Protein Alignment Dhx15 and mle

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: XP_316626.5
• Gene: mle / 1277182
• VectorBaseID: AGAMI1_002111
• Length: 1320
• Species: Anopheles gambiae
• Alignment Length: 804
• Identity: 207/804 - (25%)
• Similarity: 341/804 - (42%)
• Gaps: 206/804 - (25%)

  Fly    63 QNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWCVDFAVSKGRKGVSC---- 123
            |...:.|..||:...:...|..::.|..:::.|.||.||||||.|:.::..::.| :|..|
Mosquito   376 QKSMRTREKLPISAMRKPIMEAINEHPVVLIRGNTGCGKTTQIAQFILEDYINSG-QGAYCNVCV 439

  Fly   124 TQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAK--TLLKYMTDGMLLREAMSDPMLDQ 186
            |||||::|:||::|::.|....||..||||:||:......  ::| :.|.|:|||:.  :..|..
Mosquito   440 TQPRRISAISVSERIANERCENLGVTVGYSVRFDSVLPRPYGSIL-FCTIGVLLRKL--EGGLRG 501

  Fly   187 YQVILLDEAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQYFDNAPLMKVPGRTHP 251
            ...:::||.|||.:.:|.::.||::::....||::::||||:|...|.:||.:.|:::||||..|
Mosquito   502 VSHVIVDEIHERDVNSDFILVVLRDMVHTYPDLRVILMSATIDTSLFSRYFGDCPVLEVPGRAFP 566

  Fly   252 VE----------IFYTPEP----------------------------------------ERDY-- 264
            ||          :.:.|.|                                        |..|
Mosquito   567 VEQLFLEDCIELLKFRPSPPEGGAGRRKRGKDGEDDGGDGGGECDADMPECGNLNEVIDESKYSP 631

  Fly   265 -LEAAIRTVIQIHMCEEI-------------EGDILMFLTGQEEIEEACKRIK-REIDNLGSEIG 314
             .:.|:..:|:.....|:             .|.:|:||.|...|....:::: |:
Mosquito   632 QTKQAMAMMIEADTPFELITALVDYVDQQGRPGAVLVFLAGWNMIFALMRQLQPRQ--------- 687

  Fly   315 ELKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKV 379
            .|..:||:|.||...|:::|      |..|. .|||:::|||||||:|||.||:|||...|:.|:
Mosquito   688 NLVVLPLHSQLPREDQRKVF------NHYGQ-RRKVILATNIAETSITIDDVVYVIDTCKARMKL 745

  Fly   380 YNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGTVV 444
            :.....:.:......::.:.:||.|||||..||.||.|.:...|. ::::|..||:.|:.|..:.
Mosquito   746 FTSHNNMTNYATVWAARTNLEQRKGRAGRVSPGMCFTLCSRARFA-KLEENLTPEMFRTPLHELA 809

  Fly   445 LQLKKLGIDDLVHF--DFMDPPAPETLMRALELLNYLAALDDDGNLTDLGAVMSEFPLDPQLAKM 507
            |.:|.|.:..:..|  ..::||..:.::.|..||..:..||::..||..|.:::..|::|:|.||
Mosquito   810 LSIKLLRLGAIGKFLSKAIEPPPLDAVIEAEVLLKEMRCLDEEEQLTPFGRILARLPIEPRLGKM 874

  Fly   508 LIAS-----CQ----------------------------------HNCSNEILSITAMLSVPQCF 533
            ::.|     |.                                  ..||:.:..:||       |
Mosquito   875 MVLSTLFGLCDTLTTMAAYSGTFSEVFLLELGQRRLMNHQKALSGQTCSDYVAMLTA-------F 932

  Fly   534 VRPNEAKKAADEAKMRFAHIDGDHL-TLLNVYHAFKQSSEDPNWCYENF-------INFRSLKSA 590
            ...::.:...:||:|||....|..: ||.::..|.||..|  |.|...|       :.|.|....
Mosquito   933 EMWSKKRAIGEEAEMRFCDWKGLQMPTLRSIAEAKKQLIE--NLCLAGFPQDTMMPLRFDSENPD 995

  Fly   591 DNVRQQLARIMDRFNLRRTSTEFTSKDYYVNIRKALVQGFFMQVAHLERTGYYLTIKDNQNVQLH 655
            .::...:|                          .|..|.:..|.:.:.....||.:....:...
Mosquito   996 SDLEMAMA--------------------------LLCIGLYPNVCYHKEKRRVLTTESRAALMHK 1034

  Fly   656 PSTCLDHKPDWVIYNEFVLTTKNYIRT----------VTDV--------KPEWLCCLAPQYYD-- 700
            .|....:.|....|..||...|  |||          ||.:        |.||  |......|
Mosquito  1035 TSVNCSNAPTTFPYPFFVFGEK--IRTRAVSCKQMSMVTPIHLLLFGCKKVEW--CHGSVRIDNW 1095

  Fly   701 LN-NFPQCEAKRQLEL---LQQRL 720
            || |...|:|...|.|   ||:.|
Mosquito  1096 LNLNMDPCDAAMILALRPCLQELL 1119

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	192/759 (25%)
mle	XP_316626.5	None