Protein Alignment cos and nod

DIOPT Version :9

• Sequence 1: NP_001260765.1
• Gene: cos / 35653
• FlyBaseID: FBgn0000352
• Length: 1201
• Species: Drosophila melanogaster
• Sequence 2: NP_001285129.1
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Alignment Length: 651
• Identity: 140/651 - (21%)
• Similarity: 229/651 - (35%)
• Gaps: 194/651 - (29%)

  Fly   140 HALPSSSSQEQVYHQTVFPLITLFLEGFDASVVTYGQRGQGKSYTLYGNVQDPTLTDSTEGVVQL 204
            ||.|::.||:::|...:.||:...||||..:.:.|||.|.||||:: |......:.....|::..
  Fly    52 HAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSM-GMTPPGEILPEHLGILPR 115

  Fly   205 CVRDIFSHISLHPERTY-AINV--GFVEICGGDVCDLLGMGNIHCTNVDA--------------- 251
            .:.|||..::...|... ||.|  .|:||......|||| ...|...|.|
  Fly   116 ALGDIFERVTARQENNKDAIQVYASFIEIYNEKPFDLLG-STPHMPMVAARCQRCTCLPLHSQAD 179

  Fly   252 VFHWLQVGLSARQSLP---------AHTLFTLTLEQQWVSKEGLLQHRLSTASFSDLCGTE---R 304
            :.|.|::|...|:..|         :|.:.|:.::.:        .|. |..:..||.|:|   |
  Fly   180 LHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVKSK--------THH-SRMNIVDLAGSEGVRR 235

  Fly   305 CGDQPPGRP----LDAGLCMLEQVISTLTDPGLMYGVNGNIPYGQTTLTTLLKDSFGGRAQTLVI 365
            .|.:...|.    ::.||..:.:|:.:      |...:..|||..:.|||:|:.|...::....:
  Fly   236 TGHEGVARQEGVNINLGLLSINKVVMS------MAAGHTVIPYRDSVLTTVLQASLTAQSYLTFL 294

  Fly   366 LCVSPLEEHLPETLGNLQF---------------------------AFKVQCVRNFVIMNTYSDD 403
            .|:||.:..|.|||..|:|                           .|:.....:..|.:..::.
  Fly   295 ACISPHQCDLSETLSTLRFGTSAKKLRLNPMQVARQKQSLAARTTHVFRQALCTSTAIKSNAANH 359

  Fly   404 NTMIVQPAEPVPESN-SSAGPLSQAGPGDNFGLQFAASQWSKLVTNAEGLFSKLIDSKLITEVEK 467
            |:::      ||:|. |:..|||..       |....|:..                  :|...|
  Fly   360 NSIV------VPKSKYSTTKPLSAV-------LHRTRSELG------------------MTPKAK 393

  Fly   468 EQIEEWLFLKQECEECLSSTEAM-------------RQQKQLVPILEAEEPEDVNSEAANSESPN 519
            ::..|.|.|::...| |||....             .:.:.|:|....:||...:|:  ||....
  Fly   394 KRARELLELEETTLE-LSSIHIQDSSLSLLGFHSDSDKDRHLMPPPTGQEPRQASSQ--NSTLMG 455

  Fly   520 SDNENDTDNESHRPDLDDKIESLM-----------EEFRDKTDALILEKHAEYLSKHPKAVMQSQ 573
            ...|.:       |....|::..|           :.|......:.|...:   |:...:.:|..
  Fly   456 IVEETE-------PKESSKVQQSMVAPTVPTTVRCQLFNTTISPISLRASS---SQRELSGIQPM 510

  Fly   574 DREIEAQPPEENGDDRKVSIGSRRRSVQPGASLSTAELAMLNRVASQQPPPPIDPESVVDPLESS 638
            :..:.|. |::....|.|.:.|..||...||......|....|:|
  Fly   511 EETVVAS-PQQPCLRRSVRLASSMRSQNYGAIPKVMNLRRSTRLA-------------------- 554

  Fly   639 SGEGIRQAALAAAA--ATAPIEQL----QKKLRKLVAEI-----------------EGKQRQLRE 680
               |||:.|.:...  .|..|..|    |||..:.|...                 .|..:||:|
  Fly   555 ---GIREHATSVVVKNETDAIPHLRSTVQKKRTRNVKPAPKAWMANNTKCFLDLLNNGNVKQLQE 616

  Fly   681 I 681
            |
  Fly   617 I 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cos	NP_001260765.1	Motor_domain	132..389	CDD:277568	77/309 (25%)
		SPEC	657..856	CDD:295325	11/46 (24%)
nod	NP_001285129.1	KISc	8..325	CDD:214526	76/289 (26%)
		KISc	8..318	CDD:276812	76/282 (27%)
		ComEA	540..648	CDD:224472	20/101 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437863
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030