DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhx15 and dhx16

DIOPT Version :9

Sequence 1:	NP_001260766.1	Gene:	Dhx15 / 35654	FlyBaseID:	FBgn0033160	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001116881.3	Gene:	dhx16 / 100127179	XenbaseID:	XB-GENE-480525	Length:	1033	Species:	Xenopus tropicalis

Alignment Length:	691	Identity:	354/691 - (51%)
Similarity:	476/691 - (68%)	Gaps:	34/691 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SAAAAAGTVAQILGGFVPNKQPPTMNPLTNTPYSQRYQNLYKKRIALPVFEYQADFMRLLSLHQC 90
            |:|...||:         :|:......|:.:  .::..::.:.|.:||||.|::|.::.:|.||.
Frog   356 SSAQMKGTI---------DKEEENSEVLSES--ERKKLSIQEVRRSLPVFPYRSDLLQAISDHQI 409

  Fly    91 IVLVGETGSGKTTQIPQWCVDFAVSKGRKGVSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIR 155
            :::.|||||||||||||:..:...:|....:.||||||||||||:.|||:||.||||.|||||||
Frog   410 LIIEGETGSGKTTQIPQYLHEHGYTKNGLKIGCTQPRRVAAMSVSARVSQEMGVKLGNEVGYSIR 474

  Fly   156 FEDCSTAKTLLKYMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSDLK 220
            ||||::.:|:||||||||||||.:::|.|..|.||::||||||||.||:|.|::|::.|.|.|||
Frog   475 FEDCTSERTVLKYMTDGMLLREFLTEPDLASYSVIIIDEAHERTLHTDVLFGLIKDIARFRQDLK 539

  Fly   221 LVVMSATLDAGKFQQYFDNAPLMKVPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEIEGDI 285
            ::|.||||:..:|..:||:||:.::|||.:||:|:||..||.|||||.:.:|:|||:.:. .|||
Frog   540 VLVASATLNTERFSSFFDDAPVFRIPGRRYPVDIYYTKAPEADYLEACVVSVLQIHVTQP-PGDI 603

  Fly   286 LMFLTGQEEIEEACKRIKREIDNLGSEIGELKCIPLYSTLPPNLQQRIFEPAPPPNANGAIGRKV 350
            |:|||||||||..|:.::.....|||:|.|:..:|:|:.||.::|.:||||.||    ||  |||
Frog   604 LVFLTGQEEIETCCEMLQERCRRLGSKIAEMLVLPIYANLPSDMQAKIFEPTPP----GA--RKV 662

  Fly   351 VVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCF 415
            |::||||||||||||:::||||||.|||.||.|..:|||:|:|.|||||.||:|||||...||||
Frog   663 VIATNIAETSLTIDGIIYVIDPGFCKQKSYNARSGMESLIVTPCSKASANQRAGRAGRVAAGKCF 727

  Fly   416 RLYTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLA 480
            ||||..|:||||:|.|.|||.|:|||.|||.||.|||:||:||||||||..|||:.|||.|..|.
Frog   728 RLYTAWAYKNEMEDTTVPEIQRTNLGNVVLLLKSLGINDLIHFDFMDPPPHETLVLALEQLYALG 792

  Fly   481 ALDDDGNLTDLGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQ-CFVRPNEAKKAAD 544
            ||:..|.||.||..|:|.|:||.|:|:::||.|:.||.:||:|.|||||.. .|.||.:....||
Frog   793 ALNHLGELTKLGRRMAELPVDPMLSKIILASEQYGCSEQILTIAAMLSVNNTIFYRPKDKLVHAD 857

  Fly   545 EAKMRFAHIDGDHLTLLNVYHAFKQSSEDPNWCYENFINFRSLKSADNVRQQLARIMDRFNLRRT 609
            .|:..|....|||:.|||||..:.:|.....|||||||..|||:.|.:||:||..:|.|..:..|
Frog   858 TARANFTVPGGDHMVLLNVYTQWVESGHSLQWCYENFIQARSLRRARDVREQLEGLMGRIEIELT 922

  Fly   610 STEFTSKDYYVNIRKALVQGFFMQVAHLERTGYYLTIKDNQNVQLHPSTCL-DHKPDWVIYNEFV 673
            |.|..|    :.:|||:..|:|...|.|.|:| |.|:|..|.|.:||::.| :.:|.||||:|.|
Frog   923 SCEGDS----IPVRKAITAGYFYHTARLTRSG-YKTVKQQQAVYIHPNSSLHEEQPRWVIYHELV 982

  Fly   674 LTTKNYIRTVTDVKPEWLCCLAPQYYDLNNFPQCEAKRQLE 714
            .|||.|:|.:.::...||..:||.||         ..|:||
Frog   983 FTTKEYMRQIIEIDSTWLLEVAPHYY---------KSRELE 1014

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_001260766.1	Motor_domain	50..>102	CDD:277568	17/51 (33%)
		DEXDc	67..255	CDD:214692	107/187 (57%)
		DEXDc	91..228	CDD:238005	85/136 (63%)
		HELICc	315..408	CDD:197757	57/92 (62%)
		HA2	478..561	CDD:214852	38/83 (46%)
		OB_NTP_bind	595..698	CDD:285018	41/103 (40%)
dhx16	NP_001116881.3	PTZ00121	<88..381	CDD:173412	6/35 (17%)
dhx16	NP_001116881.3	HrpA	356..1005	CDD:224557	347/671 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D113216at33208
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X141
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010