Protein Alignment Dhx15 and Dhx35

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_001359442.1
• Gene: Dhx35 / 71715
• MGIID: 1918965
• Length: 703
• Species: Mus musculus
• Alignment Length: 687
• Identity: 305/687 - (44%)
• Similarity: 440/687 - (64%)
• Gaps: 35/687 - (5%)

  Fly    45 KQPPTMNPLTN---TPYSQRYQNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIP 106
            :|..|.|..|.   .||:.  .::.::|..||||:.:...:.|:..:|.:|:|||||.||:||||
Mouse    26 RQSVTENSGTTIIYNPYAA--LSIEQQRQKLPVFKLRNHILYLVENYQTVVIVGETGCGKSTQIP 88

  Fly   107 QWCVDFAVSKGRKGVSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCS-TAKTLLKYMT 170
            |:..:...:...:.|..||||||||::||.||::|....||.||||.|||:||: ...|.:|::|
Mouse    89 QYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGHEVGYCIRFDDCTDPLATRIKFLT 153

  Fly   171 DGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQ 235
            ||||:||.|.||:|.:|.||:|||||||||.|||.:|:||::.::|.||:|:|.||||||.||:.
Mouse   154 DGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRD 218

  Fly   236 YF----------DNAPLMKVPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEIEGDILMFLT 290
            :|          |.:..:.|.|||.||:|||...|..||::|.:.||::||..|. :||||.|||
Mouse   219 FFNQNETSDPARDTSVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEG-DGDILAFLT 282

  Fly   291 GQEEIEEACKRI---KREIDNLGSEIGELKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVV 352
            ||||:|.....:   .|.:...|.: ..|:.:|:|:.||...|.::||     ..:.:: |||:|
Mouse   283 GQEEVETVVSMLIEQARALARTGMK-KHLRVLPMYAGLPSFEQMKVFE-----RVSHSV-RKVIV 340

  Fly   353 STNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRL 417
            :||:||||:||.|:|:|||.||.|.:.||||..:|.|:|.|:|:|||.||:||.||.|.|||:||
Mouse   341 ATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRL 405

  Fly   418 YTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAAL 482
            |||:|| :::..:|.||:.||||..|:||||.||||:::.|.||.||..:::::|||||..|..|
Mouse   406 YTEEAF-DQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGL 469

  Fly   483 DDDGNLTD-LGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFVRPNEAKKAADEA 546
            |.|..||: ||..::||||:|..||||:.|....||.|:|||.||:.:...||.|:..|..|...
Mouse   470 DKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQNVFVFPSNQKSQATRV 534

  Fly   547 KMRFAHIDGDHLTLLNVYHAFKQSSEDPNWCYENFINFRSLKSADNVRQQLARIMDRFNLRRTST 611
            ..:||..:|||||:||||.||.:.::...||.|:|:|::.|..|..||.||.:::.:|.:.:.|:
Mouse   535 HRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVRDQLKKLLVKFQVPKVSS 599

  Fly   612 EFTSKDYYVNIRKALVQGFFMQVAHLERTGYYLTIKDNQNVQLHPSTCL--DHKPDWVIYNEFVL 674
            |.....    :.:.:|.|||...|....:|.|.||:|:..:.:||::.|  :..|.||||||.:.
Mouse   600 EGDPDP----VLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQ 660

  Fly   675 TTKNYIRTVTDVKPEWLCCLAPQYYDLNNFPQCEAKR 711
            |:|.|:|.||.::..||..|||.:|........:|||
Mouse   661 TSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKR 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	289/636 (45%)
Dhx35	NP_001359442.1	HrpA	54..>701	CDD:441249	298/657 (45%)