Protein Alignment Br140 and kdm4c

DIOPT Version :9

• Sequence 1: NP_001286155.1
• Gene: Br140 / 35648
• FlyBaseID: FBgn0033155
• Length: 1430
• Species: Drosophila melanogaster
• Sequence 2: NP_001077320.1
• Gene: kdm4c / 570194
• ZFINID: ZDB-GENE-070209-38
• Length: 1482
• Species: Danio rerio
• Alignment Length: 511
• Identity: 122/511 - (23%)
• Similarity: 191/511 - (37%)
• Gaps: 146/511 - (28%)

  Fly    15 KTQQSQPPFACPVR---GCDRSYKTIMGLQ--YHLMKYDHDNPQPLTPVLTPSRKKARSRSGGHH 74
            :.::.:|..||.:.   |.....:....:|  |..:|.:||
Zfish   908 ENEEVEPAEACELNEQAGSQEPQEREFKIQEYYRSVKSEHD------------------------ 948

  Fly    75 STPRPHKDHPTPGGGGAEARNGCSSASAGGGSASGVSARQ-YANPESLVSYNEEEATVTFNLD-- 136
                          |.....:.|.|...|..|:|..|... .::||.:.:..|.....|:::.
Zfish   949 --------------GSVSDSDSCESGDKGADSSSESSEENPMSDPEYVETGLEPGEVCTYHMQTV 999

  Fly   137 ---GKS----VRLGIDDALPLVEDEEFAA--LVARGCILNADAPPLEENAPWARVQVPVARVAEI 192
               .||    :|.....|:|....::.|:  .|...|....|.|..||   ||:   |:..:.:
Zfish  1000 KKTAKSWRHPLRKPTARAVPSAVKQQAASDDEVIEECASEEDEPETEE---WAK---PLVHLWQ- 1057

  Fly   193 PDYRVSDAPPRPLAYYRFIEKSLEELDGEVEYDVDEEDSA-------------WLEHMNEERQRL 244
                      ...|::::          |.||::....:|             ..|::.|.|..:
Zfish  1058 ----------HRKAHFQY----------EQEYNMTAAKNAPHCAVCTLFMPYHQPENLEERRPEV 1102

  Fly   245 GLNAVGIDTMELLMDRLEKESHFQAAANGTPTGVEVDDDAVCCICLDGEC--------QNTNVIL 301
            .:.:..:|                |.:...|...|     :|....:|.|        ..::.::
Zfish  1103 SMGSCSLD----------------AGSRSRPLIPE-----ICFAYQEGPCPLNTLLEEDGSSPLV 1146

  Fly   302 FCDMCNLAVHQDCYGVPYIPEGQ-WLCRRCLQSPSKPVNCVLCPNAGGAFKQTDHGQWAHVVCAL 365
            .|..|.:.||..||||.....|. |.|.||: |......|.||...|||.|:|...:|.||:||:
Zfish  1147 VCSSCCVQVHASCYGVSAQDVGPVWTCDRCV-SEDLAAGCCLCNLRGGALKRTSDDRWVHVMCAV 1210

  Fly   366 WIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKE--KGL-GACIQCHRNSCYAAFHVTCAQQA 427
            .:|||:|.:.|...||| |..:|..|::|.|..|:.  |.| ||||||....|..:||||||..|
Zfish  1211 GLPEVKFIDVVKRAPID-ISAVPVQRYKLKCIYCRNRIKRLSGACIQCSCGRCPTSFHVTCAHAA 1274

  Fly   428 GLYMTMDTVKDGHNDSSMHVQKFAYCHAH--TPADAKLKMNVPDFE-----DTRHK 476
            |:.|..|       |....|  |..||.|  ..:.||:|::..:.|     .::||
Zfish  1275 GVPMEPD-------DWPYVV--FITCHRHQSRSSSAKVKVSKSELEVGQTVISKHK 1321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_001286155.1	EPL1	<192..264	CDD:287484	9/84 (11%)
		PHD_BRPF	283..336	CDD:277047	17/61 (28%)
		ePHD_BRPF	340..456	CDD:277140	51/118 (43%)
		Bromo_brd1_like	615..712	CDD:99944
		BR140_related	1303..1414	CDD:99900
kdm4c	NP_001077320.1	JmjN	16..57	CDD:128818
		JmjC	177..293	CDD:202224
		PHD_SF	1079..1176	CDD:304600	21/117 (18%)
		ePHD_JMJD2C	1185..1294	CDD:277185	51/118 (43%)
		TUDOR	1308..1364	CDD:197660	3/14 (21%)
		TUDOR	1366..1421	CDD:197660

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810