Protein Alignment Dhx15 and dhx35

DIOPT Version :10

• Sequence 1: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: XP_073795786.1
• Gene: dhx35 / 100037310
• ZFINID: ZDB-GENE-070410-11
• Length: 699
• Species: Danio rerio
• Alignment Length: 680
• Identity: 321/680 - (47%)
• Similarity: 453/680 - (66%)
• Gaps: 32/680 - (4%)

  Fly    49 TMNPLTNTPYSQRYQNLYKKRIALPVFEYQADFMRLLSLHQCIVLVGETGSGKTTQIPQWCVDFA 113
            |.:|:...|::.  ..:.|:|..||||:::.:.:.|:...|.:|:||||||||:|||||:.::..
Zfish    31 TGSPIVFNPHTA--LTIEKQRQRLPVFKHRNNILYLVESFQTVVIVGETGSGKSTQIPQYLLEAG 93

  Fly   114 VSKGRKGVSCTQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIRFEDCSTA-KTLLKYMTDGMLLRE 177
            .:...|.:..||||||||.|||.||:||....||.||||:|||:|||.. .|.:|::|||||:||
Zfish    94 WAAEGKVIGVTQPRRVAATSVATRVAEERGAFLGHEVGYTIRFDDCSDPHATRIKFLTDGMLVRE 158

  Fly   178 AMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSDLKLVVMSATLDAGKFQQYF----- 237
            .||||:|.:|.|::|||||||||.|||.:|:||:::::|.||:|:|.||||||.|||.:|
Zfish   159 MMSDPLLKKYSVLILDEAHERTLYTDIAIGLLKKILKKRRDLRLIVASATLDAKKFQDFFNLNES 223

  Fly   238 -----DNAPLMKVPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEIEGDILMFLTGQEEIEE 297
                 |...::.|.|||.||:||||..|..||::|.:.||::||..|: :||:|.|||||||:|:
Zfish   224 GDASKDTCGILTVEGRTFPVDIFYTVSPVPDYVKATVETVLKIHETED-DGDVLAFLTGQEEVEK 287

  Fly   298 ACKRIKREIDNLGSEIGELK--CI-PLYSTLPPNLQQRIFEPAPPPNANGAIGRKVVVSTNIAET 359
            ....::.:...| |..|..|  |: |:|:.||.|.|.|:||...|      ..|||||:||||||
Zfish   288 VVSLLQEQARTL-SRYGMKKHLCVLPMYAGLPYNEQMRVFERMAP------TVRKVVVATNIAET 345

  Fly   360 SLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRSGRAGRTRPGKCFRLYTEKAFK 424
            |:||:|||||||..|.|.:.||||..:|||:|:|||||||.||:|||||.|.|||||||||:.|:
Zfish   346 SITINGVVFVIDCAFVKIRAYNPRTAIESLIVTPISKASACQRAGRAGRNRAGKCFRLYTEEDFE 410

  Fly   425 NEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALDDDGNLT 489
             ::.::|.||:.||||..|:||||.||||:::.|.|:.||..:::::|||||..|..||..|.||
Zfish   411 -KLPESTVPEMQRSNLAPVILQLKALGIDNVLRFSFLSPPPAQSMVQALELLFALGGLDQYGRLT 474

  Fly   490 D-LGAVMSEFPLDPQLAKMLIASCQHNCSNEILSITAMLSVPQCFVRPNEAKKAADEAKMRFAHI 553
            | :|..|:||||.|..||||:.|....||.||::|.||:.:...||.|:..:|:|.....:||..
Zfish   475 DPMGVRMAEFPLSPMFAKMLLESGNFGCSKEIVTIAAMMQIQNIFVAPHNQRKSAAREHRKFAVA 539

  Fly   554 DGDHLTLLNVYHAFKQSSEDPNWCYENFINFRSLKSADNVRQQLARIMDRFNLRRTSTEFTSKDY 618
            :|||||:||||.||.:..:...||.::|:|::.|..|..||:||..::::|.:.|||:|   .|.
Zfish   540 EGDHLTMLNVYEAFIKHQKSSQWCQDHFLNYKGLLRATAVREQLRHLLNKFKVPRTSSE---GDP 601

  Fly   619 YVNIRKALVQGFFMQVAHLERTGYYLTIKDNQNVQLHPSTCL--DHKPDWVIYNEFVLTTKNYIR 681
            .| |.:.:|.|||...|.:..:|.|.|::|::.:.:||.:.|  :..|.||::||.|.|:|.|:|
Zfish   602 DV-ILRCIVSGFFANAARMHHSGSYRTLRDDRELYIHPDSVLYGEKPPKWVVFNEVVQTSKYYMR 665

  Fly   682 TVTDVKPEWLCCLAPQYYDLNNFPQCEAKR 711
            .||.|:..||..|||.:|.........:||
Zfish   666 DVTAVESSWLVELAPHFYKQAKHGSLSSKR 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	308/636 (48%)
dhx35	XP_073795786.1	None