DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dscam1 and Bsg

DIOPT Version :9

Sequence 1:	NP_001246162.1	Gene:	Dscam1 / 35652	FlyBaseID:	FBgn0033159	Length:	2038	Species:	Drosophila melanogaster
Sequence 2:	NP_723346.2	Gene:	Bsg / 318841	FlyBaseID:	FBgn0261822	Length:	648	Species:	Drosophila melanogaster

Alignment Length:	164	Identity:	40/164 - (24%)
Similarity:	66/164 - (40%)	Gaps:	26/164 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   746 DGFPKPQVTWKK---AVGDTP---GEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIG 804
            ||.|...:.|||   ||.|.|   |.:|       :..:|....:|.....::|.|.|| .:|:.
  Fly   430 DGTPGGVLIWKKNGTAVTDVPSLRGRFK-------LIADENKFIIDKTDTNDDGKYSCE-FDGVS 486

  Fly   805 SGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTI 869
            ..:..:..:.|:.|       .|.....||...:.|...|.|| .:.|...|:.|....| |:.:
  Fly   487 KEIEVIARVVVRVP-------SNTAVVEGEKMSVTCSVVGTKP-ELTWTFANVTLTNATD-RFIL 542

  Fly   870 REEILSTGVMSS-LSIKRTERSDSALFTCVATNA 902
            :.:  ..||.:: |::......|...:.|:..||
  Fly   543 KPD--DNGVPNAILTLDNVTLDDRGEYKCIGRNA 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dscam1	NP_001246162.1	Ig	38..130	CDD:299845
		IG	57..133	CDD:214652
		IG_like	267..343	CDD:214653
		Ig	269..340	CDD:143165
		IG_like	353..425	CDD:214653
		IGc2	361..413	CDD:197706
		I-set	433..527	CDD:254352
		IGc2	446..517	CDD:197706
		I-set	533..618	CDD:254352
		IGc2	544..607	CDD:197706
		Ig	641..714	CDD:143165
		IGc2	735..804	CDD:197706	19/63 (30%)
		I-set	819..914	CDD:254352	19/85 (22%)
		Ig	833..921	CDD:299845	18/71 (25%)
		FN3	918..1011	CDD:238020
		FN3	1018..1116	CDD:238020
		FN3	1124..1217	CDD:238020
		FN3	1222..1312	CDD:238020
		Ig	1339..1406	CDD:299845
		FN3	1409..1499	CDD:238020
		FN3	1504..1584	CDD:238020
		Dscam_C	1890..2008	CDD:289151
Bsg	NP_723346.2	IG_like	420..497	CDD:214653	19/74 (26%)
		Ig	423..497	CDD:299845	19/74 (26%)
		IG_like	500..583	CDD:214653	20/86 (23%)
		Ig	512..575	CDD:143165	16/67 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10075
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100