DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam1 and igsf9b

DIOPT Version :9

Sequence 1:NP_001246162.1 Gene:Dscam1 / 35652 FlyBaseID:FBgn0033159 Length:2038 Species:Drosophila melanogaster
Sequence 2:XP_031761656.1 Gene:igsf9b / 100379858 XenbaseID:XB-GENE-5887265 Length:1392 Species:Xenopus tropicalis


Alignment Length:1622 Identity:338/1622 - (20%)
Similarity:523/1622 - (32%) Gaps:554/1622 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   334 GESVETVLTVTAPLSAKIDPPTQTVD---FGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLR 395
            ||||.....|..||:  :.||...|:   ||.|.....::...| ..|.....|:|..:.:..||
 Frog    38 GESVILGCDVVHPLT--VQPPPYVVEWFKFGVPIPIFIKFGFYP-PHVDPEYVGRAALYDKASLR 99

  Fly   396 IESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFD--------------PPVIRQA-FQEETME 445
            ||.|:.:|:|.|:|.|            |.|..::|              ||...:. .|...::
 Frog   100 IEQVRSQDQGWYECKV------------LMLEHQYDTFHNGSWVHLTVNAPPTFTETPPQYLEVK 152

  Fly   446 PGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKC 510
            .|.|:.|.|.|.|||.|.:||..:|:.:....:||:..         ..|.|:|:...|.|.|.|
 Frog   153 EGSSITLTCTAFGNPKPTVSWLREGEFLGRTSKYQLSD---------GSLTISSIGREDRGSYMC 208

  Fly   511 IAKSKVGVAEHSAKLNVYGLPYI-RQMEKKAIVAGETLIVTCPVAGYPID---SIVWERDNRAL- 570
            .|.|..|.|.||.:|.|.|.|:| ...|...:...:..:.||....||.:   :..|:.:|... 
 Frog   209 RATSIQGEAVHSTRLLVQGSPFIVSPPENITVNISQDALFTCQAEAYPGNLTYTWYWQEENVFFK 273

  Fly   571 -PINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVLPQIVPFAYEDLIN 634
             .:..:.::..:|||||..| :..|...||||..|..|.|                         
 Frog   274 NDLKLRVRILIDGTLIIFRV-KPEDAGKYTCVPSNSLGRS------------------------- 312

  Fly   635 MGDSIDLFCQIQKGDRPIKVHWSFERSAGDYGFDQVQPQMRTNRISEKTSMISIPSASPAHTGRD 699
                                                                  ||||       
 Frog   313 ------------------------------------------------------PSAS------- 316

  Fly   700 TCIASNKAGTTTYSVDLTVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQ-VTWKKAVGDTP 763
                       .|   |||..|.|.:..|.......|....:.|..:..|... |.|.|     .
 Frog   317 -----------AY---LTVQYPARVVNMPPVIYVPVGIHGHIRCPVEAVPPVTFVKWNK-----D 362

  Fly   764 GEYKDLKKSDNIR-VEEGTLHVDNIQKTNEGYYLCEAINGIGS-GLSAVIMISVQAPPEFTE--- 823
            |....:.|....: :::||:||:...:...|.|.|...|.:|: |.|....:.::.||.||.   
 Frog   363 GRPLRIDKFSGWKLLDDGTIHVEEATEELLGTYTCVPYNALGTMGQSPPARLLLKDPPYFTVLPG 427

  Fly   824 -KLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRT 887
             :.|.:.   |...::.|.|.|:....|.|.        |.......:..:|.:|   ||..:..
 Frog   428 WEYRQEA---GRELLIPCAAAGDPFPSISWR--------KVGRPSFSKHSVLPSG---SLQFRSL 478

  Fly   888 ERSDSALFTCVATNAFGSDDASINM-IVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRY 951
            .:.|...:.|||:|...|..||.:: ::...|..|..::|: .|..:..:||...|||.      
 Frog   479 SKEDHGEWECVASNVVTSITASAHLTVIGTSPHAPSNVRVV-VSMNTANVSWEAGYDGG------ 536

  Fly   952 IIEFKRSRASW--SEIDR----------VIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSS 1004
               |:::.:.|  :.|.|          :.||..::...|..|.|.|.|...::|:|.:|||..|
 Frog   537 ---FEQTFSVWYGALIKRAQFGPHDWVSMPVPSGSSFLLVDSLDPETEYQFSVLAQNKLGTSSFS 598

