|
Fly 419 EASAELKLGGRFD---------------PPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWEL 468
:.|..:.|.|.|: |.::.|. .:..:..|....|.|.|.|.|.|.|.|..
Rat 49 DPSLNVALPGHFELPPSPGSRVGPEDAMPRIVEQP-PDLLVSRGEPATLPCRAEGRPRPNIEWYK 112
Fly 469 DGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHAN----DGGLYKCIAKSKVG-VAEHSAKLNVY 528
:|.::|..........:.:....:.:..| ||.. |.|:|.|:|::.:| .|..:|.|.|.
Rat 113 NGARVATAREDPRAHRLLLPSGALFFPRI--VHGRRSRPDEGVYTCVARNYLGAAASRNASLEVA 175
Fly 529 GL-PYIRQMEKKAIVA-GETLIVTC-PVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVE 590
.| ...||.....:|| ||..::.| |..|:|...:.|::.|..|.....:.....|.|::.:..
Rat 176 VLRDDFRQSPGNVVVAVGEPAVMECVPPKGHPEPLVTWKKGNTKLKEEEGRITIRGGKLMMSHTF 240
Fly 591 RNSDQATYTCVAKNQEGYSARGSLEVQVMVLPQIVPFAYEDLINMGDSIDLFCQIQKGDRPIKVH 655
: ||...|.|||.|..|....|:.|:.|:..|..:......::.....::..|::| ||....:.
Rat 241 K-SDAGMYMCVASNMAGERESGAAELVVLERPSFLRRPINQVVLADAPVNFLCEVQ-GDPQPNLR 303
Fly 656 W---SFERSAGDYGFDQVQPQMRTNRISEKTSMISIPSASPAHTGRDTCIASNKAGTTTYSVDLT 717
| ..|...|.| ::|::. .:.|...|....|..||:|.|..|....|..|:
Rat 304 WRKDDGELPTGRY-------EIRSDH------SLWIEQVSAEDEGTYTCVAENSVGRAEASGSLS 355
Fly 718 VNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDT---PGEYKDLKKSDNIRVE- 778
|:|||:::.:|.::..|.|.:...:|:..|.|.|.:.|:|..... |.: .|:....:.|.
Rat 356 VHVPPQFVTKPQNQTAAPGENVSFQCETKGNPPPAIFWQKEGSQVLLFPSQ--SLQPMGRLLVSP 418
Fly 779 EGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIM----ISVQA-PPEFTEKLRNQTARRGEPAVL 838
.|.|::..::..:.|||:|:|::..||.|:..:: .|:.. ||...:...|||...|....|
Rat 419 RGQLNITEVKIGDGGYYVCQAVSVAGSILAKALLEIKGASIDGLPPIILQGPANQTLVLGSSVWL 483
Fly 839 QCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAF 903
.|...|.....:.|..:...|...| :::.:.:. .:|.|...:..|...::|||.::.
Rat 484 PCRVIGNPQPNVQWKKDETWLQGDN-SQFNLMDN-------GTLYIASVQEMDMGFYSCVAKSSI 540
Fly 904 GSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRV 968
| :|:.| ||. |.|..|.
Rat 541 G--EATWN-------------------------SWL-----------------RKREHWG----- 556
Fly 969 IVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTM 1033
..||..|| |.. |.|.|....|..|...::
Rat 557 ASPGPATE-------PGN-----------------------------PPGPPSQPIVTEVTTNSI 585
Fly 1034 RVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFE--------TINFITEEGKEHNLELQNLRVY 1090
.:||||.|:: |.:. :|||.| |...:.:..:.....:..|:..
Rat 586 TLTWKPNPQS-----------GARA----TSYVIEAFSQAAGNTWRTVADGVQLETHTVSGLQPN 635
Fly 1091 TQYSVVIQAFNKIGAGPLSE----EEKQFTAEGTPSQPPSD---------------TACTTLTSQ 1136
|.|..:::| :||..||| .|...|.:.:.|:|..| .....|..:
Rat 636 TIYLFLVRA---VGAWGLSEPSPVSEPVQTQDSSLSRPVEDPWKGQQGLAEVAVRMQEPIVLGPR 697
Fly 1137 TIRVGW-VSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLA 1200
|::|.| |..|.:...|...::::.......| |....:......|||.||...:...::|..
