DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhx15 and Zcchc17

DIOPT Version :9

Sequence 1:	NP_001260766.1	Gene:	Dhx15 / 35654	FlyBaseID:	FBgn0033160	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_694800.1	Gene:	Zcchc17 / 619605	MGIID:	1919955	Length:	241	Species:	Mus musculus

Alignment Length:	157	Identity:	36/157 - (22%)
Similarity:	59/157 - (37%)	Gaps:	34/157 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 GELKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAK-- 376
            ||:..:..|..         |...|.....|.:.|..:.|..:.:.|..:|    |.|..:.|
Mouse    21 GEVAMVTDYGA---------FIKIPGCRKQGLVHRTHMSSCRVDKPSEIVD----VGDKVWVKLI 72

  Fly   377 -QKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEI-LRSN 439
             :::.|.||:| ||.:..:::.:        |:........:..|:..:...||.|..:| |.:.
Mouse    73 GREMKNDRIKV-SLSMKVVNQGT--------GKDLDPNNVVIEQEERRRRSFQDYTGQKITLEAV 128

  Fly   440 LGTVVLQLKKLGIDDLVHFD---FMDP 463
            |.|.   .||.|...  ||.   ||.|
Mouse   129 LNTT---CKKCGCKG--HFAKDCFMQP 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_001260766.1	Motor_domain	50..>102	CDD:277568
		DEXDc	67..255	CDD:214692
		DEXDc	91..228	CDD:238005
		HELICc	315..408	CDD:197757	18/95 (19%)
		HA2	478..561	CDD:214852
		OB_NTP_bind	595..698	CDD:285018
Zcchc17	NP_694800.1	S1_pNO40	13..86	CDD:240191	18/78 (23%)
Zcchc17	NP_694800.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	160..241
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900