  Fly  1005 EAVTIIT-AEEAPSGKPQNIKVEP----VNQTTMRV--TWKPPPR---------------TEW-- 1045
            |.||:.| |....:.:|..:...|    .|:|...|  :|.||..               ..|  
 Frog   599 EVVTLRTLAFPLTTPEPLLVLTSPRCLTANRTQQGVLLSWLPPSNHSFPLDRYIMEFRLAERWEI 663

  Fly  1046 --------NGEILGYYVGY--------------------KLSNTNSSYVFETINFITEEGKEHNL 1082
                    :.|||...:..                    .::..:||.||.:.: ::|||....:
 Frog   664 LDDSILGSDTEILAKELSQDTWYEFRVLAVMQDLISEPSNIAGVSSSDVFPSPD-LSEEGFARPV 727

  Fly  1083 ELQNLRVYTQYSVVIQAFNKIGAGPLSEEEK-----QFTAEGTPSQPP-SDTACTTLTSQTIRVG 1141
             |..:.....:......|:.:.|..::.:.|     :..:...|:.|| |.|.|.......:..|
 Frog   728 -LAGIVATICFLAAAILFSTLAACVVNRQRKRKMKRKKVSHSCPTDPPLSITHCRKSMESPLSSG 791

  Fly  1142 WVSPPLESANGVIKTYKVVYAPSDEWYDE---TKRH-----------YKKTASSDTVLHGLKKYT 1192
            .|||         ::.:.:.|||:...|:   :||.           ||||..:.|    .|||:
 Frog   792 KVSP---------ESVRTLRAPSESSEDQGPPSKRPLSPGREKELSLYKKTKRAMT----SKKYS 843

  Fly  1193 NYTMQVLATT------AGGDGVRSVPIHCQTEPDV--------PEA-PTDVKALVMGNAAILVSW 1242
            ....:...||      .|.|| |.|....:.||.:        |.| .||:      ......|.
 Frog   844 VSQAEAEVTTPIELISRGPDG-RFVTAGPEQEPTLRSRRIQGFPFAEETDM------YPEFRQSD 901

  Fly  1243 RPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQS 1307
            ....:|:|:.:|.|..|.::.:..:.     |.|...|:      ::|           .||:|.
 Frog   902 EENDEPSGLKSQLTPLSSSQDSPLQP-----PAYSPRFQ------HQP-----------SEGRQQ 944

  Fly  1308 KSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDG 1372
            .|..:.|.......:..:  ..::....|...|..     .||:: .:..|..|.    .:||:|
 Frog   945 PSGQSRPGGYHHGHLYGY--LSSSPLDSDPPPPFY-----MPEVS-PLSSVMSSP----PLLPEG 997

  Fly  1373 SL-LIKSVNRQDAGDYSCHAENSIAKD-SITHKLIVLAP-----------PQSPHVTLSATTTDA 1424
            |. .|...|          .|||.... .:||     .|           |..|.|.|.|..:.:
 Frog   998 SFPPIPEEN----------GENSSTSTLPLTH-----TPTGGRSPEQWGVPDFPFVGLEAPASPS 1047

  Fly  1425 LTVKLKPHEGDTA----------PL---HGY----TLHY------------------------KP 1448
            |.|:   |..:|.          ||   ||:    :|..                        .|
 Frog  1048 LFVQ---HRYETTEIRRPLPPPPPLPFPHGHPPPSSLQVPSYAAILPLESHPGWVGRLPSRCPPP 1109

  Fly  1449 EFGEWETSEVSVDSQ---KHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKP 1510
            ....|:.:.:.:.:|   :|..:|:  |.....|                        |.:|:  
 Frog  1110 PHPSWQDAAMQLAAQGQLRHTSQGM--GIPVLPY------------------------PDIPQ-- 1146

  Fly  1511 RFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLD---LEPATW 1572
                              .|...|.....||:.|.|:...| ...:.|..:.|||.   |.|.|.
 Frog  1147 ------------------PGPLGMDARWFESRPRPQMSPRQ-HRRLDPSLHQVVLQPSRLSPLTQ 1192

