Protein Alignment cos and Klp64D

DIOPT Version :9

• Sequence 1: NP_001260765.1
• Gene: cos / 35653
• FlyBaseID: FBgn0000352
• Length: 1201
• Species: Drosophila melanogaster
• Sequence 2: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Alignment Length: 704
• Identity: 167/704 - (23%)
• Similarity: 286/704 - (40%)
• Gaps: 207/704 - (29%)

  Fly    81 DANGNDSGQKDYPDSAYCVQAI---------PISASALGLPSALPGGDPMDSIAAGLIQVGPHTV 136
            :||...:.|.|  |....|:.:         .:||.||...|       :|.|...:..:.|:..
  Fly     5 EANAGTTAQLD--DEIENVRVVVRTRPMDKNELSAGALSAIS-------VDKINRAITVMKPNAT 60

  Fly   137 ----PVTH----ALPSSSSQEQVYHQTVFPLITLFLEGFDASVVTYGQRGQGKSYTLYGNVQDPT 193
                |.|:    .....|:|..:|..|..|::...|||::.:::.|||.|.||:||:.||...|
  Fly    61 ANEPPKTYYFDNVFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSP- 124

  Fly   194 LTDSTEGVVQLCVRDIFSHISLHPE-RTYAINVGFVEICGGDVCDLLG--MGN------------ 243
               .|:|::......||.||:...| :.:.:.|.::||...:|.||||  :|.
  Fly   125 ---QTKGIIPNAFAHIFGHIAKAKENQKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIGV 186

  Fly   244 ---------IHCTNVDAVFHWLQVGLSAR---------QSLPAHTLFTLTLEQQWVSKEGLLQH- 289
                     :|  |.|.:.:.:::|...|         :|..:|.:|::|:|:..:. ||.:||
  Fly   187 FVKDLSGYVVH--NADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELG-EGDVQHV 248

  Fly   290 RLSTASFSDLCGTER-CGDQPPGRPL------DAGLCMLEQVISTLTDPGLMYGVNGNIPYGQTT 347
            |:......||.|:|| ...|..|:.|      :..|.:|..|||.|.|     |.:.:|||..:.
  Fly   249 RMGKLQLVDLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVD-----GKSTHIPYRNSK 308

  Fly   348 LTTLLKDSFGGRAQTLVILCVSPLEEHLPETLGNLQFAFKVQCVRNFVIMNTYSDDNTMIVQPAE 412
            ||.||:||.||.::|::...:||.:.:..||:..|::|.:.:.::|.:.:|....|
  Fly   309 LTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKD--------- 364

  Fly   413 PVPESNSSAGPLSQAGPGDNFGLQFAASQWSKLVTNAEGLFSKLIDSKLITEVEKEQIEEWLFLK 477
                                                                          .|.
  Fly   365 --------------------------------------------------------------ALL 367

  Fly   478 QECEECLSSTEAMRQQKQLVPILEAEEPEDVNSEAANSESPNSDNENDT-DNESHRP---DLDDK 538
            :..:|     |..|.:|||      ||     .::...|.|:|:.|.|| |:|...|   :|:..
  Fly   368 RHFQE-----EIARLRKQL------EE-----GDSLEEEPPSSEEEEDTADDELEAPLEIELESS 416

  Fly   539 ----IESLMEEFRDKTDALILEKHAEYLSKHPKAVMQSQDREIE-AQPPEENGDDRKVSIGSRRR 598
                :|...::.|:||||   ||  |.|:|.    .....:||| |:..:|...::.||:  ..:
  Fly   417 TIQAVEKKPKKKREKTDA---EK--EELAKR----KNEHQKEIEHAKTEQETLRNKLVSL--EGK 470

  Fly   599 SVQPGASL----STAELAMLNRVASQQPPPPIDPESVVDPLESSSGEGI----RQAAL--AAAAA 653
            .:..|.:|    .|.||.:...:|..:.....: |::...|:..:.|.|    |.:.|  |:...
  Fly   471 ILVGGENLLEKAQTQELLLEQSIAELEQHEKSE-EALKQTLQQKATERIDIEERYSTLQDASTGI 534

  Fly   654 TAPIEQLQKKLRKLVAEIEGKQRQLREIEETIQVKQNI--------IAELVKNS 699
            |..|.::.:.|..:.:|:..:|::.:..:|.|.  :||        :.|||.||
  Fly   535 TKKIHRVMQMLMGVKSELADQQQEHQREKEGIY--ENIRSLSRELALCELVLNS 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cos	NP_001260765.1	Motor_domain	132..389	CDD:277568	87/305 (29%)
		SPEC	657..856	CDD:295325	13/51 (25%)
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	95/351 (27%)
		Kinesin	26..352	CDD:278646	94/344 (27%)
		RILP-like	<437..556	CDD:304877	27/125 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437767
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030