DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam1 and Negr1

DIOPT Version :9

Sequence 1:NP_001246162.1 Gene:Dscam1 / 35652 FlyBaseID:FBgn0033159 Length:2038 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:306 Identity:74/306 - (24%)
Similarity:122/306 - (39%) Gaps:33/306 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   626 PFAYED--LINMGDSIDLFCQIQKGDRPIKVHWSFERSAGDYGFDQ--VQPQMRTNRISEKTSMI 686
            |:|..|  |:..||:..|.|.::.|  ..|..|....|....|.|:  |.|::..:.::::...:
Mouse    35 PWAAVDNMLVRKGDTAVLRCYLEDG--ASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSL 97

  Fly   687 SIPSASPAHTGRDTCIASNKAGTTTYSVDLTVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKP 751
            .|.:......|..||....:....|..|.|||.|||:......|....:|::..:.|.|.|.|:|
Mouse    98 QIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTINEGTNVTLTCLATGKPEP 162

  Fly   752 QVTWK----KAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIM 812
            .::|:    .|.....|:|.|               :..|.:...|.|.|.|.|.:.......:.
Mouse   163 VISWRHISPSAKPFENGQYLD---------------IYGITRDQAGEYECSAENDVSFPDVKKVR 212

  Fly   813 ISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTG 877
            :.|...|...| :::.|...|...:::||..|..|....|.....||  .|..:..|   |.:..
Mouse   213 VIVNFAPTIQE-IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKRL--FNGQQGII---IQNFS 271

  Fly   878 VMSSLSIKRTERSDSALFTCVATNAFGSDDAS--INMIVQEVPEMP 921
            ..|.|::....:.....:||||.|..|:.:||  :|.|::.....|
Mouse   272 TRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNQIIEPTTSSP 317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam1NP_001246162.1 Ig 38..130 CDD:299845
IG 57..133 CDD:214652
IG_like 267..343 CDD:214653
Ig 269..340 CDD:143165
IG_like 353..425 CDD:214653
IGc2 361..413 CDD:197706
I-set 433..527 CDD:254352
IGc2 446..517 CDD:197706
I-set 533..618 CDD:254352
IGc2 544..607 CDD:197706
Ig 641..714 CDD:143165 15/74 (20%)
IGc2 735..804 CDD:197706 17/72 (24%)
I-set 819..914 CDD:254352 25/96 (26%)
Ig 833..921 CDD:299845 23/89 (26%)
FN3 918..1011 CDD:238020 1/4 (25%)
FN3 1018..1116 CDD:238020
FN3 1124..1217 CDD:238020
FN3 1222..1312 CDD:238020
Ig 1339..1406 CDD:299845
FN3 1409..1499 CDD:238020
FN3 1504..1584 CDD:238020
Dscam_C 1890..2008 CDD:289151
Negr1XP_036019026.1 FR1 38..55 CDD:409353 5/16 (31%)
Ig strand A' 40..46 CDD:409353 2/5 (40%)
IG_like 41..129 CDD:214653 20/89 (22%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 1/5 (20%)
FR2 61..68 CDD:409353 2/6 (33%)
Ig strand C 61..67 CDD:409353 2/5 (40%)
CDR2 69..79 CDD:409353 3/9 (33%)
Ig strand C' 71..74 CDD:409353 0/2 (0%)
Ig strand C' 76..79 CDD:409353 1/2 (50%)
FR3 80..115 CDD:409353 6/34 (18%)
Ig strand D 84..91 CDD:409353 0/6 (0%)
Ig strand E 94..100 CDD:409353 0/5 (0%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 0/3 (0%)
Ig strand G 120..129 CDD:409353 3/8 (38%)
FR4 122..129 CDD:409353 3/6 (50%)
Ig strand A' 139..144 CDD:409353 1/4 (25%)
IGc2 146..204 CDD:197706 17/72 (24%)
Ig strand B 150..157 CDD:409353 1/6 (17%)
Ig strand C 163..168 CDD:409353 1/4 (25%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 2/20 (10%)
Ig strand F 193..200 CDD:409353 3/6 (50%)
Ig_3 219..295 CDD:404760 20/81 (25%)
putative Ig strand A 219..225 CDD:409353 2/6 (33%)
Ig strand B 235..239 CDD:409353 0/3 (0%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 2/4 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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