Protein Alignment Dhx15 and Dhx38

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_848467.1
• Gene: Dhx38 / 64340
• MGIID: 1927617
• Length: 1228
• Species: Mus musculus
• Alignment Length: 736
• Identity: 313/736 - (42%)
• Similarity: 468/736 - (63%)
• Gaps: 43/736 - (5%)

  Fly     7 EVGETYGSKAKKDPEASSSSAAAAAGTVAQILGGFVPNKQPPTMNPLTNTPYSQRYQNLYKKRIA 71
            ::|:..|.|.:::|:.:.:..........|.....:..|..      .::.:::: :::.::|..
Mouse   475 KLGDIMGVKKEEEPDKAMTEDGKVDYRTEQKFADHMKEKSE------ASSEFAKK-KSILEQRQY 532

  Fly    72 LPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWC-----VDFAVSKGRKGVSCTQPRRVAA 131
            ||:|..|.:.:.::..:..:::|||||||||||:.|:.     .|:.:      :.|||||||||
Mouse   533 LPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGM------IGCTQPRRVAA 591

  Fly   132 MSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLLKYMTDGMLLREAMSDPMLDQYQVILLDEAH 196
            ||||:||||||...|||||||:||||||::..||:||||||:||||::.:..||.|..:::||||
Mouse   592 MSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAVIMDEAH 656

  Fly   197 ERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQYFDNAPLMKVPGRTHPVEIFYTPEPE 261
            ||:|.||:|.|:|:||:.:||||||:|.|||:||.||..:|.|.|:..:||||.||:|.::..|:
Mouse   657 ERSLNTDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ 721

  Fly   262 RDYLEAAIRTVIQIHMCEEIEGDILMFLTGQEEIEEACKRIKREIDNLGSEIGELKCIPLYSTLP 326
            .||:|||::..:|:|: ....||||:|:.|||:||....:|...::.| .....|..:|:||.||
Mouse   722 EDYVEAAVKQSLQVHL-SGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLP 784

  Fly   327 PNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLV 391
            .:||.:||:.||    :|.  ||.:|:|||||||||:||::||||.|:.|.||:||||.:::|.:
Mouse   785 SDLQAKIFQKAP----DGV--RKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQI 843

  Fly   392 SPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLV 456
            .|||:|:|.|||||||||.||:||||||:.|:|||:...|.|||.|:||..|||.||.||:.||:
Mouse   844 YPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLL 908

  Fly   457 HFDFMDPPAPETLMRALELLNYLAALDDDGNLTDLGAVMSEFPLDPQLAKMLIASCQHNCSNEIL 521
            .|.|||||..:.::.::..|..|.|||:.|.||..|.:|.||||||.|:||||.||...||:|||
Mouse   909 QFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEIL 973

  Fly   522 SITAMLSVPQCFVRPNEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQSSEDPNWCYENFINFRS 586
            .|.:|||||..|.||...::.:|:.:.:||..:.||||.||||..:|.::....||.::||:.::
Mouse   974 LIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKA 1038

  Fly   587 LKSADNVRQQLARIM--DRFNLRRTSTEFTSKDYYVNIRKALVQGFFMQVAHLERTGYYLTIKDN 649
            ::....||.||..||  .|.:|....|::..      :||.:...:|.|.|.|:..|.|:.|:..
Mouse  1039 MRKVREVRAQLKDIMVQQRMSLASCGTDWDI------VRKCICAAYFHQAAKLKGIGEYVNIRTG 1097

  Fly   650 QNVQLHPSTCL---DHKPDWVIYNEFVLTTKNYIRTVTDVKPEWLCCLAPQYYDLNNFPQC---- 707
            ....|||::.|   .:.||:::|:|.|:|||.|::.||.|..|||..|.|.:|.:....:.
Mouse  1098 MPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVKQAGKSRQEN 1162

  Fly   708 --EAKRQLELLQQRLETKQYQ 726
              .||.:...:::.:...:.|
Mouse  1163 RRRAKEEASAMEEEMALAEEQ 1183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	298/629 (47%)
Dhx38	NP_848467.1	HrpA	533..>1147	CDD:441249	301/633 (48%)