DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam1 and Lsamp

DIOPT Version :9

Sequence 1:NP_001246162.1 Gene:Dscam1 / 35652 FlyBaseID:FBgn0033159 Length:2038 Species:Drosophila melanogaster
Sequence 2:XP_038944182.1 Gene:Lsamp / 29561 RGDID:71102 Length:378 Species:Rattus norvegicus


Alignment Length:314 Identity:83/314 - (26%)
Similarity:134/314 - (42%) Gaps:30/314 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   633 INMGDSIDLFCQIQKGDRPIKVHWSFERSAGDY-GFDQ--VQPQMRTNRISEKTSMISIPSASPA 694
            :..||:..|.|.::  |:..||.| ..||...: |.|:  :.|::...:.......:.|......
  Rat    60 VRQGDTAILRCVVE--DKNSKVAW-LNRSGIIFAGHDKWSLDPRVELEKRHALEYSLRIQKVDVY 121

  Fly   695 HTGRDTCIASNKAGTTTYSVDLTVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAV 759
            ..|..||....:....|..|.|.|.|||:.....:|....:||:..:.|.|:|.|:|.:||:.. 
  Rat   122 DEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITWRHL- 185

  Fly   760 GDTP--GEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFT 822
              ||  .|::.         ||..|.:..|.:...|.|.|:|.|.:.|.....:.::|..||..|
  Rat   186 --TPLGREFEG---------EEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTIT 239

  Fly   823 EKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRT 887
            |...|: |..|..|.|:|||.........|..::.|::..|.      .||.||...|||::...
  Rat   240 ESKSNE-ATTGRQASLKCEASAVPAPDFEWYRDDTRINSANG------LEIKSTEGQSSLTVTNV 297

  Fly   888 ERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQP 941
            .......:||||.|..|..:||:.:..:.:|.:|:.::.:   |.:|......|
  Rat   298 TEEHYGNYTCVAANKLGVTNASLVLFKRVLPTVPHPIQEI---GTTVHFKQKGP 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam1NP_001246162.1 Ig 38..130 CDD:299845
IG 57..133 CDD:214652
IG_like 267..343 CDD:214653
Ig 269..340 CDD:143165
IG_like 353..425 CDD:214653
IGc2 361..413 CDD:197706
I-set 433..527 CDD:254352
IGc2 446..517 CDD:197706
I-set 533..618 CDD:254352
IGc2 544..607 CDD:197706
Ig 641..714 CDD:143165 16/75 (21%)
IGc2 735..804 CDD:197706 21/70 (30%)
I-set 819..914 CDD:254352 29/94 (31%)
Ig 833..921 CDD:299845 25/87 (29%)
FN3 918..1011 CDD:238020 5/24 (21%)
FN3 1018..1116 CDD:238020
FN3 1124..1217 CDD:238020
FN3 1222..1312 CDD:238020
Ig 1339..1406 CDD:299845
FN3 1409..1499 CDD:238020
FN3 1504..1584 CDD:238020
Dscam_C 1890..2008 CDD:289151
LsampXP_038944182.1 Ig 55..145 CDD:416386 20/87 (23%)
FR1 55..71 CDD:409353 3/10 (30%)
Ig strand A' 56..62 CDD:409353 0/1 (0%)
Ig strand B 64..72 CDD:409353 3/7 (43%)
CDR1 72..76 CDD:409353 1/5 (20%)
FR2 77..84 CDD:409353 3/7 (43%)
Ig strand C 77..83 CDD:409353 3/6 (50%)
CDR2 85..95 CDD:409353 3/9 (33%)
Ig strand C' 87..90 CDD:409353 0/2 (0%)
Ig strand C' 92..95 CDD:409353 1/2 (50%)
FR3 96..131 CDD:409353 5/34 (15%)
Ig strand D 100..107 CDD:409353 0/6 (0%)
Ig strand E 110..116 CDD:409353 0/5 (0%)
Ig strand F 123..131 CDD:409353 3/7 (43%)
CDR3 132..136 CDD:409353 0/3 (0%)
Ig strand G 136..145 CDD:409353 3/8 (38%)
FR4 138..145 CDD:409353 3/6 (50%)
Ig_3 148..218 CDD:404760 23/81 (28%)
Ig strand A' 155..160 CDD:409353 1/4 (25%)
Ig strand B 166..173 CDD:409353 1/6 (17%)
Ig strand C 179..184 CDD:409353 2/4 (50%)
Ig strand D 190..193 CDD:409353 1/2 (50%)
Ig strand E 197..203 CDD:409353 1/5 (20%)
Ig strand F 210..217 CDD:409353 3/6 (50%)
Ig strand G 224..232 CDD:409353 0/7 (0%)
Ig_3 235..311 CDD:404760 26/82 (32%)
Ig strand B 252..256 CDD:409353 2/3 (67%)
Ig strand C 265..269 CDD:409353 0/3 (0%)
Ig strand E 290..294 CDD:409353 3/3 (100%)
Ig strand F 304..309 CDD:409353 2/4 (50%)
Ig strand G 318..321 CDD:409353 2/2 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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