  Fly  1573 YNLRITAHNSAGFTVAEYDFATLTVTGGTIAPLDDGSG-----------------------HGNV 1614
            ..|. :.|.|...:|      ......|.:.|..|.||                       ||..
 Frog  1193 SPLS-SRHGSPELSV------RARPRPGLLPPPSDCSGIALQPPGFIHKSPPSSGSPAKSSHGES 1250

  Fly  1615 HT-RIRLPAWMP----------EWLDLNFMVPLIATVVVVAVGICVVCV---------------- 1652
            .: |:..|...|          |.|...       |.|:...|:.:..|                
 Frog  1251 PSYRLTPPDTSPHAEGRRRIGEERLHAE-------TAVLCTAGVGIAAVPERSEVVIDQRVLKPK 1308

  Fly  1653 ------ALSRRRADDMRGGQKDVYY--DVVYNQTMGPGATLDKRRPD----------LRDEL 1696
                  :.||:.:|   |....||.  ..||..|.   ....|:||.          |||||
 Frog  1309 KSTKGRSKSRKHSD---GSTSQVYQLPQAVYMDTR---CVRRKKRPTRQDPLSRLSALRDEL 1364

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam1NP_001246162.1 Ig 38..130 CDD:299845
IG 57..133 CDD:214652
IG_like 267..343 CDD:214653 4/8 (50%)
Ig 269..340 CDD:143165 4/5 (80%)
IG_like 353..425 CDD:214653 20/74 (27%)
IGc2 361..413 CDD:197706 16/51 (31%)
I-set 433..527 CDD:254352 30/94 (32%)
IGc2 446..517 CDD:197706 23/70 (33%)
I-set 533..618 CDD:254352 22/90 (24%)
IGc2 544..607 CDD:197706 18/67 (27%)
Ig 641..714 CDD:143165 5/72 (7%)
IGc2 735..804 CDD:197706 16/70 (23%)
I-set 819..914 CDD:254352 23/99 (23%)
Ig 833..921 CDD:299845 20/88 (23%)
FN3 918..1011 CDD:238020 29/104 (28%)
FN3 1018..1116 CDD:238020 23/153 (15%)
FN3 1124..1217 CDD:238020 30/113 (27%)
FN3 1222..1312 CDD:238020 18/90 (20%)
Ig 1339..1406 CDD:299845 16/68 (24%)
FN3 1409..1499 CDD:238020 22/144 (15%)
FN3 1504..1584 CDD:238020 19/82 (23%)
Dscam_C 1890..2008 CDD:289151
igsf9bXP_031761656.1 IG 30..115 CDD:214652 26/79 (33%)
I-set 139..225 CDD:400151 30/94 (32%)
Ig strand A 139..142 CDD:409353 1/2 (50%)
Ig strand A' 148..151 CDD:409353 0/2 (0%)
Ig strand B 157..164 CDD:409353 2/6 (33%)
Ig strand C 170..175 CDD:409353 2/4 (50%)
Ig strand D 185..189 CDD:409353 2/3 (67%)
Ig strand E 191..195 CDD:409353 1/3 (33%)
Ig strand F 204..212 CDD:409353 4/7 (57%)
Ig strand G 215..225 CDD:409353 5/9 (56%)
I-set 229..321 CDD:400151 29/192 (15%)
Ig strand B 246..250 CDD:409353 0/3 (0%)
Ig strand C 260..264 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 3/3 (100%)
Ig strand F 300..305 CDD:409353 3/4 (75%)
Ig strand G 314..317 CDD:409353 3/20 (15%)
Ig 344..405 CDD:409353 15/65 (23%)
Ig strand C 355..360 CDD:409353 1/4 (25%)
Ig strand E 380..384 CDD:409353 2/3 (67%)
Ig strand F 394..399 CDD:409353 2/4 (50%)
Ig 429..505 CDD:416386 20/89 (22%)
Ig strand A' 429..432 CDD:409353 0/2 (0%)
Ig strand B 438..445 CDD:409353 1/6 (17%)
Ig strand C 451..456 CDD:409353 2/12 (17%)
Ig strand C' 458..460 CDD:409353 0/1 (0%)
Ig strand E 471..476 CDD:409353 3/7 (43%)
Ig strand F 484..492 CDD:409353 3/7 (43%)
Ig strand G 495..505 CDD:409353 3/9 (33%)
FN3 510..605 CDD:238020 29/104 (28%)
FN3 622..703 CDD:238020 11/80 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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