Protein Alignment Dhx15 and spn-E

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Alignment Length: 753
• Identity: 203/753 - (26%)
• Similarity: 331/753 - (43%)
• Gaps: 141/753 - (18%)

  Fly    37 ILGGFVPNKQPP-----TMNPLTNTPYSQ----RYQNLYKKRIA--------LPVFEYQADFMRL 84
            :|.|.:.|:||.     |::.|......:    |..:.|.|:..        |.::..:.:.:..
  Fly    63 LLNGTLLNEQPQGKRIRTLDDLDTDDEGEETEIRRDDEYYKKFRFNLNRDKNLSIYAKREEILAA 127

  Fly    85 LSLHQCIVLVGETGSGKTTQIPQWCVDFAVSKGRK-GVSCTQPRRVAAMSVAQRVSEEMDVKLGE 148
            ::.|..:::.||||.|||||:||:.:|.|...|:. .:..|||||:||:|:|.||.:|.:.:...
  Fly   128 INAHPVVIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAISIANRVCQEREWQQNT 192

  Fly   149 EVGYSI------RFEDCSTAKTLLKYMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMG 207
            ...:.:      ..||     |.|.|.|.|:||...:::..|..|..|:|||.|||....|.|:.
  Fly   193 VCSFQVGLHRPNSLED-----TRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLI 252

  Fly   208 VLKEVIRQRS-DLKLVVMSATLDAGKFQQYFDNA----PLMKV-PGRTHPVEIFY---------- 256
            |::.::...| .:|:::||||:||.:...||...    |::.. ..|.|.:|.||
  Fly   253 VVRRLLATNSRHVKIILMSATIDAKELSDYFTTTNSIPPVITTNHRRKHSIEKFYRDQLGSIIWN 317

  Fly   257 --------TPEPERDYLEAAIRTVIQIHMCEE---IE-----------GDILMFLTGQEEIEEAC 299
                    .||..:....||::.::.|...|.   |:           |.:|:||.|..||:...
  Fly   318 EEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAIQSRQSYDEALRYGAVLIFLPGIYEIDTMA 382

  Fly   300 KRIKREIDN-LGSEIGELKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTI 363
            :.:...::| ...::..::|   :|.:.|..|:.:|.| |||..     ||::::|||||:|:|:
  Fly   383 ENLTCMLENDPNIKVSIVRC---FSLMTPENQRDVFNP-PPPGF-----RKIILTTNIAESSITV 438

  Fly   364 DGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQ 428
            ..|.:|||...||.||.:......||.::..|||:.:||:||.||.|.|:.:|:..:..::.||.
  Fly   439 PDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNKHFYQREMP 503

  Fly   429 DNTYPEILRSNLGTVVLQLKKLGIDDLVHF--DFMDPPAPETLMRALELLNYLAAL--------D 483
            :...||:||..|...||:.|.|.:...|..  ..:.||....:...:.||..:.||        |
  Fly   504 EFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPNLSDIHNTILLLKEVGALYLTVDGIYD 568

  Fly   484 D-DGNLTDLGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFVRPNEAKKAADEAK 547
            . ||:||..|.:||..|||.:.::::|.....|...|.:.|.|.||.|..|.......:..|...
  Fly   569 PLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAGLSTPGLFAHEGGRSQLGDSFW 633

  Fly   548 MRFAHIDGD----------HLTLLNVYHAFKQSSEDPNWCYENFINFRSLKSADNVRQQLARIMD 602
            |.:...||.          :||.||:............|.....::.||||....:.|:
  Fly   634 MHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQESAIRWAKRFHVSLRSLKEIHLLVQE------ 692

  Fly   603 RFNLRRTSTEFTSKDYYVN------------IRKALVQGFFMQVAHLERTGYYLTIKDNQNVQLH 655
               ||...|......:.||            :.|.::.|.|.       ..|:...|:
  Fly   693 ---LRVRCTHLGLIPFPVNPNQMMDDREKAIMLKVIIAGAFY-------PNYFTRSKE------- 740

  Fly   656 PSTCLDHKPDWVIYNEFVLTTKNYIRTV--TDVKPEWL 691
              :|.|  .|..||.  .::..:..|||  |:.||.::
  Fly   741 --SCAD--TDRNIYQ--TISGHDPCRTVYFTNFKPAYM 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	193/708 (27%)
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	174/605 (29%)
		DEXHc_TDRD9	115..295	CDD:350746	60/184 (33%)
		TUDOR	892..1016	CDD:425754