Protein Alignment Dhx15 and Dhx57

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_001157231.1
• Gene: Dhx57 / 106794
• MGIID: 2147067
• Length: 1388
• Species: Mus musculus
• Alignment Length: 783
• Identity: 224/783 - (28%)
• Similarity: 378/783 - (48%)
• Gaps: 161/783 - (20%)

  Fly    59 SQRYQNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWCVDFAVSKGRKGVS- 122
            |:::..:.::|..||.:|.:...::|||.||.:|:.|.||.||||||||:.:|.:::...:.|:
Mouse   532 SRQFHAILQERQLLPAWEERETILKLLSKHQVVVISGMTGCGKTTQIPQFILDNSLNGPPERVAN 596

  Fly   123 --CTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTAKTLLKYMTDGMLLREAMSDPMLD 185
              ||||||::|:|||:||::|...::|..|||.||.|...::.|.|.|.|.|:|||....|..|.
Mouse   597 IICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDATLQ 661

  Fly   186 QYQVILLDEAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQYFDNAPLMKVPGRTH 250
            ....|::||.||||..:|.|:.|||:::.||:.|::::||||||||.|.:||...|::.:|||..
Mouse   662 GVTHIIVDEVHERTEESDFLLLVLKDIVMQRATLQVILMSATLDAGLFSKYFSYCPVITIPGRAF 726

  Fly   251 PVEIFY----------------------------------------------------------- 256
            ||:.|:
Mouse   727 PVDQFFLEDALAVTRYVLQDGSPYMRSMKQIAKEKLKARHNRTAQEEVEEDLRLSLHLQDEEESV 791

  Fly   257 ---TPEPERDYLEAAIR------TVIQIHMCEEIE-----------------------GDILMFL 289
               .|:.:.|:.:..||      :||:.....:.|                       |.:|:||
Mouse   792 KDTIPDQQLDFKQLLIRYKGVSKSVIKTMSVMDFEKVNLELIEALLEWIVDGKHAYPPGAVLVFL 856

  Fly   290 TGQEEIEEACKRIKREIDNLGSEIGELKCI--PLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVV 352
            .|..||:...:::  :.::|.:.....:|:  ||:|:|....||.:| ..||....     |:::
Mouse   857 PGLAEIKMLYEQL--QSNSLFNNRRSHRCVIHPLHSSLSSEEQQAVF-VKPPMGVT-----KIII 913

  Fly   353 STNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRL 417
            ||||||||:|||.||:|||.|..|:|.|:....:|||..:.:|:|:|.||.|||||...|.||.|
Mouse   914 STNIAETSITIDDVVYVIDSGKMKEKRYDAGKGMESLEDTFVSQANALQRKGRAGRVASGVCFHL 978

  Fly   418 YTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDL-----VHFDFMDPPAPETLMRALELLN 477
            :|...:.:::.....|||.|..|..:.|::|.|.:...     |....::||..::|..:...|.
Mouse   979 FTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSTHNLQSVFSRLIEPPHIDSLRASKVRLR 1043

  Fly   478 YLAALDDDGNLTDLGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFVRPNEAKKA 542
            .|.||..|..||.||..::..|:|.::.|:::......|.:..|:|.|.|:....||.|.:.|:.
Mouse  1044 DLGALTPDEKLTPLGYHLASLPVDVRIGKLMLLGSIFRCLDPALTIAASLAFKSPFVSPWDKKEE 1108

  Fly   543 ADEAKMRFAHIDGDHLTLLNVYHAFKQSSEDP-----NWCYENFINFRSLKSADNVRQQLARIMD 602
            |::.|:.||..:.|:|.||..|..::.|:::.     |:|.:||::.|:|:...::::|...::.
Mouse  1109 ANQKKLEFAFANSDYLALLCAYKGWQLSTKESARASYNYCRQNFLSGRTLQEMASLKRQFTELLS 1173

  Fly   603 -----RFNLRRTSTE-----------FTSKDYYVN-------------------IRKALVQGFFM 632
                 :..||....|           .|.::...|                   ::....:|.|.
Mouse  1174 DIGFVKEGLRAKEIEKRAQGGDGVLDATGEEANTNAENPKLISAVLCAALYPNVVQVKTPEGKFQ 1238

  Fly   633 Q----VAHLERTGYYL--TIKDNQNVQLHPSTC---LDH-KPDWVIYNEFVLTTKNYIR--TVTD 685
            :    |..|:.....|  ..|::..|.:|||:.   :.| ...:::|:|.:.|::.:||  ::..
Mouse  1239 KTSSGVVRLQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVS 1303

  Fly   686 VKP 688
            |.|
Mouse  1304 VYP 1306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	222/771 (29%)
Dhx57	NP_001157231.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..107
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..154
		UBA_DHX57	181..218	CDD:270502
		RWD_DHX57	243..425	CDD:467661
		zf_CCCH_4	305..323	CDD:465719
		HrpA	545..>1172	CDD:441249	199/634 (31%)
		DEVH box	669..672		2/2 (100%)
		OB_NTP_bind	1215..1312	CDD:400182	18/92 (20%)