DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Br140 and SDG29

DIOPT Version :9

Sequence 1:	NP_001286155.1	Gene:	Br140 / 35648	FlyBaseID:	FBgn0033155	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_200155.2	Gene:	SDG29 / 835424	AraportID:	AT5G53430	Length:	1043	Species:	Arabidopsis thaliana

Alignment Length:	488	Identity:	125/488 - (25%)
Similarity:	190/488 - (38%)	Gaps:	128/488 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 PLEENAPWARVQVPVARVAEIPDYRVSDAPP-RPLAYYRFIEKSLEELDGEVEYDVDEEDSAWLE 235
            ||||   |      :.::||......:..|| ||
plant   557 PLEE---W------MMKLAEFHANATAAKPPKRP------------------------------- 581

  Fly   236 HMNEERQRLGLNAVGIDTMELLMDRLEKESHFQAAANGTPTGVEVDDDAVCCICLDGECQNTNVI 300
            .:.:.:|||         :..|.::.|            |..|:...:. |.:|...|..:.|.|
plant   582 SIKQRKQRL---------LSFLREKYE------------PVNVKWTTER-CAVCRWVEDWDYNKI 624

  Fly   301 LFCDMCNLAVHQDCYGVPYIPE-GQWLCRRCLQSPSKPVNCVLCPNAGGAFKQTD-HGQWAHVVC 363
            :.|:.|.:||||:|||...:.: ..|:|:.| ::|.....|.|||..|||.|.|| ...|.||.|
plant   625 IICNRCQIAVHQECYGTRNVRDFTSWVCKAC-ETPEIKRECCLCPVKGGALKPTDVETLWVHVTC 688

  Fly   364 ALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKGLGACIQCHRNSCYAAFHVTCAQQAG 428
            |.:.|||.||:...:||...|.:||.:.:...|.:||:.. |:|.||.:.|.|  :|..||.:||
plant   689 AWFQPEVCFASEEKMEPALGILSIPSSNFVKICVICKQIH-GSCTQCCKCSTY--YHAMCASRAG 750

  Fly   429 LYMTMDTV-KDGHNDSSMHVQKFAYCHAHTP--ADAKLKMNVPD--FED---TRHKMKE-ARKAL 484
            ..|.:..: |:|...:.|    .:||..|..  .|..|.:..|.  |..   .::|.|. .|..|
plant   751 YRMELHCLEKNGRQITKM----VSYCSYHRAPNPDTVLIIQTPSGVFSAKSLVQNKKKSGTRLIL 811

  Fly   485 AKKRSTAPVVLIPTIPPDRVQEIATMV---TMQRKKEFLDRIIAYWT--LKRH------------ 532
            |.:..........|||.|........:   |:..||...:..|.::|  |:.|
plant   812 ANREEIEESAAEDTIPIDPFSSARCRLYKRTVNSKKRTKEEGIPHYTGGLRHHPSAAIQTLNAFR 876

  Fly   533 -----------YRNGVPLLRRLQSQGNNHGVIQRNGIEG-------SPDTGELYRQLKYWQC--L 577
                       :|..:..|:|.:.:....|   |:||.|       :...||:..:.:..|.  :
plant   877 HVAEEPKSFSSFRERLHHLQRTEMERVCFG---RSGIHGWGLFARRNIQEGEMVLEYRGEQVRGI 938

  Fly   578 RQDLERARLLCELVRKREKLKVAFVRISEEVVM 610
            ..||..||.      :||.......:||||||:
plant   939 IADLREARY------RREGKDCYLFKISEEVVV 965

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_001286155.1	EPL1	<192..264	CDD:287484	9/72 (13%)
		PHD_BRPF	283..336	CDD:277047	18/53 (34%)
		ePHD_BRPF	340..456	CDD:277140	45/117 (38%)
		Bromo_brd1_like	615..712	CDD:99944
		BR140_related	1303..1414	CDD:99900
SDG29	NP_200155.2	PWWP	221..324	CDD:295359
		PHD_TCF19_like	415..466	CDD:276992
		PHD_ATX3_4_5_like	609..655	CDD:276970	16/46 (35%)
		ePHD_ATX3_4_5_like	664..775	CDD:277133	45/117 (38%)
		SET	901..1024	CDD:214614	20/74 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13793
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X459
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010