Protein Alignment cos and CG14535

DIOPT Version :9

• Sequence 1: NP_001260765.1
• Gene: cos / 35653
• FlyBaseID: FBgn0000352
• Length: 1201
• Species: Drosophila melanogaster
• Sequence 2: NP_001285726.1
• Gene: CG14535 / 34073
• FlyBaseID: FBgn0031955
• Length: 1131
• Species: Drosophila melanogaster
• Alignment Length: 1258
• Identity: 218/1258 - (17%)
• Similarity: 377/1258 - (29%)
• Gaps: 439/1258 - (34%)

  Fly    24 FGPTEPKKDAQAVDEGADSKDSEAQVPAAEKDNPSISETDPNGNAEQDSAADSKTIPDANGNDSG 88
            :|..:.|...:..|...:|..:|....|.:|....::.|||........||..:.
  Fly    40 YGVGKVKVMLRVADRDRNSGGTEPDFMALDKKKRQVTLTDPRTACPPPQAAQERA---------- 94

  Fly    89 QKDYPDSAYCVQAIPISASALGLPSALPGGDPMDSIAAGLIQVGPHTVPVTHALPSSSSQEQVYH 153
                                           ||  :||      |......:.......|..|..
  Fly    95 -------------------------------PM--VAA------PKMFAFDNLFTGEDKQSDVCA 120

  Fly   154 QTVFPLITLFLEGFDASVVTYGQRGQGKSYTLYGNVQDPTLTDSTEGVVQLC--------VRDIF 210
            ..:..:|...|||.|..::..|....|::.|:.|.:...:.:.|..|....|        :..::
  Fly   121 SALSEVIPAVLEGSDGCLLAMGYPATGQAQTVLGELGGGSGSGSASGSGVACSLGAAPCAIAWLY 185

  Fly   211 SHISLHPERT---YAINVGFVEICG--GDVC--DLL---------------------GMGNIHCT 247
            ..|....:::   :::.|..|.:..  .|..  |||                     |...:...
  Fly   186 KGIQERRQKSGARFSVRVSAVGVSATKPDALSQDLLISHAAESDDSPGIYLRDDFLGGPTELRAP 250

  Fly   248 NVDAVFHWLQVGLSAR---------------QSLPAHTLFTLTLEQQWVSKEGLLQHRLSTASFS 297
            ..:....:|...|:.|               ..|.:..:|||.:.|..:|::|.:....|.....
  Fly   251 TAERAALFLDSALAGRLKSSGSTASGSSGCAAPLESALIFTLHVYQYSLSRKGGVAGGRSRLHII 315

  Fly   298 DLCGTERCGDQPPGRPLDAGLCMLEQVISTLTDPGLMYGVNGNIPYGQTTLTTLLKDSFGGRAQT 362
            ||.|   |.::..|.||.....:|..::|....|          |:....||.||||
  Fly   316 DLGG---CANRNGGLPLSGIGNILLAILSGQRHP----------PHKDHPLTPLLKD-------- 359

  Fly   363 LVILCVSPLEEHL-------PE-----TLGNLQFAFKVQCVRNFVIMNTYSDDNTMIVQPAEPVP 415
                |::|:..|:       ||     .|..:|.|.::..:|.    ..:.....:.|..|:.:.
  Fly   360 ----CLAPITCHVAIVAHVRPEQSYQDALSTIQIASRIHRLRR----RKHRVPMPLAVGLAQGLG 416

  Fly   416 ESNSSAGPLSQAGPGDNFGLQFAASQWSKLVTNAEGLFSKLIDSKLITEVEKEQIEEWLFLKQEC 480
            .:.||||  |.|.|..:   :.:|.....:..|.:.           |:.|...:
  Fly   417 GNGSSAG--SGADPSSS---EISADTVIYMGPNDDA-----------TDGEHPPV---------- 455

  Fly   481 EECLSSTEAMRQQKQLVPILEAEEPEDVNSEA---ANSESPNSDNENDTDNESHRPDLDDKIESL 542
                           .:|.|.|.:...|.|:|   :..|.|.|      .:.|:.|.:..|
  Fly   456 ---------------YLPSLTAGDNRGVMSKALKGSGLEKPPS------KSASNSPMMMKK---- 495

