Protein Alignment Incenp and Incenp

DIOPT Version :10

• Sequence 1: NP_523648.3
• Gene: Incenp / 35649
• FlyBaseID: FBgn0260991
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_061510338.1
• Gene: Incenp / 1280869
• VectorBaseID: AGAMI1_002910
• Length: 1038
• Species: Anopheles gambiae
• Alignment Length: 1083
• Identity: 272/1083 - (25%)
• Similarity: 408/1083 - (37%)
• Gaps: 375/1083 - (34%)

  Fly     1 MEDILGVLGSLSDLRRELEVLRKAHFEELDHLFYGTGQPEAEAKPRDSAPAAKSQENSSVTPQQT 65
            |:::|.:..|......:.|....|.|.||            |.|..:....||.:.    ||.|.
Mosquito     1 MDELLEMFNSFIGEALDYERAMDAEFVEL------------EKKLSECVSLAKERG----TPVQN 49

  Fly    66 KKRPKRLTSLAEDQNEPEAPDATANNTSARQSTRVSNSQLLAIAEDEHNSTASLM---------- 120
            ||||||..||:|  .|.||...:|.....:...|.|.:..........:|:|.::
Mosquito    50 KKRPKRQASLSE--KEEEASGKSAGEEEEQSEARTSTNDRSTTGGTGKSSSARMLDVSGGKGAGE 112

  Fly   121 ---PPPPVPVSADTTLGSGRPQRAAKLKTEKLLKEPSLNRKMR---------------------- 160
               |.|....::.....|.||.|.|:||.::.||||::..|:|
Mosquito   113 KQAPQPMDTTTSQANESSVRPSRTARLKAQEKLKEPAIGSKLRNDGGTAVTIKLERNSSVANSTL 177

  Fly   161 -RPSSEELVK----------VKVESEQRVSQFNSFTSAQALEENKLAEPELEEPAAETAEQQKPP 214
             |...|.||.          |::|:|...::.|...|..|....|....|....|.| |.|::|.
Mosquito   178 VRGGKEALVAMEKTTLERTYVEMETENDANRANRIISPAAAAAEKRTNDEGFSSANE-ASQKEPA 241

  Fly   215 EEASVTE-DVNTTKTLRVKVKREKLSTEAVPP--------------------------------- 245
            ::|..:| |::......|..|.|.:|.|.:||
Mosquito   242 KQAGKSERDMSLLVVPPVIPKVEIVSDEEMPPPSIMPPPKLPAPKVRTKKKPPVGEKGAKDISDT 306

  Fly   246 -LTNAVSTANVT---TVSSVTTEAARPDDTVASN-----TTTST-EVSKKVRKKKKDVESHRP-- 298
             .::|||:|:.|   |.|||.:..:....|.|.|     |.|.| :..|:|.:........:|
Mosquito   307 ASSSAVSSADSTMNSTASSVRSSVSNSSSTTAKNRVGRPTRTKTKQTGKQVEEPLAAEAPSKPTT 371

  Fly   299 ----------------IKVERFSDLDKSSPVSSRTRKCSSDSRTVQERSIYKDALE--DP----- 340
                            ||.|:.|.:.:....:.||          .::|.|:||.|  :|
Mosquito   372 PPAVLMDVGVLIEPMRIKAEKLSIVQQQPAPADRT----------SDKSNYEDAQEQQEPMEVET 426

  Fly   341 --------------PVAEQSV--------AAVAPAAVNETVAI---------SNATLVLGPAP-- 372
                          .:|.|.:        |.|.|:.:|.|...         |:.|..:.|:.
Mosquito   427 TTNTAQLQSQMRPLKIALQKIPSHELPQQAHVGPSDMNGTYTTGTAAGQPIPSDGTFTMPPSIHD 491

  Fly   373 ---TSDSPI-----GPAGDATFEV--------------HSND-------------------KKQP 396
               |.:||:     .|..:.||.:              |.:|                   :..|
Mosquito   492 GTFTVNSPMENARGAPICNETFNIPAAGGTPPMAGSERHPDDTYVIEKSGGSSGGAGPQQQQHVP 556

  Fly   397 LSKQDSLLTEDESVEEKLP------------TT-------------------------KLLSSIK 424
            |:.. |::|||:||.|..|            ||                         .|..|..
Mosquito   557 LANA-SIMTEDDSVVENSPIQPAPEQLKSKTTTPRTRVAAAAADPPPVPGPKPQRGAAALKKSAS 620

  Fly   425 AIKLPTRTHELFNPLLQSPVKMRVEAFENAANAQNSMRPKRGKDLQGTPGSNNTPKIGKL----P 485
            |:....:..|||||.:.||:|.|:||||..|.|...  |...|  .|||.:    :||:|    .
Mosquito   621 AVADAKKNKELFNPCVMSPIKSRIEAFEKCATATGG--PAASK--IGTPQA----QIGRLMKTVS 677

  Fly   486 APTVG-------------RFFTPTQTTSTL--PLSSAQ-PKKGPASASKATSLLKTAT--GTNLR 532
            .||:|             :.:|.:.::|::  |..:|| |....|||||...:...|.  ||
Mosquito   678 TPTLGTTEPHGITRSAHAKPYTSSSSSSSVYTPNCAAQPPMPKAASASKIGQMQSRALHHGT--- 739

  Fly   533 SVNSTSTKTLSRENSGDDFRKG--------------LHNLAEERKKLREQKHQQAAQQREAKERE 583
            :......::.||::|.|  |.|              ..:|.:|:||.||:|.:.||.||||.|||
Mosquito   740 TSGGGGAQSHSRDSSWD--RAGGGGGSGGTLSAASSTSSLLDEKKKKREEKQRLAAAQREAMERE 802

  Fly   584 RAERMAKLAAERAKK-------QEERKRIE-ERKRQELEELQRKMRQQEEAEALKKAK------- 633
            :.|...:|..|:.:|       ::|:.|:: ::|.::|||.: |.||.||.:.|...|
Mosquito   803 KREHAERLVREKEEKYRKLVQEKQEKLRLDAQKKARKLEEFE-KRRQAEEQKTLADQKRDELAKQ 866

  Fly   634 ----------------------------FKELEQQKL------------QQLTGAKPKKML---- 654
                                        .|:|.||||            ||...|| ||:.
Mosquito   867 LADQERINRELLDTLKQNQTKDAHETKLHKQLYQQKLRQQQQQLEKQHHQQQLAAK-KKLAGGAA 930

  Fly   655 --PPPPKTKYTWEMLHEDDSTDDE------GKVTHKRPPAPTWSRSHVR-GEAIAMQSHCPTDII 710
              ....|..:|:||:..|||||:|      .....:|||.|.|.:.... .:.:.:|:...:.:|
Mosquito   931 GSSAASKKLFTFEMIDTDDSTDEEVSEDTSAPRKKQRPPLPEWCQKTADFRKQLQLQAQLQSSVI 995

  Fly   711 DSFFSVAPTTPDLKQIFPNIDPSQLKRNSSVLWSTPPRYSELP 753
            |..|||.|.||||:.:||:||..:||||||.:|.||||:|:||
Mosquito   996 DRLFSVQPMTPDLRLLFPSIDAQKLKRNSSAIWRTPPRHSQLP 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Incenp	NP_523648.3	PTZ00266	<437..>633	CDD:173502	75/239 (31%)
		MAP7	558..>641	CDD:461709	36/125 (29%)
Incenp	XP_061510338.1	None