Protein Alignment Dhx15 and rha-1

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_495890.2
• Gene: rha-1 / 174417
• WormBaseID: WBGene00004355
• Length: 1301
• Species: Caenorhabditis elegans
• Alignment Length: 801
• Identity: 209/801 - (26%)
• Similarity: 353/801 - (44%)
• Gaps: 157/801 - (19%)

  Fly     7 EVGETYGSKAKKDPEASSS---SAAAAAGTVAQILGGFVPNKQPPTMN------------PLTNT 56
            |:.||..:     |||.:|   ....|...|::|......:..||..|            ||...
 Worm   291 EINETSAT-----PEAPTSLLTDVKLAQFPVSEICSASNISWAPPLQNWNPWRASNIDEEPLAFM 350

  Fly    57 PYSQRYQNLYKK---------------RIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIP 106
            ...|..|.:.:|               |..|||.:|:.:.::.::.::..::.||||.||:||:.
 Worm   351 SMEQISQRIMEKEDFKRGEALDKITAQRGELPVAQYRENIVQTVAENRVTLIKGETGCGKSTQVA 415

  Fly   107 QWCVDFAVSKGRKGVS----CTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTL-- 165
            |:.:: :..:...|.|    .:||||::|:|:|:||:.|...::||..||::|| |.:|.:..
 Worm   416 QFLLE-SFLENSNGASFNAVVSQPRRISAISLAERVANERGEEVGETCGYNVRF-DSATPRPYGS 478

  Fly   166 LKYMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDA 230
            :.:.|.|:|||  |.:..|.....:::||.|||.:.||.::.||:|:|....||::|:||||:|.
 Worm   479 IMFCTVGVLLR--MMENGLRGISHVIIDEIHERDVDTDFVLIVLREMISTYRDLRVVLMSATIDT 541

  Fly   231 GKFQQYFDN------APLMKVPGRTHPVEIFY------------------------TPEP----- 260
            ..|..:|.:      .|::.:.|||.||:.||                        .|.|
 Worm   542 DLFTNFFSSIPDVGPTPVITMHGRTFPVQSFYLEDILHNLQHMPEEPDQKKRKKGGPPPPDDDEG 606

  Fly   261 -------------------------------ERDYLEAAIRTVIQIHMCEEIEGDILMFLTGQEE 294
                                           |:|.....|..::.......::|.:|:||.|..|
 Worm   607 DEEVDDKGRNMNILTDPSINESLKTAMSRISEKDIPFGVIEAILNDIASRGVDGAVLVFLPGWAE 671

  Fly   295 IEEACKRIKREIDNLGSEIGELKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAET 359
            |...|.|: .|....| :..:.:.:||:|.|....|:::|...|..       ||::||||||||
 Worm   672 IMTLCNRL-LEHQEFG-QANKYEILPLHSQLTSQEQRKVFNHYPGK-------RKIIVSTNIAET 727

  Fly   360 SLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFK 424
            |:|||.||:|||...||:::|.....:........||.:..||.|||||.|.|..|.|.::..|:
 Worm   728 SITIDDVVYVIDSCKAKERMYTSNNNMVHFATVWASKTNVIQRRGRAGRVRAGYAFHLCSKMRFE 792

  Fly   425 NEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHF--DFMDPPAPETLMRALELLNYLAALDDDGN 487
             .:.|:...|:||..|..:.|.:|.|.:..:..|  ..:.||..:.::.:..:|..:.|||.:..
 Worm   793 -ALDDHGTAEMLRIPLHQIALTIKLLRLGSVGEFLGKALQPPPYDMVVESEAVLQAMGALDRNLE 856

  Fly   488 LTDLGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFVRPNEAKKAADEAKMRFA- 551
            ||.||.:::..|::|.:||:||........:.:..:.:.:|.|..||...:........:.:||
 Worm   857 LTSLGKMLARMPIEPVIAKVLILGTALGAGSVMCDVASAMSFPTPFVPREKHHSRLSGTQRKFAG 921

  Fly   552 HIDGDHLTLLNVYHAFKQ------SSEDPNWCYENFINFRSLKSADNVRQQLARIMDRFNLRRTS 610
            :...||:.:::|...:::      |:.:..:|....::...||..|..|:||..::      |..
 Worm   922 NKFSDHVAIVSVIQGYREAVQMGASAAEREFCERYSLSNPVLKMTDGARRQLIDVL------RNQ 980

  Fly   611 TEFTSK---DYYVNI----------RKALVQGFFMQVAHLERTGYYLTIKD-----NQNVQLHPS 657
            ..|...   |..||:          |..||...:..||:.......|||:.     |:...|.|.
 Worm   981 CSFPEDILFDISVNVNGPDRELNLMRSLLVMALYPNVAYYVGKRKVLTIEQSSALINKYSMLVPM 1045

  Fly   658 TC---LDHKPDWVIYNEFVLT 675
            ..   :|.....:::.|.|.|
 Worm  1046 NNRQEMDFPSPLLVFTEKVRT 1066

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	190/707 (27%)
rha-1	NP_495890.2	DSRM_DHX9_rpt1	4..73	CDD:380683
		DSRM_DHX9_rpt2	169..244	CDD:380684
		DEAD-like_helicase_N	325..562	CDD:475120	71/240 (30%)
		HrpA	380..>897	CDD:441249	153/530 (29%)
		OB_NTP_bind	1005..1087	CDD:400182	15/62 (24%)