  Fly   543 MEEFRDKTDALILEKHAEYLSKHPKAVMQSQDREIEAQPPEENGDDRKVSIGSRRRSVQPGASLS 607
                     |:..||..:....|                           .||.:|....||..|
  Fly   496 ---------AMAAEKAKKLPGSH---------------------------TGSLKRQAGAGACSS 524

  Fly   608 TAELAMLNRVASQQP-------PPPIDPESVVDP---LESSSGEGIRQAALAAAAATAPIEQLQK 662
            .       .:..:||       |.|| |..:|..   :.|..|..:|:|...||     :|||:.
  Fly   525 P-------MIPHEQPQIQAMGSPIPI-PRHMVSKGSMVPSPKGSPMRRAHPGAA-----LEQLEA 576

  Fly   663 KLRKLVAE--IEGKQRQLREIEETIQVKQNIIAELVKNSDTRSHAKQRFHKKRAKLEAECDKAKK 725
            .:||:..|  |:|.:....::.|...:.:.:           :|.||            |
  Fly   577 GMRKITEEQWIDGPRVSRAKVAEARHLMREV-----------NHVKQ------------C----- 613

  Fly   726 QLGKALVQGRDQSEIERWTTIIGHLERRLEDLSSMKHIAGESGQKVKKLQ----QSVGESRKQAD 786
                           |.|                   :.|...|..:.|.    .:.|.|:.|..
  Fly   614 ---------------ETW-------------------VDGPKSQSCRSLTACNLPAAGGSQTQGY 644

  Fly   787 DLQKKLRKECKLRCQMEAELAKLRESRETGKELVKAQGSPEQQGRQLKAVQARITHLNHILREKS 851
            ... ...|:..:|..:|.:..::.:|      .|.|..||       .|:..:::.    |::||
  Fly   645 GFM-DAHKKTMIRQWVENQTTQVFQS------TVSASNSP-------TALHWKLSQ----LKQKS 691

  Fly   852 DNLEEQP---------------------------GPEQQETLRHEI-------RNLRGTRDLLLE 882
            .:|.::|                           |.|.:::...|:       .:..|:||:
  Fly   692 LDLPDRPAFNPEPSLDLNQPCFESLPLLDPAPPDGDEDEDSGPSEVPPALPLLDDPLGSRDI--- 753

  Fly   883 ERCHLDRKLKRDKVLTQKEERKLLEC------DEAIEAIDAAIEFKNEMITGHRSIDTSDRIQRE 941
            .:.:|.|.|.|.....|..|.:|:..      ..:..:||..::...|.|        :..:.|:
  Fly   754 SQDNLHRMLSRHVSREQLHEAELVASRASSSHHPSQRSIDCGLQVTEEEI--------ARTMSRD 810

  Fly   942 KGEQMLMARLNRLSTEEMRTLLYKYFTKVIDLRDSSRKLELQLVQLERERDAWEWKERVLSNAVR 1006
            :........|:.||..:..:.:..:........:...:...|..||.|..:.:         ..:
  Fly   811 RDHDPSAHPLSALSHCDNISFVSSFNMACESFSECGERARQQFDQLARLHEIF---------TSQ 866

  Fly  1007 QARLEGERNAVLLQRQHEMKLTLMLRH--MAEETSASSASYGERALAPACVAPPVQASSDFDYDH 1069
            .|..|...:|.|.:.......:..:.|  :.:.:..|..:|   .|.|   :||.|.|      |
  Fly   867 LAMAEVTPSAALFRTDIGSVFSEPVYHFNVGQSSVCSEPAY---RLTP---SPPKQPS------H 919

  Fly  1070 FYKGGGNPS------------KALIKAPKPMPTGSALDKYKDKEQRSGRNIFAKFH----VLTRY 1118
            ....|..||            .||::.|         |...|...:.|...|...|    .|...
  Fly   920 SPSQGSLPSLNGIMEIAGMDDYALLRQP---------DGASDPNLQKGEKRFTPQHDDICELDEK 975

  Fly  1119 ASAAAAGSSGSTAEESTALIEST 1141
            :.|||.|...|..:....|.|.|
  Fly   976 SMAAAVGKGNSLEDAQHKLNEIT 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cos	NP_001260765.1	Motor_domain	132..389	CDD:277568	59/319 (18%)
		SPEC	657..856	CDD:295325	34/204 (17%)
CG14535	NP_001285726.1	Motor_domain	44..394	CDD:277568	74/423 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100