DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam1 and igsf9ba

DIOPT Version :9

Sequence 1:NP_001246162.1 Gene:Dscam1 / 35652 FlyBaseID:FBgn0033159 Length:2038 Species:Drosophila melanogaster
Sequence 2:XP_009289969.2 Gene:igsf9ba / 567389 ZFINID:ZDB-GENE-060503-729 Length:1475 Species:Danio rerio


Alignment Length:1834 Identity:375/1834 - (20%)
Similarity:587/1834 - (32%) Gaps:592/1834 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   334 GESVETVLTVTAPLSAKIDP-PTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIE 397
            ||||.....|:.||:.:..| ..:...||.|..|...:...| ..|.....|:|..|.:..|:||
Zfish    38 GESVVLGCDVSHPLNGQQTPYVVEWFKFGVPIPFFINFRFYP-PHVDPEYAGRASLHGKASLQIE 101

  Fly   398 SVKKEDKGMYQCFVRNDQESAEASAELKLGGRFD--------------PPVIRQAFQE--ETMEP 446
            .|:.||:|.|:|.|            |.|..::|              ||.......:  |..| 
Zfish   102 QVRSEDQGWYECRV------------LMLEQQYDTFHNGSWVHLTVNAPPTFSDTPPQYVEARE- 153

  Fly   447 GPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCI 511
            |.|:.|.|.|.|||.|.::|..:|.::.:..:|.|..         ..|.:.::...|.|.|.|.
Zfish   154 GGSITLTCTAFGNPKPVVTWLREGDQLTSTRKYTVSD---------GSLTVQAITREDRGAYSCR 209

  Fly   512 AKSKVGVAEHSAKLNVYGLPYI-RQMEKKAIVAGETLIVTCPVAGYPID---SIVWERDNRAL-- 570
            |.|..|.|.|:.:|.|.|.||| ...|...:...:....||....||.:   :..||.||...  
Zfish   210 AHSDQGEALHTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWEEDNVYFKN 274

  Fly   571 PINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGS--LEVQ----VMVLPQI--VPF 627
            .:..:.::|.:|||||..| :..|...|||...|..|.|...|  |.||    |:.:|.:  ||.
Zfish   275 DLKLRVRIFIDGTLIIYRV-KPEDAGKYTCSPSNSLGISPSASAYLTVQYPARVVNMPPVIYVPR 338

  Fly   628 AYEDLINMGDSIDLFCQIQKGDRPIKVHWSFERSAGDYGFDQVQPQMRTNRISEKTSM----ISI 688
            ....:|.        |.:........|.|..:      |:     .:|..:....:.|    |.:
Zfish   339 KLSGIIR--------CPVDANPPVTSVRWEKD------GY-----PLRIEKYPGWSQMTDGSIRV 384

  Fly   689 PSASPAHTGRDTCIASNKAGTTTYS--VDLTVNVPPRWILEPTDKAFAQ--GSDAKVECKADGFP 749
            ...:....|..||:..|..||...|  ..|.:..||.:.:.|..: :.|  |.:..:.|.|.|.|
Zfish   385 AEVTEDSLGTYTCVPYNVLGTMGQSPPATLVLKDPPYFNVRPGGE-YRQEAGRELVIPCAASGDP 448

  Fly   750 K-PQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSA---- 809
            : |.:.|:| ||      |..:...|: :..|:|...::.|.:.|.:.|.|.|.:.|..::    
Zfish   449 EIPTIQWRK-VG------KPSRSKHNL-LPSGSLQFVSLSKEDHGEWECVATNVVTSITASTRLF 505

  Fly   810 VIMISVQAPPEFTEKLRNQTAR-RGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEI 873
            ||..|..||..........:|. ..||..   :...|:...:.:.    .:..|||   ....:.
Zfish   506 VIGTSPHAPTNVHVSASTSSANVSWEPGY---DGGFEQTFSVWYG----PVKVKND---VGTHDW 560

