Protein Alignment Dhx15 and Tdrd9

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_083332.1
• Gene: Tdrd9 / 74691
• MGIID: 1921941
• Length: 1383
• Species: Mus musculus
• Alignment Length: 660
• Identity: 181/660 - (27%)
• Similarity: 305/660 - (46%)
• Gaps: 128/660 - (19%)

  Fly    37 ILGGFVPNKQPPTMNPLT---------NTPYSQRYQNLYKKRIALPVFEYQADFMRLLSLHQCIV 92
            |.|...|...|...:||.         .|.|  :|.:       ||:...:.:.:.|:..:..::
Mouse    99 IYGQDQPPSGPGLRSPLAKLSNVACIPETTY--KYPD-------LPINRCKEEVISLIESNSVVI 154

  Fly    93 LVGETGSGKTTQIPQWCVDFAVSKGR-KGVSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRF 156
            :.|.|||||:||:||:.:|....:.. ..:..||||::.|.|:|:.:|:|....||..|||.:..
Mouse   155 IHGATGSGKSTQLPQYVLDHYTQRSAFCNIVVTQPRKIGASSIARWISKERSWTLGGLVGYQVGL 219

  Fly   157 EDCSTAKTLLKYMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSD-LK 220
            |..:|..|.|.|||.|:||::.:|...|.::..|.:||.||||...|.|:.|:::::|..|. :|
Mouse   220 EKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTHIFIDEVHERTEEMDFLLLVVRKLLRTNSRFVK 284

  Fly   221 LVVMSATLDAGKFQQYF--------DNAPLMKVPGRTHPVEIFY-----------------TPEP 260
            :|:||||::..:|..||        :.|.:.:|.|:.|.:|.:|                 .|..
Mouse   285 VVLMSATINCKQFADYFAVPVQNKMNPAYVFEVEGKPHAIEEYYLNDLGHIYHSGLPYRLEEPVI 349

  Fly   261 ERDYLEAAIRTVIQIHMCEEIE------------------GDILMFLTGQEEIEEACKRIKREID 307
            .:|..|.|:..   |.|.::::                  ..:|:||.|..||....:.:...|.
Mouse   350 TKDVYEVAVSL---IQMFDDLDMKESGNKTWSGAQFVSERSSVLVFLPGLGEINYMHELLTNMIH 411

  Fly   308 NLGSEIGELKCIPLYSTLPPNLQQRIF-EPAPPPNANGAIG-RKVVVSTNIAETSLTIDGVVFVI 370
            .      .|:..||:|::....|..:| .|.|        | ||:::||||||:|:|:..|.:||
Mouse   412 K------RLQVYPLHSSVTLEEQNNVFLSPVP--------GYRKIILSTNIAESSVTVPDVKYVI 462

  Fly   371 DPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEI 435
            |....:..|.:.....:||.:|..||.|..||.|||||...|.|:||.....:.:.:.|:..||:
Mouse   463 DFCLTRTLVCDEDTNYQSLRLSWASKTSCDQRKGRAGRVSKGYCYRLIPRDFWDSAIPDHVVPEM 527

  Fly   436 LRSNLGTVVLQLKKLGIDD--LVHFDFMDPPAPETLMRALELLNYLAAL-------DD---DGNL 488
            ||..||:.:|::|.|.:.:  .:....:.||:...:.|.:.||..:.||       |:   ||.|
Mouse   528 LRCPLGSTILKVKLLDMGEPRALLATALSPPSLSDIERTILLLKEVGALAVSGQREDENPHDGEL 592

  Fly   489 TDLGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFVRPNEAKKAADEAKMRFAHI 553
            |.||.|:::.|:..||.|:::......|.:|.|.|.|.||:...|..|..            .|:
Mouse   593 TFLGRVLAQLPVSQQLGKLVVLGHVFGCLDECLIIAAALSLKNFFTMPFR------------QHL 645

  Fly   554 DG-------------DHLTLLNVYHAF---------KQSSEDPNWCYENFINFRSLKSADNVRQQ 596
            ||             |.|.|:..:.|:         ::..::.:|...|:|..:.::....:.::
Mouse   646 DGYRNKVHFSGSSRSDCLALVEAFRAWQACRQRGELRRPKDELDWGRLNYIQIKRIREVAELYEE 710

  Fly   597 LARIMDRFNL 606
            |...:.:||:
Mouse   711 LKNRISQFNM 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	172/617 (28%)
Tdrd9	NP_083332.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..82
		HrpA	132..>706	CDD:441249	169/609 (28%)
		DEAD-like_helicase_N	134..317	CDD:475120	62/182 (34%)
		DEAH box. /evidence=ECO:0000269|PubMed:28633017	256..259		2/2 (100%)
		Tudor_TDRD9	906..1006	CDD:410502