DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Br140 and ATX1

DIOPT Version :9

Sequence 1:	NP_001286155.1	Gene:	Br140 / 35648	FlyBaseID:	FBgn0033155	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_850170.1	Gene:	ATX1 / 817721	AraportID:	AT2G31650	Length:	1062	Species:	Arabidopsis thaliana

Alignment Length:	490	Identity:	127/490 - (25%)
Similarity:	191/490 - (38%)	Gaps:	116/490 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 VLTPSRKKARSR--SGGHHSTPRPHKDHPTPG-----GGGAEARNGCSSASAGGGSASGVSARQY 115
            :|:||..|.:..  ..|........|.|..|.     ..||::.:...:.|...|::.|
plant   366 LLSPSHLKCKQPRFEEGMQEAKMYLKAHRLPERMSQLQKGADSVDSDMANSTEEGNSGG------ 424

  Fly   116 ANPESLVSYNEEEATVTFNLDGKSVRLGIDDAL-----PLVEDEEFAALVARGCILNADAPPLEE 175
                .|::..|.....|.::|.:.:   |.|.|     .:|.|.:|..               :|
plant   425 ----DLLNDGEVWLRPTEHVDFRHI---IGDLLIINLGKVVTDSQFFK---------------DE 467

  Fly   176 NAPWARVQVPVARVAEIPDYRVS---------DAP-------------------PRPLAYYRFIE 212
            |..|......:.:...:.|:..|         ||.                   |.|.|.:..|.
plant   468 NHIWPEGYTAMRKFTSLTDHSASALYKMEVLRDAETKTHPLFIVTADSGEQFKGPTPSACWNKIY 532

  Fly   213 KSLEELDGEVEYDVDEEDSAWLEHMNEERQRLGLNAVGIDTMELL-----MDRLEKESHFQAAAN 272
            ..:::        |...||..:  :.||....|.:..|:...|::     :.:....||.....|
plant   533 NRIKK--------VQNSDSPNI--LGEELNGSGTDMFGLSNPEVIKLVQDLSKSRPSSHVSMCKN 587

  Fly   273 ------GTPTG---VEVD--DDAVCCIC-LDGECQNTNVILFCDMCNLAVHQDCYGVPYIPEGQ- 324
                  ..|||   |.||  |...|.:| :|.|.:| |:.|.||.|.:.||..|||.....:|.
plant   588 SLGRHQNQPTGYRPVRVDWKDLDKCNVCHMDEEYEN-NLFLQCDKCRMMVHAKCYGELEPCDGAL 651

  Fly   325 WLCRRCLQ-SPSKPVNCVLCPNAGGAFKQTDHGQWAHVVCALWIPEVRFANTVFLEPIDSIETIP 388
            |||..|.. :|..|..|.|||..|||.|.|..|:|||:.||:||||...::...:||||.:..:.
plant   652 WLCNLCRPGAPDMPPRCCLCPVVGGAMKPTTDGRWAHLACAIWIPETCLSDVKKMEPIDGVNKVS 716

  Fly   389 PARWRLTCYVCKEKGL--GACIQCHRNSCYAAFHVTCAQQAGLYMTMDTVKDGHNDSSMH----- 446
            ..||:|.|.:|   |:  ||||||..|||..|:|..||:.|||.:.::      ||.|:.
plant   717 KDRWKLMCTIC---GVSYGACIQCSNNSCRVAYHPLCARAAGLCVELE------NDMSVEGEEAD 772

  Fly   447 --VQKFAYCHAHTPADAKLKMNVPDFEDTRHKMKE 479
              ::..::|..|.........:....:...||..|
plant   773 QCIRMLSFCKRHRQTSTACLGSEDRIKSATHKTSE 807

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_001286155.1	EPL1	<192..264	CDD:287484	16/104 (15%)
		PHD_BRPF	283..336	CDD:277047	21/55 (38%)
		ePHD_BRPF	340..456	CDD:277140	49/124 (40%)
		Bromo_brd1_like	615..712	CDD:99944
		BR140_related	1303..1414	CDD:99900
ATX1	NP_850170.1	TUDOR	<215..248	CDD:295375
		PWWP	299..389	CDD:279227	5/22 (23%)
		FYRN	448..497	CDD:283589	10/63 (16%)
		FYRC	508..597	CDD:295414	15/98 (15%)
		PHD_ATX1_2_like	611..657	CDD:276969	19/46 (41%)
		ePHD_ATX1_2_like	668..784	CDD:277132	49/124 (40%)
		SET	898..1017	CDD:214614
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13793
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X459
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010