Protein Alignment Dhx15 and l(2)37Cb

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: XP_319843.5
• Gene: l(2)37Cb / 1280046
• VectorBaseID: AGAMI1_007561
• Length: 891
• Species: Anopheles gambiae
• Alignment Length: 703
• Identity: 347/703 - (49%)
• Similarity: 473/703 - (67%)
• Gaps: 39/703 - (5%)

  Fly    12 YGSKAKKDPEASSS-------------SAAAAAGTVAQILGGFVPNKQPPTMNPLTNTPYSQRYQ 63
            :|||..|:..|...             .|...|||           |:......||..  .::..
Mosquito   187 FGSKDAKERAAQQQEYELLLDEQIDFVEALQMAGT-----------KKKDDKPELTEA--QRKKM 238

  Fly    64 NLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWCVDFAVSKGRKGVSCTQPRR 128
            .:.:.:.:||::.::.|.:..:..|..:::.|||||||||||||:..:...:...|.:.||||||
Mosquito   239 TIEETQKSLPIYPFKEDLIAAIQAHNILIIEGETGSGKTTQIPQYLYEAGFTNEGKKIGCTQPRR 303

  Fly   129 VAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLLKYMTDGMLLREAMSDPMLDQYQVILLD 193
            |||||||.||:|||.||||.|||||||||||::.:|::||||||.|.||.:|:|.|..|.|:::|
Mosquito   304 VAAMSVAARVAEEMAVKLGNEVGYSIRFEDCTSERTVIKYMTDGTLHREFLSEPDLASYAVMIID 368

  Fly   194 EAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQYFDNAPLMKVPGRTHPVEIFYTP 258
            |||||||.||||.|::|::.|.|.||||::.||||||.||..:||.||:.::|||.:||:||||.
Mosquito   369 EAHERTLHTDILFGLVKDIARFRKDLKLLISSATLDAEKFSDFFDKAPIFRIPGRRYPVDIFYTK 433

  Fly   259 EPERDYLEAAIRTVIQIHMCEEIEGDILMFLTGQEEIEEACKRIKREIDNLGSEIGELKCIPLYS 323
            .||.||::|.:.:|:|||..:.: ||||:|||||||||...:.::..:..|||::.||..:|:|:
Mosquito   434 APEADYIDACVVSVLQIHATQPL-GDILVFLTGQEEIEACQEMLQDRVKRLGSKLKELLILPIYA 497

  Fly   324 TLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVES 388
            .||.::|.:||||. ||||     |||:::|||||||||||.:::|||||||||..:|.|..:|:
Mosquito   498 NLPSDMQAKIFEPT-PPNA-----RKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMET 556

  Fly   389 LLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGID 453
            |||.|||||||.||:|||||..|||||||||..|:.||::|||.|||.|.|||..||.||.|||.
Mosquito   557 LLVVPISKASANQRAGRAGRVAPGKCFRLYTAWAYNNELEDNTVPEIQRINLGNAVLMLKTLGIH 621

  Fly   454 DLVHFDFMDPPAPETLMRALELLNYLAALDDDGNLTDLGAVMSEFPLDPQLAKMLIASCQHNCSN 518
            ||:||||:|||..:||:.|||.|..|.||:..|.||.||..|:|||:||.:||||:||.::.||.
Mosquito   622 DLLHFDFLDPPPHQTLILALEQLYALGALNHHGELTKLGRRMAEFPVDPMMAKMLLASEKYKCSE 686

  Fly   519 EILSITAMLSV-PQCFVRPNEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQSSEDPNWCYENFI 582
            ||:||.||||| ...|.||.:....||.|:..|.|..||||:|:.||:.:.:|.....|||||||
Mosquito   687 EIVSIAAMLSVNGAIFYRPKDKIIHADTARKNFNHRHGDHLSLMQVYNQWVESDYSTQWCYENFI 751

  Fly   583 NFRSLKSADNVRQQLARIMDRFNLRRTSTEFTSKDYYVNIRKALVQGFFMQVAHLERTGYYLTIK 647
            .:||:|.|.:||:||..:|.|..:...|.|..:    .|:|||:..|:|..||.|.::|.|.|:|
Mosquito   752 QYRSMKRARDVREQLVGLMQRVEIEMVSGESDT----TNVRKAITAGYFYHVARLSKSGNYKTVK 812

  Fly   648 DNQNVQLHPSTCL-DHKPDWVIYNEFVLTTKNYIRTVTDVKPEWLCCLAPQYY 699
            .||:|.:||::.| :..|.|::|:|.|.|||.::|:|.:::.:||..:||.||
Mosquito   813 HNQDVMIHPNSALFEDLPRWLLYHELVFTTKEFMRSVIEIESKWLLEVAPHYY 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	329/621 (53%)
l(2)37Cb	XP_319843.5	None