Protein Alignment cos and sub

DIOPT Version :9

• Sequence 1: NP_001260765.1
• Gene: cos / 35653
• FlyBaseID: FBgn0000352
• Length: 1201
• Species: Drosophila melanogaster
• Sequence 2: NP_001286548.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Alignment Length: 690
• Identity: 139/690 - (20%)
• Similarity: 243/690 - (35%)
• Gaps: 237/690 - (34%)

  Fly    13 PHRELKDLL--------RSFGPTEPKKDAQAVDEGADS-KDSEAQVPAAEKDNPSISETDPNGNA 68
            |.||::..|        |.|.| .|.|..:..|...:| ::|.::....|.:....|.....|.:
  Fly    10 PRREVRSFLMARDPSIDRRFRP-RPNKKMRLFDNIQESEEESFSEYSDTESEYKYQSSEATEGAS 73

  Fly    69 EQDSAADSKTIPDANGNDSGQKDY------PDSAYCVQAIPISASALGLPSALPGGDPMDSIAAG 127
            ...|||||..:      ::|.:.:      .|::   :|..:|..|    :.|.....:||.:..
  Fly    74 CATSAADSSNV------ETGPQVFLRLRPVKDAS---KAYIVSEEA----NVLITSCKVDSTSNN 125

  Fly   128 LIQVGPHTVPVTHALPSSSSQEQVYHQTVFPLITLFLEGFDASVVTYGQRGQGKSYTLYGNVQDP 192
            :.::..| ...|....|:..|..:|...|.|.|   :|....:::|||..|.||:|||.|:
  Fly   126 VNRMEKH-FGFTSIFDSTVGQRDIYDTCVGPKI---MEEECVTIMTYGTSGSGKTYTLLGD---- 182

  Fly   193 TLTDSTEGVVQLCVRDIFS------------------------------------------HISL 215
               |...|::...:.:||:                                          .||.
  Fly   183 ---DVRAGIIPRALENIFTIYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISA 244

  Fly   216 HPER-------------------TYAINVGFVEICGGDVCDLL---------------------- 239
            |.:|                   :..:.|.||||....|.|||
  Fly   245 HHQRLKQVIDGDHMFETKASTDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGN 309

  Fly   240 -------GMGNIHCTNVDAVFHWLQVG----------LSARQSLPAHTLFTLTLEQQWVSKEGLL 287
                   |:.::..|:.:.....|::|          ::|..| .:|.:||:.:.:  .::.|:.
  Fly   310 KGHVFIKGLTSVFVTSSEEALRLLRLGQQRSTYASTSVNANSS-RSHCVFTVDILK--YNRSGIT 371

  Fly   288 QHRLSTASFSDLCGTERCGDQPP------------------GRPLDAGLCMLEQVISTLTDPGLM 334
            ..  |:..|.||.|:||..:...                  ||.|||...:.::..:.:
  Fly   372 TQ--SSYKFCDLAGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADI------ 428

  Fly   335 YGVNGNIPYGQTTLTTLLKDSFGGRAQTLVILCVSPLEEHLPETLGNLQFAFKVQCVRNFVIMNT 399
                  |||..:.||.||:.:..|:.:..:|:.|:||:::..|.|..|.||   ...:|.:.
  Fly   429 ------IPYRDSKLTMLLQAALLGKEKLAMIVTVTPLDKYYEENLNVLNFA---SIAKNIIF--- 481

  Fly   400 YSDDNTMIVQPAEPVPE---------------SNSSAGPLSQAGPGDNFGLQFAASQWSKLVTNA 449
                       .|||.:               |....|..::....:|..||....|    :...
  Fly   482 -----------KEPVIKQHRVSYCGFMEFSKMSTCEGGDYTKELEDENVRLQLEIEQ----LKYD 531

  Fly   450 EGLFSKLIDSKLITEVE--------------KEQIEEWLFLKQECEECLSSTEAMRQQKQLVPIL 500
            ..|..:|::.||..|:.              :::.|:.|.:.|...|.:.|::..|.::|:
  Fly   532 HVLQMQLLEEKLRRELTATYQEIIQNNKKQYEDECEKKLLIAQRESEFMLSSQRRRYEEQI---- 592

  Fly   501 EAEEPEDVNSEAANSESPNSDNE-NDTDNESHRP--DLDD 537
                 ||:..|....::|.||.: :|..|||..|  .|||
  Fly   593 -----EDLKDEIEELKNPASDTDISDDPNESKSPIEILDD 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cos	NP_001260765.1	Motor_domain	132..389	CDD:277568	75/374 (20%)
		SPEC	657..856	CDD:295325
sub	NP_001286548.1	KISc	89..477	CDD:276812	82/425 (19%)
		Kinesin	93..479	CDD:278646	82/423 (19%)
		GBP_C	<512..603	CDD:303769	19/103 (18%)
		coiled coil	576..586	CDD:293879	2/9 (22%)
		coiled coil	592..603	CDD:293879	3/19 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437842
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030