DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam1 and zig-8

DIOPT Version :9

Sequence 1:NP_001246162.1 Gene:Dscam1 / 35652 FlyBaseID:FBgn0033159 Length:2038 Species:Drosophila melanogaster
Sequence 2:NP_499714.1 Gene:zig-8 / 176732 WormBaseID:WBGene00006985 Length:268 Species:Caenorhabditis elegans


Alignment Length:239 Identity:53/239 - (22%)
Similarity:90/239 - (37%) Gaps:57/239 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   325 LCVVNNS----VGGESVETVLTVTAPLSAKIDPPTQT---VDFGRPAVFTCQYTGNPIKTVSW-- 380
            :||:..|    .|..:.|.|:.......::::.|:||   |....||...|....:....::|  
 Worm     7 ICVILFSFLYATGHGASEEVMACLRQERSRVENPSQTIVNVVAENPAYLHCSVPPDAEHEIAWTR 71

  Fly   381 MKDGKAI--GH----SEP------------VLRIESVKKEDKGMYQCFVRNDQESAEASAELKLG 427
            :.||..:  |:    .:|            ||.:...:::|.|.|.|.: ||:.:...:..||: 
 Worm    72 VSDGALLTAGNRTFTRDPRWQVSKKSANIWVLNLRRAEQQDSGCYLCEI-NDKHNTVYAVYLKV- 134

  Fly   428 GRFDPPV-IRQAFQEETME-----PGPSVFLKCVAGGNPTPE----ISWELDGKKIANNDRYQVG 482
              .:||: ...:.|:::.:     .|..|.|.|........|    :.|..||..|..||   ..
 Worm   135 --LEPPLPSPSSLQKKSTKLMANMSGDEVVLNCTVTSTDKDEEVLDVVWTRDGNTINFND---TE 194

  Fly   483 QYVTV----NGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHS 522
            :|:..    .|.|:..:.|......|.|.|.|         |||
 Worm   195 KYILKVKRDAGVVIETMRIRKATMEDDGNYAC---------EHS 229

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam1NP_001246162.1 Ig 38..130 CDD:299845
IG 57..133 CDD:214652
IG_like 267..343 CDD:214653 6/21 (29%)
Ig 269..340 CDD:143165 5/18 (28%)
IG_like 353..425 CDD:214653 20/94 (21%)
IGc2 361..413 CDD:197706 14/71 (20%)
I-set 433..527 CDD:254352 24/104 (23%)
IGc2 446..517 CDD:197706 19/78 (24%)
I-set 533..618 CDD:254352
IGc2 544..607 CDD:197706
Ig 641..714 CDD:143165
IGc2 735..804 CDD:197706
I-set 819..914 CDD:254352
Ig 833..921 CDD:299845
FN3 918..1011 CDD:238020
FN3 1018..1116 CDD:238020
FN3 1124..1217 CDD:238020
FN3 1222..1312 CDD:238020
Ig 1339..1406 CDD:299845
FN3 1409..1499 CDD:238020
FN3 1504..1584 CDD:238020
Dscam_C 1890..2008 CDD:289151
zig-8NP_499714.1 IG_like 55..134 CDD:214653 15/79 (19%)
Ig 55..129 CDD:143165 14/74 (19%)
ig 158..229 CDD:278476 20/82 (24%)
IG_like 158..227 CDD:214653 19/80 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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