  Fly   874 LSTGVMSS---LSIKRTERSDSALFTCVATNAFGSDDASINMIVQ------EVPE-----MPYAL 924
            ||..|..|   |.::..|...:..|:.:|.|..|:...|..:.|.      ..||     .|...
Zfish   561 LSIPVPGSQMWLVVQGLEPKTAYQFSVLAQNKLGTGPFSEVVTVTTGGYPISTPEPLVLLTPPRC 625

  Fly   925 KVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYN 989
            ...:::.:.|.|:|..|.:..||:|||:||| |....|..:|. ::|...||...:.|...:.|.
Zfish   626 LTANRTQQGVLLTWLPPANHTSPIDRYVIEF-RLGEKWEVLDD-LIPATETEIIARDLIQDSWYE 688

  Fly   990 IRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYV 1054
            .|.:|......|:||..|.:.:.:                         |.|.||.:.|.|...|
Zfish   689 FRALAIMDDLVSESSNVVGVSSTD-------------------------PFPPTEISDEGLAKPV 728

  Fly  1055 GYKLSNT----NSSYVFETIN--FITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEK 1113
            ...:..|    .::.:|.|:.  |:   .|:|..:|:..|                         
Zfish   729 VAGIVATICFLAAAILFSTLAACFV---NKQHRRKLKRKR------------------------- 765

  Fly  1114 QFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKT 1178
                     .||.....|..:.::      .|||....| |:.|         |.:..:..|:..
Zfish   766 ---------DPPLSITHTRKSIES------PPPLTPLPG-IEPY---------WEEPDRSSYRPP 805

  Fly  1179 ASSDTVLHGLKKYTNYTMQVLAT-------TAGGDG--VRSVPIHCQTEPDVPEAPTDVKALVMG 1234
            ::|..:..|     ..:.:.:|:       :.||.|  |:.:|           :|...|.|   
Zfish   806 STSPQLSSG-----KISPESIASSRPPSLASVGGHGLYVKKLP-----------SPRKEKEL--- 851

  Fly  1235 NAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTAST 1299
                                 ::|.|.:.|.|..|.....|        |.|...|.|.      
Zfish   852 ---------------------SLYKKTKRAITSKKYSVSKH--------EAEVTTPIEL------ 881

  Fly  1300 TIGEGQQSKSIV---AMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFS 1361
             |..|...:.::   .:.|...|.:|..|      .|.|::.:        .||.....:     
Zfish   882 -ISRGPDGRFVMDPNDIDSSLKPRRIEGF------PFVEESDL--------YPEFRQSDE----- 926

  Fly  1362 ANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALT 1426
            .||....||.    :.:..|......|...|:            .:.||.               
Zfish   927 ENDDPGPLPP----VMATLRPQISPVSSSQES------------YMQPPA--------------- 960

  Fly  1427 VKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLC--GSRYQVYATG------- 1482
                               |.|.|             :..:||:..  |||.|  |||       
Zfish   961 -------------------YSPRF-------------QRPMEGMSISEGSRLQ--ATGQSRVSHF 991

  Fly  1483 ---------FNNIGAGEASDILNTRTKGQKP-KLPE-KPRFIEVSSNSVSLHFKAWKDGGCPMSH 1536
                     :..||:|...::       ..| .:|: .||...:||:      .::...| |..|
Zfish   992 HRVFPPGPFYGYIGSGAEVEL-------HPPFYMPDVSPRSSAMSSS------PSYPPEG-PFRH 1042

  Fly  1537 FVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGT 1601
            ..:..::.:                             |||..:.::|..:              
Zfish  1043 PTIPEEREE-----------------------------LRIHQYGASGHAL-------------- 1064

  Fly  1602 IAPLDDGSGHGNVH-------TRIRLPAWMPEWLDLNFMVPLIATVVVVAVGICVVCVALSRRRA 1659
              ||        ||       |.|    |.|.  |..|:                          
Zfish  1065 --PL--------VHSPPSSRSTEI----WQPP--DFPFL-------------------------- 1087

  Fly  1660 DDMRGGQKDVYYDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSN--YNTCDRIKR 1722
                 ||:            ||...|..|..      .|:.....:.||.|..:  .:|..::..
Zfish  1088 -----GQE------------GPRLALPPRHS------SYLHRDLPEPPPYPSHSRTVSTTSQLPS 1129