Rat 698 TLQVSWTVEGPGQLVQGFRVSWRIAGLDQGSW---TALDVQSPHKQSTVLRGLPPGSQIQIKVQV 759
Fly 1201 TTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMG---NAAILVSWRP--PAQPNGIITQYTVYSK 1260
....|.|..|..:......:.|..|....|:.:| |::|.|||.| |:|.||:||:|.::
Rat 760 QGQEGLGAESPSVTRSIPEEAPSGPPQGVAVALGGDRNSSITVSWEPPLPSQQNGVITEYQIW-- 822
Fly 1261 AEGAETETK-TQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIAS 1324
..|.|:... .:....:..|.....|.....|...|.|:|:.|.|..|..::
Rat 823 CLGNESRFHLNRSAAGWARSVMFRGLLPGLLYRAIVAAATSAGVGVASAPVL------------- 874
Fly 1325 FDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPD-----------GSLLI-- 1376
.::|...|..|.||:: |..|....|||.. |:||:
Rat 875 ------------VQLPFPPVAEPGPEVS------EGLAERLSRVLRKPAFLAGSSAACGALLLGL 921
Fly 1377 ------KSVNRQDAGDYSC-----------HAENSIAKDSITHKLIVLAPPQS------------ 1412
:...|::...|:. |:|......| .||..
Rat 922 CAALYRRQKQRKELSHYTASFAYTPAVSFPHSEGLSGSSS--------RPPMGLGPAAYPWLADS 978
Fly 1413 -PHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRY 1476
||.:.|.:..:. .|...| |....|.:.:|..|: |.|
Rat 979 WPHPSRSPSAQEP--------RGSCCP-----------------SNPDPDDRYYNEAGI---SLY 1015
Fly 1477 QVY-ATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVE 1540
... |.|.|..|.|.....:: .|.....:.| ||.| .|...:
Rat 1016 LAQTARGANAPGEGPVYSTID-----------------PVGEELQTFH------GGFP-QHSSGD 1056
Fly 1541 SKKRDQI---EWNQISNNVKPDNNYVV---LDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTG 1599
.....|. ||::..:..:.....:: :.:...:|.........|...:..|
Rat 1057 PSTWSQYAPPEWSEGDSGARGGKGKLLGKPVQMPSLSWPEALPPPPPSCELSCPE---------- 1111
Fly 1600 GTIAPLDDGSGHGNVHTRIRLPAWMPEWLDLNFMVPLIATVVVVAVGICVVCVALSRRRADDMRG 1664
.|.::..|..: |..|.|...:...::...:: |.|:|..|.....:.....
Rat 1112 ---GPEEELKGSSD------LEEWCPPMPEKKHLIDSRSS------GACMVAPARGETPSPTSSY 1161
Fly 1665 GQKDVYYDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRS 1729
||:.. |||....|| ||.|.|:.
Rat 1162 GQQST-------------ATLTPSPPD---------------PPQPPSDI--------------- 1183
Fly 1730 NHSTWDPRR---NPNLYEELKAPPVPMH-GNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFR 1790
.|....||| .|:....:..|.:..| |...|...| |..::|
Rat 1184 PHLHQMPRRVPLGPSSPLSVSQPALSSHDGRPVGLGAG----------------PIVSYH----- 1227
Fly 1791 EEMDPTKAMNFQTFPHQNGHAGPVPGHA-----------GTMLPPGHPGHVHSRSGSQSMPRANR 1844
|:.: |||..| |.|.||.|......|..::::|
Rat 1228 ----PSPS--------------PVPSTASSAPGRTRQVTGEMTPPLHGHRARIRKKTKALP---- 1270
Fly 1845 YQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSL---YSG-------------- 1892
::|::|.|.......|.|| ||..:....|......|| :||
Rat 1271 HRREHSPGDLPPPPLPPPE--------EETSWPLGLRAAGSMSSLEREHSGERRVAQAVPLGAQP 1327
Fly 1893 PGPE---YDDPA--NCAPEEDQYGSQYGGPYGQP-YDHYG-------------SRGSMGRRSIGS 1938
||.: :.|.| .||.||... |||:| :..:| ||||...|....
Rat 1328 PGAQRGPHPDAALLGCAAEEAWL------PYGRPSFLSHGQGTSTCSTAGSNSSRGSNSSRGSRG 1386
Fly 1939 ARNPGNG---SPEPPPPPPRN 1956
:|.||.. |......|.||
Rat 1387 SRGPGRSRSRSQSQSQRPGRN 1407
| 
