Protein Alignment Dhx15 and ddx-15

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_741147.1
• Gene: ddx-15 / 175771
• WormBaseID: WBGene00018967
• Length: 739
• Species: Caenorhabditis elegans
• Alignment Length: 734
• Identity: 515/734 - (70%)
• Similarity: 614/734 - (83%)
• Gaps: 18/734 - (2%)

  Fly     2 SKRRIEVGETYGSKAKKDPEASSSSAA------AAAGTVAQILGGFVPNKQPPTMNPLTNTPYSQ 60
            |:.|:::..:.....::.|...|.|.:      ::.....||  |.|.|.: ..:||..|.|:|.
 Worm     3 SRHRLDLDGSGRGDRRRSPNRRSRSRSRSPHRRSSPDRKRQI--GAVGNMK-IQINPYNNQPFSN 64

  Fly    61 RYQNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWCVDFAVSKGRKG----- 120
            ||..:::||..|||:||:..||.||..:|||.||||||||||||||||.|:| :.:.::|
 Worm    65 RYWAIWEKRSQLPVWEYKEKFMELLRNNQCITLVGETGSGKTTQIPQWAVEF-MKQQQQGQPPGQ 128

  Fly   121 ---VSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLLKYMTDGMLLREAMSDP 182
               |:|||||||||||||.||:|||||.||:|||||||||||.:.:|:|||.||||||||||:.|
 Worm   129 ARLVACTQPRRVAAMSVATRVAEEMDVVLGQEVGYSIRFEDCISERTVLKYCTDGMLLREAMNSP 193

  Fly   183 MLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQYFDNAPLMKVPG 247
            :||:|:|::||||||||||||||||::||::|.|:|:|:|:|||||||||||:||::.||:.|||
 Worm   194 LLDKYKVLILDEAHERTLATDILMGLIKEIVRNRADIKVVIMSATLDAGKFQRYFEDCPLLSVPG 258

  Fly   248 RTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEIEGDILMFLTGQEEIEEACKRIKREIDNLGSE 312
            ||.|||||:||..|:|||||||||||||||.||:|||||:|||||||||||||||.|||..||::
 Worm   259 RTFPVEIFFTPNAEKDYLEAAIRTVIQIHMVEEVEGDILLFLTGQEEIEEACKRIDREIQALGAD 323

  Fly   313 IGELKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQ 377
            .|.|.||||||||||..||||||||||...||||.||.|:||||||||||||||||||||||:||
 Worm   324 AGALSCIPLYSTLPPAAQQRIFEPAPPNRPNGAISRKCVISTNIAETSLTIDGVVFVIDPGFSKQ 388

  Fly   378 KVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGT 442
            ||||||||||||||.|||||||.||:||||||:||||||||||.|:.:||||.|||||||||||:
 Worm   389 KVYNPRIRVESLLVCPISKASAMQRAGRAGRTKPGKCFRLYTETAYGSEMQDQTYPEILRSNLGS 453

  Fly   443 VVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALDDDGNLTDLGAVMSEFPLDPQLAKM 507
            |||||||||.:||||||||||||||||||||||||||.|::|||.||:||::|:|||||||||||
 Worm   454 VVLQLKKLGTEDLVHFDFMDPPAPETLMRALELLNYLQAINDDGELTELGSLMAEFPLDPQLAKM 518

  Fly   508 LIASCQHNCSNEILSITAMLSVPQCFVRPNEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQSSE 572
            ||.|.:.||||||||||||||||||:|||||.:..|||||.|||||||||||||||||:|||:.|
 Worm   519 LITSTELNCSNEILSITAMLSVPQCWVRPNEMRTEADEAKARFAHIDGDHLTLLNVYHSFKQNQE 583

  Fly   573 DPNWCYENFINFRSLKSADNVRQQLARIMDRFNLRRTSTEFTSKDYYVNIRKALVQGFFMQVAHL 637
            ||.|||:||||:|::|:||.||.||:|:||::||||.||:|.|:|||:|||||||.|||||||||
 Worm   584 DPQWCYDNFINYRTMKTADTVRTQLSRVMDKYNLRRVSTDFKSRDYYLNIRKALVAGFFMQVAHL 648

  Fly   638 ERTGYYLTIKDNQNVQLHPSTCLDHKPDWVIYNEFVLTTKNYIRTVTDVKPEWLCCLAPQYYDLN 702
            ||:|:|:|:||||.|.|||||.|||||:|.:||||||||||:|||||||:||||..:|||||||:
 Worm   649 ERSGHYVTVKDNQLVNLHPSTVLDHKPEWALYNEFVLTTKNFIRTVTDVRPEWLLQIAPQYYDLD 713

  Fly   703 NFPQCEAKRQLELLQQRLE 721
            |||..:.||:|..:.|.|:
 Worm   714 NFPDGDTKRKLTTVMQTLQ 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	479/627 (76%)
ddx-15	NP_741147.1	HrpA	74..>707	CDD:441249	481/633 (76%)