Protein Alignment Dhx15 and dhx37

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_593520.1
• Gene: dhx37 / 2543371
• PomBaseID: SPAPB1A10.06C
• Length: 1183
• Species: Schizosaccharomyces pombe
• Alignment Length: 766
• Identity: 245/766 - (31%)
• Similarity: 391/766 - (51%)
• Gaps: 132/766 - (17%)

  Fly    48 PTMNPL----TNTPYS--QRYQNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIP 106
            ||.:.:    ..|.|:  .|...:.:.|:|||:...:...|..:..:..:::.|.||||||||:|
pombe   368 PTADDIEIKGRKTTYTIINRPPEIQESRLALPIVAEEQRIMEQIFANDVVIICGATGSGKTTQLP 432

  Fly   107 QWCVDFAVSKGRKG----VSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLLK 167
            |:..:...|.....    ::.||||||||:|:|:|||||: .....:|.|.|||:......|.:|
pombe   433 QFLFEAGFSSPESENPGMIAITQPRRVAAVSIAKRVSEEL-TGFSSKVSYQIRFDSTINPDTAIK 496

  Fly   168 YMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSD----------LKLV 222
            :||||:||||..||.:|..|..:::||||||::.||||:|:|..::|.|.:          |||:
pombe   497 FMTDGILLRELSSDFLLTAYSAVIVDEAHERSVNTDILLGLLSRIVRLRREMSKSDQKVKPLKLI 561

  Fly   223 VMSATLDAGKFQQ----YFDNAPLMKVPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEIEG 283
            :|||||....|.:    :....|::|:..|.:||.|.:....:.|||:.|...|..||. ....|
pombe   562 IMSATLRVTDFSENKLLFSVPPPIIKIDARQYPVSIHFNRTTKPDYLQDAFDKVCLIHK-RLPAG 625

  Fly   284 DILMFLTGQEEIEEACKRIKR------------------------EIDNLGSEIGELK------- 317
            .||:|||||:|:|:.|:.:::                        |.::|.||..::.
pombe   626 SILVFLTGQQEVEQLCQMLRKRFVRSFRPLKSRARIVVSRKTMSVENEDLQSETEDIDQVPTSSS 690

  Fly   318 -------------CIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFV 369
                         .:||||.|....|.::|:.:|..:      |..:|:||:||||:||..:.:|
pombe   691 SSVTYDDESEPMYVLPLYSLLTTEDQMKVFDSSPEGH------RMCIVATNVAETSITIPNIRYV 749

  Fly   370 IDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPE 434
            :|.|.||::|||.:..|:...|..||||:|.||:||||||.||.|:|||:...|.:....::.||
pombe   750 VDCGKAKERVYNEKTSVQKFEVRWISKANADQRAGRAGRTGPGHCYRLYSSAVFDSSFPLHSLPE 814

  Fly   435 ILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALDDDGNLTDLGAVMSEFP 499
            |||:.:.::|||:|.:.||::.:|.|...|....|.::|:||:.|.|:|.:|.||.||..||.||
pombe   815 ILRTPVESIVLQMKNMNIDNIANFPFPTSPGRSRLEKSLKLLSNLGAIDSEGVLTKLGEQMSLFP 879

  Fly   500 LDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFV--------------RPNEAKKAADE----- 545
            |.|:.:||||...||.|...::::.:.||:.|.||              |..|.....|:
pombe   880 LSPRFSKMLIIGQQHGCLPYVIALVSALSINQLFVSKQSLLYDAHDKNSRSEETDLIDDDEIKQK 944

  Fly   546 ------------AKMRFAHIDGD--HLTLLNVYHAFKQSSEDPNWCYENFINFRSLKSADNVRQQ 596
                        |..||..||.|  .|:||:...|:..:|:...:|.||::..::|:...|:|:|
pombe   945 EEYKNRMRGYFNAISRFQAIDPDAPALSLLSAVCAYDYASDKRKFCKENYLREKALEEVTNLRKQ 1009

  Fly   597 LARIMDRFNLRRTSTEFTSKDYY---------VNI---RKALVQGFFMQVA--HLERTGYY-LTI 646
            :..::.|:.:|      ..|:::         |.|   |:.:...:..|||  ..|:.||. |..
pombe  1010 IIGLLKRYMVR------VEKEFFKLQLKPPTSVQIKALRQFIASAYIDQVALYDKEKRGYVTLFP 1068

  Fly   647 KDNQNVQLHPSTCLDHKPDWVIYNEF--VLTTKNYIRTVTDVKPEWLCCLA 695
            ..::.||..|....:...::|:|...  ..:.:.|:..:|::.||.|..||
pombe  1069 SGSEVVQFVPDRTYNIDSEYVVYLSLHESRSGRVYMSPLTEISPEHLARLA 1119

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	236/731 (32%)
dhx37	NP_593520.1	PTZ00108	<69..314	CDD:240271
		HrpA	397..>909	CDD:441249	189/519 (36%)
		OB_NTP_bind	1041..1121	CDD:400182	20/79 (25%)