Protein Alignment Dscam1 and il6st

DIOPT Version :9

• Sequence 1: NP_001246162.1
• Gene: Dscam1 / 35652
• FlyBaseID: FBgn0033159
• Length: 2038
• Species: Drosophila melanogaster
• Sequence 2: XP_012822352.2
• Gene: il6st / 100489642
• XenbaseID: XB-GENE-855663
• Length: 939
• Species: Xenopus tropicalis
• Alignment Length: 979
• Identity: 182/979 - (18%)
• Similarity: 305/979 - (31%)
• Gaps: 317/979 - (32%)

  Fly   672 PQMRTNRISEKTSMISIPS----ASPAHTGRDTC--IASNKAGTTTYSVDLTVNVPPRWILEPTD 730
            |:.:...::...|.::..:    .||.     ||  :.|.:...|.|.:..||.:||.   :|.:
 Frog    72 PETQYKVVNHTVSSVTFENPATLVSPL-----TCSVLVSGQVEQTLYGIFFTVALPPD---QPKN 128

  Fly   731 KAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYY 795
            ......:...:.|          ||      .||...:|                     |..|.
 Frog   129 LTCVAYNQDNLTC----------TW------DPGRPTNL---------------------NTNYT 156

  Fly   796 LCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVL-------QCEAKGEKPIGILWN 853
            |....|.:.                       .||.||...|.       ...|:|.|     |.
 Frog   157 LMHRWNPLA-----------------------LTAERGSELVQNKVKSLPSARARGRK-----WT 193

  Fly   854 MNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSAL------------FTCVATNAFGSD 906
            :      ||:....:..:::....:..:..|.:...:...:            |...|.|..||.
 Frog   194 L------PKHGYTNSEGDQMFRANIQKNYCIPKESNNSCTVRYPDFQFFVDTTFQVEAKNELGSQ 252

  Fly   907 DAS------INMIVQEVP---------EMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFK 956
            ::.      :|::....|         |:|.|||:          .|..|.  |:...:|.|.::
 Frog   253 ESEVLTVDPVNIVKPNPPQLSDLISAVELPNALKI----------KWKNPI--NAFKLKYNIRYR 305

  Fly   957 R-SRASWSEIDRVIVPGHTTEAQVQKLSPATTY--NIRIVAENAIG-TSQSSEAVTIITAEEAPS 1017
            . ....|..:.......|.....:|.|.|.|.|  :||.:.|:..| .|..||....:|.|..||
 Frog   306 PIKNQDWEMVPEEDTASHRDSFTLQDLLPYTEYEVSIRCIKEDGRGFWSDWSEVKKQVTPEAQPS 370

  Fly  1018 GKP---QNI-KVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGK 1078
            ..|   :|: ..:......:.:.||....:..||:||.|.|.::..:.:.::.....::.....|
 Frog   371 RGPDVWKNVDSPDADGNRDVTIMWKALGDSVANGKILLYGVTFQSRSQSKTFNVTETSYKISLSK 435

  Fly  1079 EHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQ--PPSDTACTTLT------- 1134
            |.|.            |.:.|:|...|.|             |::  .|...:|..|.
 Frog   436 EINY------------VSVTAYNSRFASP-------------PAKLNIPRSGSCQVLAPELSVKA 475

  Fly  1135 ---SQTIRVGWVSPPLESANGVIKTYKVVYAP---SDEWYDETKRHYKKTASSDTVLHG----LK 1189
               .:.:.|.| :|..::.:|.|..:...||.   ..:|..|.:      ::..|.|.|    ||
 Frog   476 YPKEEQLWVEW-NPQNKNLDGYIIEWCNKYAKEGCDSDWQREPR------SAQSTFLRGELEPLK 533

  Fly  1190 KYTNYTMQVLATTAGGDGVRSV-PIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPA--QPNGI 1251
            .|.....|:..     ||..|| .:....:...|.....|....:.....::.|.|..  :.||.
 Frog   534 CYLIKVYQLFK-----DGCESVAAVEAYLQQGTPSVGPSVHTKQVEKYKAILQWTPVPFDKQNGF 593

  Fly  1252 ITQYTV-YSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPS 1315
            |..||: |..:.|.||   |..:......:..:.|:.|..|...:.|.|..| |:.....
 Frog   594 IKNYTLTYKASHGNET---TLVIDPLDTEYTLSGLDGNTLYSVHMVAYTEKG-GKDGPVF----- 649

  Fly  1316 DQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRV-------LPDGS 1373
                        |||.....:.::..:.|.:....:...:.||....|.|..:       :||.|
 Frog   650 ------------TFTTLKFANGEVEAIVVSSCVAFLILVLIGVMLCFNHRDLIKKHIWPNVPDPS 702

  Fly  1374 LLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSP---------HVTLSATTTDALTVKL 1429
                              :::||:.|          ||:|         |.....:.||...|::
 Frog   703 ------------------KSNIAQWS----------PQTPSRHDFNAKAHPFQDGSFTDVSVVEI 739

  Fly  1430 KPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNI-EGLLCG---------SRYQV------ 1478
                         |......|.|.:..  |:|..|.|. |||..|         .|..|
 Frog   740 -------------TAENPKSFSEQDIK--SMDPMKKNTSEGLSSGIGGSSCMSSPRLSVSDCDEV 789

  Fly  1479 -----------YAT----GFNNIGAGEASDILNTRTKGQKPKL-----PEKPRFI--EVSSNSVS 1521
                       |:|    |:.:......|..:.:|::..:|.|     ||:|..:  |.|....:
 Frog   790 ESAQTTSSTVQYSTVIISGYRDQQPTAVSPHIFSRSESTQPLLDCEERPEEPNAVDKEGSPEGAN 854

  Fly  1522 LHFK 1525
            .:||
 Frog   855 QYFK 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dscam1	NP_001246162.1	Ig	38..130	CDD:299845
		IG	57..133	CDD:214652
		IG_like	267..343	CDD:214653
		Ig	269..340	CDD:143165
		IG_like	353..425	CDD:214653
		IGc2	361..413	CDD:197706
		I-set	433..527	CDD:254352
		IGc2	446..517	CDD:197706
		I-set	533..618	CDD:254352
		IGc2	544..607	CDD:197706
		Ig	641..714	CDD:143165	9/47 (19%)
		IGc2	735..804	CDD:197706	10/68 (15%)
		I-set	819..914	CDD:254352	18/119 (15%)
		Ig	833..921	CDD:299845	17/121 (14%)
		FN3	918..1011	CDD:238020	25/105 (24%)
		FN3	1018..1116	CDD:238020	18/101 (18%)
		FN3	1124..1217	CDD:238020	23/110 (21%)
		FN3	1222..1312	CDD:238020	21/92 (23%)
		Ig	1339..1406	CDD:299845	11/73 (15%)
		FN3	1409..1499	CDD:238020	24/129 (19%)
		FN3	1504..1584	CDD:238020	9/29 (31%)
		Dscam_C	1890..2008	CDD:289151
il6st	XP_012822352.2	Lep_receptor_Ig	26..109	CDD:399379	7/41 (17%)
		FN3	128..>164	CDD:419708	10/72 (14%)
		FN3	267..360	CDD:238020	25/104 (24%)
		FN3	562..642	CDD:214495	19/82 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910