DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam1 and Iglon5

DIOPT Version :9

Sequence 1:NP_001246162.1 Gene:Dscam1 / 35652 FlyBaseID:FBgn0033159 Length:2038 Species:Drosophila melanogaster
Sequence 2:NP_001157990.1 Gene:Iglon5 / 210094 MGIID:2686277 Length:336 Species:Mus musculus


Alignment Length:324 Identity:87/324 - (26%)
Similarity:129/324 - (39%) Gaps:60/324 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   636 GDSIDLFCQIQKGDRPIKVHWSFERSAGDY-GFDQ--VQPQMRTNRISEKTSMISIPSASPAHTG 697
            ||:..|.|.|.  :...:|.| ..||...| |.|:  ..|::|....:.:...|.|........|
Mouse    47 GDNATLSCFID--EHVTRVAW-LNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITQVGLGDEG 108

  Fly   698 RDTCIASNKAGTTTYSVDLTVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDT 762
            ..||....:....|..|.|.|:||.|.:...:..|..:|.:..:.|.|.|.|:|.|||::.    
Mouse   109 LYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVAVNEGGNVNLLCLAVGRPEPTVTWRQL---- 169

  Fly   763 PGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGL-SAVIMISVQAPPEFTEKLR 826
                     .|....|...|.:.:||:...|.|.|...||:.|.. |..::::|..||..|:...
Mouse   170 ---------RDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTS 225

  Fly   827 NQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSD 891
            .:|| .|..|:|:|||....|....|.        |:|       .:||:|....|.: :|||:.
Mouse   226 ARTA-LGRAALLRCEAMAVPPADFQWY--------KDD-------RLLSSGSAEGLKV-QTERTR 273

  Fly   892 SAL------------FTCVATNAFGSDDASINM-----IVQEVPEMPYALKVLDKSGRSVQLSW 938
            |.|            :||.|.|..|:..||:.:     :....|..|..|.:|.      .|||
Mouse   274 SMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAPRPPGPLTLLS------ALSW 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam1NP_001246162.1 Ig 38..130 CDD:299845
IG 57..133 CDD:214652
IG_like 267..343 CDD:214653
Ig 269..340 CDD:143165
IG_like 353..425 CDD:214653
IGc2 361..413 CDD:197706
I-set 433..527 CDD:254352
IGc2 446..517 CDD:197706
I-set 533..618 CDD:254352
IGc2 544..607 CDD:197706
Ig 641..714 CDD:143165 18/75 (24%)
IGc2 735..804 CDD:197706 19/68 (28%)
I-set 819..914 CDD:254352 30/111 (27%)
Ig 833..921 CDD:299845 27/104 (26%)
FN3 918..1011 CDD:238020 7/21 (33%)
FN3 1018..1116 CDD:238020
FN3 1124..1217 CDD:238020
FN3 1222..1312 CDD:238020
Ig 1339..1406 CDD:299845
FN3 1409..1499 CDD:238020
FN3 1504..1584 CDD:238020
Dscam_C 1890..2008 CDD:289151
Iglon5NP_001157990.1 Ig 41..129 CDD:416386 22/84 (26%)
Ig strand A' 41..46 CDD:409353
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 1/5 (20%)
FR2 61..68 CDD:409353 2/7 (29%)
Ig strand C 61..67 CDD:409353 2/6 (33%)
CDR2 69..79 CDD:409353 4/9 (44%)
Ig strand C' 71..74 CDD:409353 0/2 (0%)
Ig strand C' 76..79 CDD:409353 1/2 (50%)
FR3 80..115 CDD:409353 7/34 (21%)
Ig strand D 84..91 CDD:409353 1/6 (17%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 0/3 (0%)
Ig strand G 120..129 CDD:409353 3/8 (38%)
FR4 122..129 CDD:409353 3/6 (50%)
Ig strand A 132..137 CDD:409353 2/4 (50%)
Ig_3 134..199 CDD:404760 19/77 (25%)
Ig strand A' 140..145 CDD:409353 1/4 (25%)
Ig strand B 148..157 CDD:409353 1/8 (13%)
Ig strand C 163..167 CDD:409353 2/3 (67%)
Ig strand D 174..177 CDD:409353 0/2 (0%)
Ig strand E 178..183 CDD:409353 1/4 (25%)
Ig strand F 191..199 CDD:409353 3/7 (43%)
Ig_3 217..295 CDD:404760 27/94 (29%)
putative Ig strand A 218..224 CDD:409353 2/5 (40%)
Ig strand B 234..238 CDD:409353 2/3 (67%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 2/4 (50%)
Ig strand G 301..304 CDD:409353 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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