRQLELLQQRLETKQYQK 727
            |:|..|::|||||..:||.||.|.:......|:    .|:|:|.....|
plant   732 YMRHTTEMKPEWLIEIAPHYYKLKDIEDTRPKK----TQRRIEEASTSK 776

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_001260766.1	Motor_domain	50..>102	CDD:277568	16/60 (27%)
		DEXDc	67..255	CDD:214692	109/196 (56%)
		DEXDc	91..228	CDD:238005	87/136 (64%)
		HELICc	315..408	CDD:197757	56/92 (61%)
		HA2	478..561	CDD:214852	39/87 (45%)
		OB_NTP_bind	595..698	CDD:285018	40/105 (38%)
AT4G16680	NP_001329688.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53574
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X141
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.730