  Fly  1723 GRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHP--GMEDEICPY---- 1781
            ....|:.........|:|..:     ||......|............||.  ||...:.||    
Zfish  1130 SSAFLQLEAPRTHLSRSPGRF-----PPQGPSAKHITMQQAQTLGQLRHTAHGMGVPVLPYSGAT 1189

  Fly  1782 ------ATFHLL---GFREE----MDPTKA----MNFQTFPHQNGHAGPV-----PGHAGT---- 1820
                  :|.|..   |:|.|    |.|..|    :..|....|.....|:     ..|||:    
Zfish  1190 TRMGSPSTLHSESSDGWRSEAQPWMSPRAARKMDLGLQQVVLQPSRLSPLTQTPPSSHAGSPDIL 1254

  Fly  1821 MLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQ 1885
            :.||..|..:.| |.||.||.:.|:....|...:|...:||..                   .:|
Zfish  1255 VRPPPRPSILRS-SRSQEMPESARHPASVSFSRRSLSSSPATS-------------------PTQ 1299

  Fly  1886 GGSLYSGPGPEYDDPANC--APEEDQYGSQYGGPYGQPYDHYGSRGSMGR---RSIGSARNPGN- 1944
            |   .||..|.....|:.  |.....|.||...|..:..|.:|...|..|   ..:.|..:||. 
Zfish  1300 G---QSGQRPSLSYRAHMAFATAAASYPSQSPSPPAESSDAFGQMPSQRRTDEEMLPSEPSPGEH 1361

  Fly  1945 -GSPEPPPPPPRNHDMSNSSFNDSKESN----------EISEAECDRDHGPRGNYGAVKR----S 1994
             |:...|........:.|...|.:|:|:          :.::....:...|..:..:|:|    |
Zfish  1362 LGAVRVPAGSESFEALINYCINKAKKSSANKNNNSRFKKRTDMSTSQTQQPHASQASVQREHLSS 1426

  Fly  1995 PQPKDQRTTEEMRK 2008
            |..|..::|  :||
Zfish  1427 PSKKKWKST--LRK 1438

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam1NP_001246162.1 Ig 38..130 CDD:299845
IG 57..133 CDD:214652
IG_like 267..343 CDD:214653 4/8 (50%)
Ig 269..340 CDD:143165 4/5 (80%)
IG_like 353..425 CDD:214653 20/72 (28%)
IGc2 361..413 CDD:197706 18/51 (35%)
I-set 433..527 CDD:254352 27/95 (28%)
IGc2 446..517 CDD:197706 20/70 (29%)
I-set 533..618 CDD:254352 28/96 (29%)
IGc2 544..607 CDD:197706 20/67 (30%)
Ig 641..714 CDD:143165 14/78 (18%)
IGc2 735..804 CDD:197706 20/71 (28%)
I-set 819..914 CDD:254352 18/98 (18%)
Ig 833..921 CDD:299845 20/101 (20%)
FN3 918..1011 CDD:238020 29/97 (30%)
FN3 1018..1116 CDD:238020 15/103 (15%)
FN3 1124..1217 CDD:238020 19/101 (19%)
FN3 1222..1312 CDD:238020 15/92 (16%)
Ig 1339..1406 CDD:299845 9/66 (14%)
FN3 1409..1499 CDD:238020 17/107 (16%)
FN3 1504..1584 CDD:238020 12/81 (15%)
Dscam_C 1890..2008 CDD:289151 29/138 (21%)
igsf9baXP_009289969.2 IG 30..115 CDD:214652 26/77 (34%)
I-set 139..225 CDD:254352 27/95 (28%)
I-set 229..321 CDD:333254 28/92 (30%)
Ig 345..415 CDD:325142 14/88 (16%)
Ig 438..503 CDD:319273 19/72 (26%)
FN3 511..606 CDD:238020 21/104 (20%)
FN3 622..706 CDD:238020 26/85 (31%)
Atrophin-1 <924..1361 CDD:331285 116/656 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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