DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Br140 and SNT2

DIOPT Version :9

Sequence 1:	NP_001286155.1	Gene:	Br140 / 35648	FlyBaseID:	FBgn0033155	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_011384.1	Gene:	SNT2 / 852746	SGDID:	S000003099	Length:	1403	Species:	Saccharomyces cerevisiae

Alignment Length:	222	Identity:	57/222 - (25%)
Similarity:	92/222 - (41%)	Gaps:	48/222 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   286 CCICLDGECQNTNVILFCDMCNLAVHQDCYGVPYIPEG----------QWLCRRCLQ--SP--SK 336
            |.:|.:....|.|..:.|..|.|.||..||.:. :|:.          :|||..|..  :|  |.
Yeast  1041 CSVCKEKFNDNDNYEVVCGNCGLTVHYFCYAIK-LPKDMKKNTNLKTFKWLCDPCSNDLNPIIST 1104

  Fly   337 PVNCVLCPN---------------AGGAFKQTDHGQWAHVVCALWIPEVRFANTVFLEPIDSIET 386
            ...|.:||.               ...|.|.|..|.|.|:||:|:..::::.|...::|..:...
Yeast  1105 TYQCSMCPTKDYDYDRYRSQSFKICPDALKCTSLGTWVHLVCSLFNEDIKYGNGQSMQPALNTTA 1169

  Fly   387 IPPARWRLTCYVCKEKGLGACIQCHRNSCYAAFHVTCAQQAGLY--------MTMDT----VKDG 439
            :.....|.||.||:..| |..::|  |.|...:|:||||.:..:        |::||    :||.
Yeast  1170 VLIKHSRFTCGVCRING-GGLVKC--NKCQYRYHITCAQNSSNFKLMFEKKNMSVDTTLPCIKDV 1231

  Fly   440 HNDSSMHVQKFAYCHAHTPADAKLKMN 466
            ..:.:..::....|..|   |..|:.|
Yeast  1232 KLNDTYTLRPILICDRH---DISLEGN 1255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_001286155.1	EPL1	<192..264	CDD:287484
		PHD_BRPF	283..336	CDD:277047	17/63 (27%)
		ePHD_BRPF	340..456	CDD:277140	35/142 (25%)
		Bromo_brd1_like	615..712	CDD:99944
		BR140_related	1303..1414	CDD:99900
SNT2	NP_011384.1	BAH_fungalPHD	112..256	CDD:240061
		PHD1_Snt2p_like	319..366	CDD:276972
		Myb_DNA-binding	559..602	CDD:395191
		PHD2_Snt2p_like	1040..1094	CDD:276973	15/53 (28%)
		ePHD_Snt2p_like	1108..1248	CDD:277137	35/142 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810