Protein Alignment Dhx15 and dhx8

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: XP_002932570.2
• Gene: dhx8 / 733563
• XenbaseID: XB-GENE-6087171
• Length: 1181
• Species: Xenopus tropicalis
• Alignment Length: 708
• Identity: 349/708 - (49%)
• Similarity: 484/708 - (68%)
• Gaps: 28/708 - (3%)

  Fly    20 PEASSSSAAAAAGTVAQILGGFVPNKQPPTMNPL---TNTPYSQRYQ-NLYKKRIALPVFEYQAD 80
            |:|.....||....:     |.:||..|......   ....|.::.| ::.::|.:||:::.:..
 Frog   475 PDADGRQIAANMRGI-----GMMPNDIPEWKKHAFGGNKASYGKKTQMSIVEQRESLPIYKLKEQ 534

  Fly    81 FMRLLSLHQCIVLVGETGSGKTTQIPQWCVDFA-VSKGRKGVSCTQPRRVAAMSVAQRVSEEMDV 144
            .::.:..:|.::::|||||||||||.|:..:.. .::|:  :.|||||||||||||:|||||...
 Frog   535 LVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGK--IGCTQPRRVAAMSVAKRVSEEYGC 597

  Fly   145 KLGEEVGYSIRFEDCSTAKTLLKYMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVL 209
            .||:||||:||||||::.:|::|||||||||||.:.||.|.||.:|:||||||||:.||:|.|:|
 Frog   598 CLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLL 662

  Fly   210 KEVIRQRSDLKLVVMSATLDAGKFQQYFDNAPLMKVPGRTHPVEIFYTPEPERDYLEAAIRTVIQ 274
            |:.:::|.|:||:|.||||||.||.|||..||:..:||||:||||.||.|||.|||:|::.||:|
 Frog   663 KKTVQKRPDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQ 727

  Fly   275 IHMCEEIEGDILMFLTGQEEIEEACKRIKREIDNLGSEIGELKCIPLYSTLPPNLQQRIFEPAPP 339
            ||:.|. .||||:||||||||:.||:.:...:.:||.::.||..:|:||.||..:|.|||:||||
 Frog   728 IHLTEP-PGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPP 791

  Fly   340 PNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSG 404
            .:      ||||::||||||||||||:.:|:||||.||||||.:..::.|:|:|||:|.|:||:|
 Frog   792 GS------RKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAG 850

  Fly   405 RAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETL 469
            |||||.||||:|||||:|:::||.....|||.|:||.:.||.||.:||:||:.|||||.|..|||
 Frog   851 RAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETL 915

  Fly   470 MRALELLNYLAALDDDGNLTDLGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFV 534
            :.|:|.|..|.||||:|.||.||..|:||||:|.|.||||.|....||.|:|:|.:||||...|.
 Frog   916 ITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFY 980

  Fly   535 RPNEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQSSEDPNWCYENFINFRSLKSADNVRQQLAR 599
            ||.:.:..||:.|.:|...:|||||||.||:::|.:.....|||||||..|||:.|.::|:|:..
 Frog   981 RPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLG 1045

  Fly   600 IMDRFNLRRTSTEFTSKDYYVNIRKALVQGFFMQVAHLERTGYYLTIKDNQNVQLHPSTCL-DHK 663
            ||||..|...|....:    |.::||:..|||...|..:....|.|:.|.|.|.:|||:.| :.:
 Frog  1046 IMDRHKLDVVSCGKAT----VRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQ 1106

  Fly   664 PDWVIYNEFVLTTKNYIRTVTDVKPEWLCCLAPQYYDLNNFPQCEAKRQLELLQQRLE 721
            |:||:|:|.|||||.|:|.||.:.|.||...||.::.:::    ..|...:..|||||
 Frog  1107 PEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSD----PTKLSKQKKQQRLE 1160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	328/621 (53%)
dhx8	XP_002932570.2	GH2-like_DHX8	12..79	CDD:409668
		S1_DHX8_helicase	226..304	CDD:240189
		HrpA	517..>1148	CDD:441249	333/647 (51%)